Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$112K - $132K *

Join a team that's shaping the future of autism care by building robust statistical methodologies. You'll analyze real-world clinical data, ensuring rigorous evaluation of outcomes and social validity...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$252K - $315K *

Champion psychiatric practice excellence by developing standards and frameworks, enhancing clinician support, and driving quality improvement initiatives to elevate patient outcomes and operational ef...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Transform credentialing operations by leading a dedicated team to ensure compliance, enhance efficiency, and support provider network growth through strategic oversight and process improvement initiat...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$68K - $116K *

Join a dynamic team to lead clinic operations, enhance patient care, and foster employee development. Drive quality outcomes while utilizing innovative AI technology to streamline documentation and im...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $115K *

Lead the charge in managing high-exposure General Liability claims, developing strategies for resolution, and collaborating with clients and legal teams to deliver exceptional service in a dynamic, su...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$104K - $187K *

Empower your career by leading privacy initiatives in a dynamic, regulated environment. Collaborate with cross-functional teams to enhance privacy practices, ensuring compliance and ethical use of per...

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$104K - $187K *

Champion privacy initiatives by serving as a key consultant and partner across teams, ensuring compliance and ethical use of personal information in a complex regulatory environment. Drive privacy mat...

Des Moines, IARemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$140K - $175K *

Empower Apollo's frontier partnerships by deepening collaborations with AI-native platforms and foundation model companies. Analyze the evolving landscape and drive monetization strategies while build...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$139K - $222K *

Join a team that's shaping the future of housing market forecasting. Collaborate with experts to develop innovative models, extract key features, and communicate insights that drive strategic decision...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$125K - $150K *

Lead the development and execution of a comprehensive People strategy, enhancing operational readiness and employee experience across a complex, multi-site workforce while driving sustainable growth a...

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$130K - $140K *

Empower healthcare providers by promoting innovative colorectal cancer screening solutions, delivering exceptional support and education while strategically expanding product adoption across a designa...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Transform client marketing strategies by leading integrated campaigns, translating data into actionable insights, and driving measurable results. Collaborate cross-functionally while mentoring junior...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$68K - $93K *

Join a team that's dedicated to driving sales and enhancing customer relationships in the animal health sector. Utilize innovative strategies and digital tools to maximize performance and deliver exce...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$104K - $130K *

Empower growth by transforming complex data into actionable insights. Collaborate with senior leaders to build analytical tools and models that drive strategic decisions, while enhancing operational e...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Transform enterprise learning by leading a team to design impactful solutions. Drive employee development, align training with business goals, and optimize learning technologies for enhanced performan...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$153K - $290K *

Transform drug discovery by leading a dynamic team in medicinal chemistry, driving innovative small-molecule candidates from concept to IND-ready status while fostering collaboration across a global n...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$210K - $230K *

Lead the charge in developing enterprise pricing strategies that optimize profitability and drive growth across diverse service sectors, ensuring alignment with market conditions and client needs whil...

RemoteRemote

3 days ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$78K - $168K *

Drive health outcomes by conducting in-home evaluations, building trust with patients, and providing personalized care. Travel extensively to meet diverse needs, ensuring comprehensive health assessme...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$204K - $229K *

Empower a dynamic consulting team by driving growth strategies, securing projects, and fostering client relationships. Lead initiatives in civic innovation and mobility while mentoring talent and enha...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$240K - $330K *

Pioneer growth in the healthcare sector by driving new business and cultivating strong client relationships. Utilize expert sales skills to oversee complex deals from prospecting to closing in a consu...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$113K - $188K *

Champion adolescent health initiatives by providing strategic guidance and support to federal agencies, enhancing youth engagement, and implementing evidence-based programs to improve outcomes for ado...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Lead the charge in overseeing the Process Safety Management and Dust Hazard Analysis programs, ensuring compliance and facilitating audits while collaborating with various departments to enhance safet...

2 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$80K - $92K *

Drive the resolution of technical support escalations as a key Tier 2 expert, leveraging your skills to troubleshoot issues, foster collaboration within teams, and enhance workflows in a dynamic envir...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Technical Services

$111K - $167K *

Join a team that's driving healthcare transformation by leading client integration initiatives. Collaborate across departments to ensure seamless transitions, operational readiness, and long-term succ...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$117K - $160K *

Lead the charge in underwriting E&S commercial property and casualty accounts. Manage risk assessments, develop competitive quotes, and collaborate with carriers to optimize profitability while achiev...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.