Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$107K - $142K *

Shape the future of clinical operations by providing leadership and oversight to ensure efficient hospital flow, patient safety, and staff performance while fostering a culture of excellence and conti...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $160K *

Elevate our deal desk function by transforming processes into a scalable model. You'll implement AI tools, streamline order forms, and ensure efficient deal structuring while collaborating with cross...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$195K - $225K *

Drive security innovation by shaping technical strategies and frameworks that protect sensitive data and systems. Collaborate across teams to embed security practices, mentor engineers, and ensure com...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$102K - $177K *

Lead the charge in enhancing patient access to therapies by educating healthcare providers, resolving issues, and collaborating with stakeholders to ensure seamless treatment journeys for patients in...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Empower our finance team by overseeing accounting operations, ensuring compliance, and enhancing financial reporting. Lead month-end close activities and mentor team members in a dynamic, multi-entity...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Contribute to the development of innovative healthcare software by analyzing product requirements, documenting features, and ensuring compliance in Anatomic Pathology. Collaborate with cross-functiona...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$186K - $202K *

Pioneer innovative engineering solutions by leading technical strategy and architecture for a growing platform. Collaborate across teams to drive scalable, reliable systems while ensuring alignment wi...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$88K - $105K *

Support the Nursing Unit Director in managing clinical and administrative activities, ensuring high-quality patient care and operational efficiency within the designated unit and department...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$94K - $107K *

Support and enhance data governance operations by collaborating with teams to implement standards, manage data cataloging, and drive tool adoption, ensuring compliance and effective governance workflo...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Lead national physician engagement and business development for a fertility pharmacy, managing a multi-layered team to drive growth and build executive relationships across clinics and provider networ...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Optimize patient medication services by ensuring accurate prescription fulfillment, supervising pharmacy operations, and providing expert consultations to enhance pharmaceutical care...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $180K *

Drive the modernization of Veterans Benefits Administration claims processing by designing and optimizing scalable data pipelines and solutions, ensuring efficient data integration and analytics for i...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$145K - $156K *

Join a team that's dedicated to enhancing the lives of young children through personalized occupational therapy. Enjoy flexible scheduling and competitive pay while making a meaningful impact in your...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $156K *

Take ownership of transformative early intervention services for children 0-3. Collaborate with families to create personalized treatment plans, ensuring compliance and advocacy while enjoying flexibl...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in building and managing a lien negotiation function, overseeing complex medical lien resolutions while driving team performance and compliance to maximize client recoveries and stream...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$80K - $100K *

Drive innovative palliative care solutions for members with complex needs, providing compassionate, evidence-based support through telehealth. Collaborate with interdisciplinary teams to enhance patie...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$250K - $250K+*

Partner with us to support research initiatives by assisting in human subject activities, data collection, and regulatory submissions, while collaborating with a dedicated team to advance clinical res...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $125K *

Drive operational excellence in patient access by leading teams, enhancing processes, and fostering collaboration across healthcare facilities. Your leadership will ensure compliance, improve patient...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Empower children with autism by delivering evidence-based ABA services. Manage a focused caseload while collaborating with a dedicated team to ensure ethical practices and client progress in a support...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Unlock the potential of patient care by optimizing medication therapy, ensuring compliance, and collaborating with healthcare teams to enhance safety and efficacy in pharmaceutical practices while ser...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$155K - $175K *

Lead the charge in client partnerships while driving strategic growth and team development. Utilize your expertise to deliver impactful insights and solutions in a fast-paced, evolving environment, en...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Transform healthcare engagement by driving commercial performance and building strong relationships with providers. Collaborate cross-functionally to support product launches and ensure patient access...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive patient care excellence as a Senior Physical Therapist, utilizing advanced clinical skills to assess and treat diverse patient populations while mentoring staff and contributing to program devel...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$125K - $150K *

Shape the future of security by engineering robust controls for endpoints and email. As a Staff Security Engineer, you'll enhance our security posture, mentor peers, and ensure compliance in a regulat...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$115K - $130K *

Unlock potential by driving data analysis and interpreting clinical trial results. Collaborate with stakeholders, ensure statistical integrity, and contribute to innovative methodologies in biostatist...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.