Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$120K - $130K *

Partner with us to drive product innovation and marketing strategies across dietary supplements and topical hair care. Collaborate with cross-functional teams to launch new products, ensuring alignmen...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$92K - $167K *

Drive compliance and contractor support in contracting standards, regulatory adherence, and policy execution. Work collaboratively across departments to provide strategic guidance, ensuring alignment...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$179K - $280K *

Unlock potential by driving strategic revenue cycle performance and enhancing client partnerships. Lead initiatives across Self-Pay and Patient Financial Experience, leveraging data to influence decis...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$155K - $195K *

Manage the transformation of Customer Support into a strategic function, driving operational efficiency and enhancing service quality. Lead a team to implement innovative strategies that elevate the c...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the charge in clinical study start-up operations, driving team development and ensuring timely site activation. Collaborate cross-functionally to enhance processes, meet regulatory standards, and...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$79K - $139K *

Join a team that's dedicated to driving excellence in clinical trial contracts. As a Senior Site Contracts Manager, you'll negotiate and manage site budgets and agreements, collaborating with key stak...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$162K - $292K *

Join a team that's redefining identity operations by leading a 24/7 team to enhance access management strategies. You'll shape the vision, drive process innovation, and foster talent in a collaborativ...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$115K - $120K *

Help us support individuals, couples, and families through effective therapy, addressing communication issues and relationship dynamics while maintaining clinical records and ensuring client confident...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Transform the lives of individuals, couples, and families by providing virtual therapy, addressing communication issues, and fostering healthier relationships while managing clinical records and refer...

Ames, IARemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Join a team that's dedicated to delivering high-quality telehealth therapy, supporting clients through relationship and personal challenges. Enjoy a consistent schedule and competitive compensation wh...

Ankeny, IARemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Unlock potential by providing high-quality telehealth therapy to individuals, couples, and families. Collaborate with clients to navigate relationship dynamics and personal challenges in a supportive...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$123K - $172K *

Join our dynamic team to tackle real challenges in SaaS management, enhancing IT and Security ecosystems. Collaborate with talented professionals to build impactful software while leveraging AI for ef...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Lead cross-functional teams to develop and execute a strategic product roadmap, integrating market insights and performance metrics to drive customer-centric solutions in the diagnostics and genomics...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$115K - $125K *

Grow your career with a dynamic role focused on client relationships, strategic account management, and operational excellence. Collaborate with cross-functional teams to ensure client satisfaction an...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$68K - $93K *

Drive sales growth by developing relationships with veterinary practices, utilizing digital marketing and CRM tools to enhance customer engagement and achieve sales targets in a dynamic inside sales e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Champion customer relationships and drive sales growth in the dairy nutrition sector. Engage with clients through face-to-face and remote interactions, leveraging your expertise to optimize animal hea...

Today

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $115K *

Champion digital success by advising dealers on marketing strategies, analyzing performance metrics, and providing consultative services to enhance sales and service operations. Drive measurable impro...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Media

$60K - $200K *

Lead the charge in roofing sales by leveraging your expertise in exterior restoration. Engage with homeowners, assess needs, and drive projects from inspection to closure while utilizing company resou...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$70K - $200K *

Explore your potential in roofing sales by leveraging your industry expertise. Engage with homeowners, assess their needs, and drive projects to completion while building lasting relationships in a dy...

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$70K - $200K *

Drive growth by leveraging your roofing sales expertise to assess and meet homeowner needs, managing relationships through project completion while expertly presenting tailored solutions and maintaini...

1 month ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$125K - $150K *

Champion the evolution of identity security by leading product management for our core identity graph and correlation services, ensuring seamless integration and access control across platforms while...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $120K *

Advance your career by implementing innovative SaaS solutions, configuring custom workflows, and driving system integration projects. Collaborate with a dynamic team to tackle complex challenges and d...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$175K - $200K *

Drive strategic medical initiatives in Rare Neurology, collaborating with cross-functional teams to enhance patient outcomes. Leverage your expertise to shape launch strategies and foster relationship...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$96K - $133K *

Support our cyber defense initiatives by leading incident response efforts, analyzing security events, and optimizing detection capabilities to enhance network security and protect sensitive data...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by joining a dynamic Clinical Oncology Team, where you'll leverage your oncology and genomics expertise to enhance point-of-care products, drive clinical workflows, and support person...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.