Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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Dentist Jobs in Pennsylvania

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$80K - $100K *

Empower your career by delivering patient-centered care through skilled interventions and evidence-based plans. Collaborate with patients to enhance their recovery journey and achieve meaningful outco...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Empower patients by assessing movement dysfunction and crafting personalized care plans. Deliver skilled interventions to enhance recovery, track outcomes, and advocate for patient needs throughout th...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Join a dynamic team dedicated to optimizing patient care through safe, effective pharmaceutical practices. Oversee operations, provide drug information, and ensure compliance while mentoring support s...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive excellence in clinical medical physics by ensuring quality assurance, compliance, and patient care in Radiation Oncology. Collaborate with healthcare teams to enhance treatment outcomes and supp...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Engage in delivering exceptional emergency care by joining a dedicated team. Utilize your expertise in a dynamic environment, ensuring patient safety and well-being while collaborating with healthcare...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by leading anesthesia services in a collaborative veterinary team, enhancing patient care and outcomes while contributing to a thriving specialty hospital network dedicated to excelle...

Reposted yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Lead patient care collaboration, demonstrating autonomy in assessment, diagnosis, and treatment, while ensuring effective communication and advocating for patient needs within the healthcare team fram...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Lead and coordinate large-scale risk management projects, ensuring compliance with regulatory standards while collaborating with diverse teams to enhance organizational effectiveness and mitigate risk...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $100K *

Champion high-quality veterinary care by joining a collaborative team that fosters growth in a state-of-the-art facility. Engage in diverse practices including urgent care and surgery, while enjoying...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Explore a rewarding role providing comprehensive patient care, diagnosing and treating illnesses, and guiding preventive health strategies. Collaborate in a dynamic clinical environment while making a...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $140K *

Elevate patient care by providing expert dermatological services in a compassionate and flexible environment. Full-time or part-time opportunities available with no weekend shifts, ensuring a healthy...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K *

Empower patients by delivering high-quality telehealth services across Pennsylvania. Join a dynamic team of board-certified physicians providing compassionate care for a wide range of clinical cases t...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K *

Champion innovative telehealth solutions by delivering high-quality, patient-centered virtual care across Pennsylvania. Manage diverse clinical cases while enjoying a flexible schedule that promotes w...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K *

Lead the charge in delivering high-quality virtual care as a board-certified physician, managing diverse clinical cases through innovative telemedicine solutions while enjoying a flexible schedule tha...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$270K - $280K *

Join a team that's driving clinical excellence by overseeing trial execution, managing timelines, budgets, and CROs. Collaborate with stakeholders to ensure compliance and quality while mentoring team...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$240K *

Shape the future of healthcare by delivering comprehensive outpatient family medicine, managing chronic conditions, and collaborating with subspecialties in a supportive environment focused on patient...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$174K - $374K *

Engage with patients in their homes to conduct health evaluations, build relationships, and bridge care gaps. This role demands extensive travel and flexibility to provide personalized care and diagno...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $215K *

Accelerate progress at a leading dental sales organization by managing a team of Territory Managers, driving sales strategies, and fostering collaboration across functions to achieve revenue targets a...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Lead the charge in delivering compassionate psychiatric care through comprehensive evaluation, diagnosis, and treatment, while collaborating with healthcare professionals and supervising psychiatric n...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$200K - $280K *

Shape the future of patient care by joining a dedicated team of internal medicine providers, delivering compassionate care in long-term and assisted living settings while collaborating across faciliti...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K *

Unlock potential by joining a dynamic telemedicine team, providing high-quality virtual care across Pennsylvania. Enjoy flexible scheduling while managing diverse clinical cases, from primary care to...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K *

Transform virtual healthcare by delivering compassionate, patient-centered care across Pennsylvania. Manage diverse clinical cases through secure telehealth consultations while enjoying a flexible sch...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K *

Unlock potential by delivering high-quality virtual care as a board-certified Family Medicine physician. Manage diverse clinical cases through telehealth, ensuring patient-centered treatment while enj...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K *

Elevate your career by joining a dynamic telemedicine team, providing high-quality virtual care across Pennsylvania. Manage diverse clinical cases while enjoying a flexible schedule that promotes work...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Support operational and financial oversight of physician practices, enhancing efficiency and productivity. Drive strategic planning, manage key metrics, and ensure compliance while fostering collabora...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.