Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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Dentist Jobs in Pennsylvania

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$160K - $192K *

Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Join a team that's dedicated to advancing veterinary dermatology through collaboration and advanced diagnostics. You'll manage complex skin conditions in a supportive multispecialty environment, enhan...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$250K - $275K *

Join us to lead clinical operations for a multi-state virtual care team, ensuring high-quality, timely care. This role combines direct patient care, administrative leadership, and strategic oversight...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$174K - $374K *

Strategize clinical oversight and drive innovative medical management programs. Collaborate with a multidisciplinary team to enhance member care outcomes while representing the organization to externa...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $300K *

Elevate patient care by utilizing advanced wound healing techniques in a collaborative environment. Engage with diverse patient populations, providing comprehensive treatment and follow-up in skilled...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $210K *

Empower pediatric care by joining a supportive team in a well-equipped outpatient setting. Enjoy competitive compensation, comprehensive benefits, and opportunities for professional growth while makin...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Champion patient-centered care by joining a dynamic Internal Medicine practice. Engage with a supportive team, providing quality healthcare while enjoying a balanced work-life schedule in a mission-dr...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $90K *

Empower patients to achieve optimal physical health by evaluating needs, creating tailored care plans, and delivering effective treatments. Collaborate with a dedicated team to enhance patient outcome...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Elevate your career by leading a dedicated team of clinicians while providing exceptional patient care. Drive clinic performance and foster a culture of learning and accountability in a supportive env...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Champion compassionate care by providing comprehensive internal medicine services, focusing on acute and chronic disease management, preventive care, and public health initiatives. Join a collaborativ...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Shape the future of orthopedic care by providing advanced clinical support to a spine surgeon. Collaborate with a dedicated team to assess, diagnose, and treat patients while ensuring high-quality car...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $205K *

Join a team that's driving the future of secure enterprise architecture. You'll shape scalable strategies across various domains, collaborate with stakeholders, and ensure innovation aligns with cyber...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

$180K - $200K *

Transform the transplant landscape by driving sales and adoption of innovative genetic testing solutions. Engage with key stakeholders to enhance patient care and achieve strategic business goals in a...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Elevate your career by leading financial planning and analysis, managing budgets, and driving strategic insights. Collaborate with cross-functional teams to enhance operational performance and deliver...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $300K *

Drive excellence in pediatric plastic surgery by leading a top-tier program, overseeing patient care, education, and research initiatives while mentoring future leaders in the field...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$138K - $172K *

Empower revenue teams as a Senior Business Systems Analyst, driving efficiency through Salesforce architecture, process design, and actionable data across GTM, Marketing, Sales, and Customer Success o...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Join our collaborative healthcare team as a Certified Nurse Midwife, providing comprehensive care to patients. Engage in assessments, consultations, and patient education while working closely with ph...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Transform technology operations by leading IT and cybersecurity strategies, ensuring secure, scalable systems while enhancing employee support in a dynamic, remote-first environment. Collaborate acros...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$300K - $350K *

Join a dynamic team providing advanced surgical care for colorectal conditions. Collaborate within a leading healthcare system, utilizing cutting-edge techniques and technologies. Ideal for experience...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $95K *

Empower patients on their recovery journey by providing tailored Physical Therapy solutions. Collaborate with a multidisciplinary team to enhance mobility, alleviate pain, and foster a supportive envi...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$75K - $95K *

Champion patient recovery by providing tailored Physical Therapy solutions in a dynamic, customer-focused environment. Collaborate with a dedicated team to enhance mobility and well-being, ensuring a...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Join a team that's dedicated to delivering exceptional pharmaceutical care by reviewing medication records, dispensing medications, and supervising pharmacy staff while ensuring compliance with regula...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $120K *

Join a team that's dedicated to enhancing billing operations while supervising a skilled group of Billing Coordinators. This role combines leadership with hands-on billing responsibilities to ensure e...

6 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$72K - $99K *

Join a team that's dedicated to enhancing employee experience and office operations. You'll manage daily office functions, foster a vibrant culture, and support executive initiatives, ensuring a welco...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$180K - $220K *

Grow your career with a unique blend of clinical practice and leadership. Lead a team of 75-100 physicians while driving quality initiatives and strategic growth across a network of urgent care center...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.