Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

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$150K - $180K *

Engage with key healthcare clients to drive strategic account management, fostering relationships and delivering tailored solutions across GE HealthCare’s diverse portfolio, while leading cross-functi...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Business Services

$90K - $110K *

Join a team that's dedicated to delivering exceptional emergency care across diverse patient populations, collaborating closely with physicians and nursing staff to ensure high-quality treatment in a...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Engage in dynamic emergency care, providing essential support to patients across all ages. Collaborate with a dedicated team to deliver high-quality medical services in a fast-paced environment, ensur...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K - $230K *

Accelerate progress at the forefront of clinical supply chain management, leading strategic initiatives to ensure seamless delivery of investigational products for global trials while collaborating ac...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join our dynamic team of healthcare professionals, tackling diverse clinical challenges in a state-of-the-art urgent care setting. Enjoy flexible scheduling and collaborate with a dedicated team to pr...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Transform patient care by delivering high-quality urgent care services. Collaborate with a dedicated team in a state-of-the-art facility, addressing diverse clinical challenges while ensuring patient...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Elevate your clinical career by joining a dynamic team of healthcare professionals. Engage in diverse patient care, utilize advanced technology, and collaborate with a supportive staff in a well-maint...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Elevate your career by joining our dynamic team of healthcare professionals. Engage in diverse clinical challenges, collaborate with skilled colleagues, and enjoy flexible scheduling in a state-of-the...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$125K - $150K *

Join a team that's redefining veterinary care by leveraging advanced imaging technology and collaboration. As a key Radiologist, you'll enhance diagnostics across specialties, ensuring optimal patient...

Reposted yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Partner with us to drive transformative healthcare solutions by managing key accounts, fostering relationships, and ensuring measurable outcomes. Your expertise will enhance provider partnerships and...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$170K - $200K *

Join a team that's dedicated to delivering exceptional anesthesia care. Collaborate with healthcare professionals to ensure patient safety and comfort during procedures, while utilizing your expertise...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$90K - $110K *

Innovate data solutions by developing complex reports and analyses to support senior management and client needs. Collaborate with teams to enhance data literacy and provide technical guidance across...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$123K - $157K *

Lead the charge in global sourcing strategies for plastics, driving supplier relationships and cost optimization while ensuring supply continuity and supporting new product introductions across manufa...

RemoteRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Join a dedicated team providing comprehensive anesthetic care, ensuring the highest safety standards for patients. Contribute to quality improvement initiatives while mentoring new nurse anesthetists...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$170K - $200K *

Bring your expertise to our dynamic anesthesiology team, providing top-notch anesthetic care while collaborating with healthcare professionals to ensure optimal patient safety and comfort throughout t...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$180K - $220K *

Unlock your potential by driving enterprise growth in healthcare. Join a dynamic team focused on building relationships with health systems and provider organizations, leveraging a robust support engi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$86K - $138K *

Lead the charge in defining and executing a comprehensive product strategy, driving value across product portfolios. Collaborate with key stakeholders to align strategic vision while overseeing perfor...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a dynamic team as an Audit Partner, delivering tailored audit and assurance services to middle market clients. Leverage your expertise to mentor staff, drive business growth, and build lasting cl...

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Unlock potential by leading audit services for middle market clients. Collaborate with firm leadership, mentor staff, and drive business growth while becoming an industry expert. Enjoy flexibility and...

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Champion the growth of middle market clients by delivering expert audit and assurance services. Collaborate with leadership, mentor staff, and drive business development while fostering meaningful cli...

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$135K - $160K *

Lead the strategic design and management of comprehensive benefits programs, ensuring alignment with employee needs and company objectives. Drive innovation and compliance while enhancing employee eng...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$520K+ *

Shape the future of patient care by leading the anesthesia team, ensuring excellence in perioperative management and patient safety, while collaborating in a supportive community-oriented environment...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Drive impactful senior care by delivering high-quality, relationship-based primary care. Collaborate with interdisciplinary teams to enhance patient outcomes and maintain independence for residents in...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Empower patient care by delivering comprehensive healthcare services, including evaluations, treatments, and education, while collaborating with healthcare teams to enhance patient outcomes and satisf...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$105K - $150K *

Lead the charge in executive support and strategic sales initiatives, managing schedules, communications, and events for the EVP of Global Client Services. Drive efficiency and stakeholder engagement...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.