Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$186K - $218K *

Architect robust security solutions to safeguard corporate infrastructure and user devices. Collaborate with IT and engineering teams to identify risks and implement effective security measures, ensur...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$165K - $180K *

Transform your career by driving new customer acquisition in healthcare. Leverage your expertise to build C-suite relationships and lead complex sales processes, contributing to the growth of a dynami...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Technical Services

$156K - $187K *

Transform the data landscape by designing and implementing robust integration solutions. Collaborate with cross-functional teams to enhance analytics infrastructure, ensuring seamless data flow and go...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Lead the end-to-end recruiting process, enhancing strategies and partnerships across departments. Drive high-volume hiring with autonomy, ensuring a seamless candidate experience while collaborating c...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $160K *

Contribute to the evolution of data-driven healthcare products, shaping strategy and execution. Collaborate with cross-functional teams to deliver AI-enabled solutions that enhance clinical outcomes a...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $180K *

Empower growth in healthcare by expanding product use and training staff. Collaborate across teams to launch innovations and build valuable relationships, enhancing critical care capabilities in your...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $138K *

Manage regional meetings and events, ensuring seamless execution and compliance. Oversee budgets, vendor relationships, and logistics while collaborating with cross-functional teams to meet organizati...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K *

Elevate Medicaid partnerships by driving strategic sales initiatives, securing contracts, and fostering client relationships. Lead a team to achieve growth targets while navigating market dynamics and...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$184K - $230K *

Shape the future of product security by leading architecture reviews and risk mitigation strategies. Collaborate with engineering and compliance teams to embed security throughout the development life...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$192K - $334K *

Tackle complex healthcare M&A engagements, leading due diligence efforts, and collaborating with clients and teams to drive value. Manage multiple projects while utilizing your expertise to influence...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$155K - $203K *

Elevate your career by joining our team as a Workers' Compensation Defense Attorney, where you'll manage litigation cases, provide legal counsel, and collaborate with clients to achieve favorable outc...

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$170K - $200K *

Unlock potential by designing and building innovative billing systems that simplify financial transactions and maximize reimbursements, while leveraging AI to enhance efficiency and user experience in...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$220K - $260K *

Drive credit and fraud strategy for a lending business. Lead a high-performing team, manage risk and profitability, and partner with executives and stakeholders to achieve strategic objectives and dev...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$119K - $179K *

Lead the charge in architecting FHIR-compliant data models to enhance clinical data integration and usability, supporting patient care and research initiatives across the organization...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$159K - $235K *

Champion advanced detection engineering to enhance threat identification capabilities. Collaborate with Protective Services to develop and optimize detection systems, integrating diverse data sources...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$100K - $115K *

Build strong client partnerships and drive growth by managing a portfolio of mid-sized employers. Collaborate cross-functionally to enhance engagement, retention, and revenue while delivering data-dri...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$104K - $143K *

Deliver impactful reporting solutions by translating measurement needs into actionable requirements, managing backlogs, and collaborating with cross-functional teams to ensure effective execution and...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Drive sustained growth as a key commercial leader by executing innovative revenue strategies, generating new client opportunities, and expanding market presence in the evolving data center and AI infr...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$180K - $220K *

Drive strategic client engagement and business development within assigned territories, fostering relationships with C-level executives in the legal sector to enhance growth and establish trust in tai...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Empower pre-sales excellence by serving as a strategic technical advisor, enhancing internal teams and client outcomes through solution demonstrations, enablement programs, and collaboration across sa...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Pioneer data-driven growth strategies to enhance subscription revenue through analytics, experimentation, and automation. Collaborate cross-functionally to implement impactful changes across acquisiti...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Hospitality & Recreation

$112K - $188K *

Transform customer experiences by leading strategic analytics initiatives that drive operational efficiency and enhance associate capabilities. Collaborate with leadership to develop insights and infl...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Drive growth by promoting innovative regenerative medicine solutions. Leverage your expertise in vascular surgery sales and establish strong customer relationships to achieve targets and make a meanin...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Accelerate progress at the forefront of cybersecurity sales, engaging enterprise accounts to drive growth, cultivate strategic partnerships, and dominate the market with innovative solutions that secu...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$168K - $245K *

Elevate user experiences as a Senior Product Designer, crafting intuitive mobile and web solutions. Collaborate with cross-functional teams to balance speed and quality, driving engagement and retenti...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.