Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$252K - $315K *

Drive innovation in interventional psychiatry by developing evidence-based programs and protocols. Collaborate with clinical teams to enhance patient outcomes and ensure compliance with regulatory sta...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Unlock growth potential by managing strategic accounts and cultivating executive relationships. Drive revenue through tailored strategies and consultative selling, while aligning cross-functional team...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$75K - $158K *

Join our team as an SAP EHS Dangerous Goods Specialist, where you'll lead the configuration and support of critical processes, ensuring compliance with global regulations while collaborating across fu...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $180K *

Lead strategic health plan implementations and optimize client solutions. Drive cross-functional collaboration, manage complex projects, and enhance operational workflows to ensure successful launches...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $300K *

Oversee and deliver exceptional diagnostic imaging services remotely, focusing on evening shifts. Collaborate within a dynamic team while managing varied inpatient and outpatient cases to support pati...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Join a team that's dedicated to building lasting client relationships while managing accounts and delivering tailored pest management solutions. Leverage your communication skills to drive sales and e...

Today

  •   Less than 5 years exp.  •   Staffing

$80K - $100K *

Drive client relationships and sales growth by managing accounts, conducting inspections, and delivering tailored pest management solutions. Leverage industry expertise and tools to ensure customer sa...

2 days ago

  •   Less than 5 years exp.  •   Staffing

$72K - $94K *

Transform patient access operations by leading centralized support functions, optimizing workflows, and enhancing service quality across multiple regions. Drive continuous improvement and develop lead...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$122K - $211K *

Join a dynamic team as a DevOps Engineer, enhancing cloud infrastructure and CI/CD pipelines. Collaborate with developers and cybersecurity experts to ensure reliable software delivery and operational...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$245K - $265K *

Optimize partnerships with Medical Experts to enhance neurology care. Drive strategic insights and educational initiatives while collaborating across teams to influence business decisions and improve...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$175K - $251K *

Lead the charge in transforming customer experiences through innovative cloud security solutions, leveraging your expertise to craft tailored technical presentations and solutions that drive strategic...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$185K - $205K *

Shape the future of customer success by leading complex SaaS solutions, driving strategic partnerships, and mentoring teams to enhance value delivery and accelerate growth across enterprise accounts...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$200K - $240K *

Drive strategic growth initiatives for Navy & Marine Corps, leading business development efforts and fostering partnerships to enhance tactical networking solutions across diverse operational domains...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$140K - $153K *

Join a team that's dedicated to enhancing healthcare quality through innovative testing strategies. Collaborate with cross-functional teams to ensure robust, user-centered products while mentoring jun...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $105K *

Collaborate with clients to enhance their social media strategies using healthcare insights, data-driven execution, and creative content development for multi-channel success. This role demands a proa...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Innovate user experiences by leveraging AI tools to enhance design processes, ensuring intuitive and accessible digital solutions. Collaborate with cross-functional teams to drive strategic UX initiat...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$75K - $95K *

Unlock potential by navigating complex transportation claims with expertise, ensuring resolution while collaborating with clients, attorneys, and medical providers to uphold regulatory standards in a...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$82K - $137K *

Transform business insights into actionable data solutions by collaborating with stakeholders, analyzing data quality, and ensuring effective integration of analytical products to drive operational ef...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$86K - $118K *

Lead the charge in managing complex healthcare projects, ensuring timely delivery and budget adherence while coordinating cross-functional teams and mitigating risks for strategic initiatives...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $100K *

Join a dynamic team to drive the implementation of innovative service lines, enhancing clinician and patient experiences. Collaborate cross-functionally to optimize operations and lead initiatives tha...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in transforming complex revenue-cycle challenges into robust, production-ready AI models, ensuring statistical integrity and operational reliability while managing end-to-end data pipe...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in driving regional sales growth by developing strategic plans, managing budgets, and fostering strong customer relationships. Collaborate with cross-functional teams to optimize perfo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Unlock potential by leading a global team in Trust Services, enhancing client relationships, and driving operational excellence. Shape the future of AI-powered security solutions while ensuring top-ti...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $120K *

Support a national patient community by providing critical therapy coverage across multiple states, ensuring continuity of care during clinician absences. Collaborate with multidisciplinary teams to d...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$224K - $326K *

Serve as a technical leader for large customers, guiding AI cloud strategies. Connect business priorities with scalable architecture while managing executive engagements and navigating complex decisio...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.