Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Dentist Jobs in Mississippi

Sort By: Relevance

$78K - $106K *

Transform client payment policies by ensuring accuracy and compliance. Engage with internal and external teams to manage medical policy updates, conduct analyses, and enhance client relationships whil...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$99K - $136K *

Join a dynamic team as a strategic growth architect, driving revenue and market share expansion in the Hemostasis portfolio. Leverage your expertise in complex healthcare sales to influence decision-m...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $215K *

Drive regional success by leading launch execution and building high-performing teams. Foster customer relationships and ensure alignment with corporate goals in a fast-paced, entrepreneurial environm...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Transform innovative protein design through advanced AI techniques, enhancing antibody drug discovery. Collaborate across disciplines to maximize efficiency and impact, while leading research that set...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $120K *

Transform healthcare systems by analyzing data, leading client engagements, and implementing performance improvements. Collaborate with a skilled team to deliver actionable insights and drive meaningf...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$98K - $138K *

Partner with us to implement advanced Appian solutions, guiding clients through design and integration while enhancing internal processes. Leverage your expertise to drive technical success and mentor...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$222K - $292K *

Elevate patient outcomes by leading global evidence strategies that showcase the value of therapies. Collaborate across functions to drive research programs, influence decision-making, and ensure scie...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$145K - $190K *

Join a team that's dedicated to supporting educational institutions by providing expert legal counsel on governance, compliance, and operational matters. Collaborate with public entities to navigate c...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$192K - $303K *

Empower innovation as you lead the strategy and development of core platform primitives, driving the future of agentic systems and ensuring product teams can rapidly create and deploy advanced agents...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$105K - $127K *

Champion growth by driving enterprise sales in healthcare payors, leveraging SaaS solutions to enhance client experiences. Build relationships, negotiate contracts, and exceed quotas while collaborati...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $135K *

Unlock potential by managing complex cost management services for major corporate real estate projects. Support large-scale workplace developments, vendor negotiations, and financial reporting to deli...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $130K *

Advance the adoption of cutting-edge prostate cancer imaging solutions while leading site activations, enhancing workflows, and ensuring optimal product utilization in the oncology sector, supporting...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$54K - $155K *

Join a team that's transforming mental health delivery through innovative, tech-enabled solutions. Provide 24/7 support via video, chat, or phone, ensuring timely access to high-quality mental health...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$181K - $301K *

Elevate our cyber defense capabilities by architecting advanced detection and response systems. Lead cross-functional initiatives, influence technical strategy, and enhance security measures to protec...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$100K - $120K *

Join a team that's dedicated to ensuring financial integrity and compliance. In this hands-on role, you'll manage revenue recognition and accounting processes, collaborating across departments to supp...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$143K - $243K *

Champion innovative clinical strategies in specialty pharmacy, overseeing services and solutions to enhance client value and outcomes. Collaborate with cross-functional teams to drive program performa...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$81K - $142K *

Lead the design and development of enterprise data management solutions, collaborating with stakeholders to analyze requirements and enhance data processing capabilities using advanced technologies in...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$92K - $126K *

Drive innovative solutions by blending product analytics and low-code development, collaborating cross-functionally to enhance AI Agent capabilities and optimize Revenue Cycle operations within the he...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$185K - $210K *

Engage with clients to drive retention and growth strategies, fostering deep relationships and collaboration across teams. Leverage market insights to enhance product offerings and ensure client succe...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $225K *

Pioneer innovative research strategies to enhance clinical outcomes and drive impactful insights through collaboration across teams, while establishing a robust research infrastructure and publication...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $210K *

Elevate creative excellence by leading a multidisciplinary team, setting vision and quality standards, and driving impactful brand strategies across diverse channels in a dynamic healthcare environmen...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $214K *

Join a team that's redefining healthcare product management through innovative supply chain solutions. Lead cross-functional initiatives and shape the future of resilience in healthcare with strategic...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$69K - $105K *

Elevate your research career by conducting impactful studies that enhance crisis services. Collaborate with experts to analyze data, develop tools, and contribute to vital evaluations that support the...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $147K *

Shape your career by leading data integration initiatives that drive enterprise-wide consistency and governance. Collaborate with stakeholders to deliver trusted, scalable data products while ensuring...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $130K *

Develop and implement business rules for credit strategy, collaborating with Risk, Compliance, and Tech teams. Ensure accurate decision logic, maintain documentation, and support testing for optimized...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.