Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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Dentist Jobs in Pennsylvania

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$71K - $95K *

Empower the future of EDI and integration systems by designing, developing, and managing solutions that enhance business processes, ensuring reliability and efficiency while collaborating with cross-f...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Champion comprehensive healthcare by providing primary and women's health services in a collaborative environment. Engage with diverse patient populations while ensuring quality care and support for u...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$360K - $400K *

Unlock potential by joining our dynamic clinical team as an Adult Psychiatrist. Enjoy flexible schedules, competitive compensation, and a supportive environment focused on outpatient care and work-lif...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $250K *

Join a team that's optimizing medical cost management and driving financial performance across Commercial lines. Leverage your expertise in healthcare economics to influence strategic contracting and...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Unlock potential by joining a dynamic veterinary team focused on quality care, mentorship, and collaboration. Enjoy a flexible schedule with no overnight shifts while tackling diverse cases in a suppo...

3 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$79K - $127K *

Unlock insights into medical cost trends by leveraging data analytics. Collaborate with cross-functional teams to develop strategic recommendations, track program outcomes, and present findings clearl...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $100K *

Transform patient care by managing inpatient services, collaborating with physicians, and providing education. Leverage your expertise to assess and treat complex conditions while ensuring compliance...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$227K - $385K *

Elevate member care by overseeing utilization management and evaluating treatment appropriateness. Collaborate with multidisciplinary teams, ensuring compliance with clinical standards and regulations...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Optimize patient care by joining a dynamic OB/GYN team, focusing on outpatient services with a supportive environment. Collaborate with experienced professionals to enhance health outcomes and ensure...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$360K - $400K *

Pioneer in mental health care by providing exceptional outpatient psychiatric services. Collaborate with a dedicated team to enhance patient well-being through innovative treatment options and flexibl...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Transform healthcare delivery by providing critical care services in diverse settings, focusing on chronic conditions. Collaborate with physicians, educate patients, and ensure compliance with standar...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $150K *

Champion effective publication strategies and lead scientific communication initiatives, acting as a strategic partner to clients and teams. Navigate complex medical affairs content to drive impactful...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Advance urgent care standards by delivering high-quality, on-demand services in collaboration with a skilled team. Enjoy a wide scope of practice in a supportive environment that promotes professional...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Help us provide comprehensive psychiatric care by developing treatment plans, coordinating with healthcare teams, and ensuring patients receive the support they need within our facilities. Your expert...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $300K *

Contribute to advanced Gynecologic Oncology care while fostering education and research in a collaborative environment. Join a dynamic team dedicated to improving patient outcomes and supporting work...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$86K *

Lead patient care initiatives by assessing, planning, and delivering high-quality nursing services. Collaborate with interdisciplinary teams to enhance patient outcomes and ensure safety while fosteri...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Unlock potential by delivering comprehensive orthopedic care, collaborating with healthcare teams, and ensuring quality patient outcomes through diagnostic and therapeutic services across various sett...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$160K - $192K *

Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Join a team that's dedicated to advancing veterinary dermatology through collaboration and advanced diagnostics. You'll manage complex skin conditions in a supportive multispecialty environment, enhan...

Reposted yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$250K - $275K *

Join us to lead clinical operations for a multi-state virtual care team, ensuring high-quality, timely care. This role combines direct patient care, administrative leadership, and strategic oversight...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$174K - $374K *

Strategize clinical oversight and drive innovative medical management programs. Collaborate with a multidisciplinary team to enhance member care outcomes while representing the organization to externa...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $300K *

Elevate patient care by utilizing advanced wound healing techniques in a collaborative environment. Engage with diverse patient populations, providing comprehensive treatment and follow-up in skilled...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $210K *

Empower pediatric care by joining a supportive team in a well-equipped outpatient setting. Enjoy competitive compensation, comprehensive benefits, and opportunities for professional growth while makin...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Champion patient-centered care by joining a dynamic Internal Medicine practice. Engage with a supportive team, providing quality healthcare while enjoying a balanced work-life schedule in a mission-dr...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $90K *

Empower patients to achieve optimal physical health by evaluating needs, creating tailored care plans, and delivering effective treatments. Collaborate with a dedicated team to enhance patient outcome...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.