Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$195K - $217K *

Drive client success by leading strategic initiatives and fostering strong relationships in healthcare technology. Leverage deep domain expertise to enhance outcomes and ensure effective use of soluti...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform data into actionable insights by building robust data pipelines, dashboards, and monitoring frameworks. Leverage expertise in Skyline DataMiner to enhance network performance analytics and e...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Staffing

$174K - $374K *

Champion equitable healthcare by providing exceptional primary care to Medicare patients. Collaborate with a dedicated team to enhance patient outcomes and experience in a supportive, innovative envir...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Elevate healthcare delivery by providing remote GI services to Veterans. Collaborate with facility leaders to establish clinics, manage patient panels, and ensure timely access to care while adhering...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Empower your career as a staff pharmacist, overseeing medication management, patient care, and support personnel. Collaborate with healthcare teams to ensure safe, effective therapies across diverse p...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $135K *

Elevate your career by independently leading high-impact sales enablement initiatives. Utilize your expertise in strategic selling and data-driven insights to improve sales performance and nurture cro...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Lead the full lifecycle of contracts, ensuring compliance and risk mitigation. Collaborate with internal teams and external partners to draft, negotiate, and manage contracts effectively, while mainta...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$210K - $250K *

Empower oncology research by leveraging real-world evidence and clinical expertise. Collaborate with cross-functional teams to develop innovative solutions that enhance cancer treatment and support bi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in managing the Financial Investigations & Provider Review department, focusing on pharmaceutical fraud detection and recovery. Guide a team of investigators to enhance compliance and...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$117K - $156K *

Lead nursing personnel to ensure exceptional patient care and operational efficiency. Develop staffing solutions and maintain clinical standards while promoting interdisciplinary collaboration within...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Unlock potential by managing system design, build, and support for applications, ensuring optimal functionality and user satisfaction while collaborating across teams to enhance workflows and resolve...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$132K - $153K *

Join a team that's redefining care management by leading strategic initiatives in utilization and appeals processes. Drive high-quality, cost-effective care while ensuring compliance and fostering a c...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$74K - $87K *

Transform customer experiences by leading Unanet ERP implementations, ensuring successful configurations and training for Government Contracting clients. Manage multiple projects, driving adoption and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$75K - $95K *

Shape the future of clinical research data integrity by leading a dedicated team. Drive operational excellence, ensure compliance, and foster cross-functional partnerships to enhance data quality and...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$176K - $227K *

Advance cybersecurity initiatives by providing strategic legal counsel on data security, incident response, and regulatory matters. Collaborate with cross-functional teams to mitigate risks and suppor...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Champion the future of design education by leading a pioneering PhD program in Transition Design, fostering innovative research, and guiding doctoral candidates to explore complex societal and ecologi...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$160K - $192K *

Accelerate progress at the forefront of healthcare by driving commercial performance, building relationships with providers, and ensuring patient access to innovative therapies across a defined territ...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $250K *

Champion growth in GI health by building strategic relationships and driving sales through effective engagement with healthcare providers. Collaborate with cross-functional teams to enhance product ac...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $149K *

Advance the organization by establishing robust data and AI governance practices. Collaborate across teams to ensure compliance, integrity, and responsible usage of data and AI assets, supporting both...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Healthcare

$107K - $142K *

Support high-risk pregnancy care by providing prenatal and postnatal services, coordinating multidisciplinary team efforts, and assisting in fetal procedures. Join a pioneering team dedicated to advan...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $210K *

Shape the future of precision medicine by managing executive relationships and driving enterprise-wide adoption of molecular diagnostics. Collaborate across teams to implement strategic initiatives an...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Shape strategic partnerships in precision medicine by managing executive relationships and driving enterprise-wide adoption of molecular diagnostics. Collaborate across teams to ensure successful impl...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$85K - $100K *

Lead the charge in providing comprehensive women's health services as a vital member of a multidisciplinary team. Deliver exceptional care, including prenatal, postpartum, and well-woman services, whi...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Optimize patient outcomes by delivering clinical pharmacy services, ensuring compliance with regulations, and collaborating with healthcare teams to implement safe, cost-effective drug therapies that...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$78K - $113K *

Join us to lead the Professional Coding Operations team, ensuring accurate coding practices and compliance. Collaborate with stakeholders, mentor staff, and drive improvements in coding efficiency and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.