Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$210K - $250K *

Innovate in AI-native primary care by leading a dynamic medical group. Manage physicians, enhance care delivery, and shape clinical programs while maintaining direct patient care involvement. Drive ex...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$162K - $224K *

Drive growth in the Neurodegenerative Disease sector by developing strategic partnerships with health systems and academic centers, leveraging existing relationships to create innovative solutions tha...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Empower your career by serving as a legal partner in procurement and supply chain, providing expert guidance and support in contract negotiation, vendor relations, and operational risk management acro...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$82K - $137K *

Join a team that's dedicated to enhancing client relationships and service delivery. You'll manage client needs, collaborate with internal teams, and analyze data to drive satisfaction and performance...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$192K - $278K *

Support the development and leadership of a security incident response team, focusing on enhancing automation, program maturity, and cross-functional collaboration to ensure effective incident managem...

RemoteRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$131K - $240K *

Shape the future of training and development in orthopedic medical devices, enhancing sales effectiveness and fostering strong partnerships across teams. Drive learning initiatives and support surgica...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$210K - $250K *

Unlock potential by leveraging your GI expertise to enhance product development, strengthen customer relationships, and drive growth in a dynamic SaaS environment. Collaborate across teams to deliver...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$74K - $87K *

Unlock patient access by managing the insurance verification process, addressing barriers to care, and ensuring seamless coordination among stakeholders to facilitate timely therapy access and support...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Collaborate with healthcare providers to drive commercial performance and product adoption. Engage in territory business planning, support product launches, and optimize patient access to innovative t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $145K *

Engage in the development and delivery of innovative training programs that enhance the skills and performance of sales teams in the pharma/biotech sector, ensuring alignment with strategic goals and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by owning the end-to-end product surface, driving discovery, design, and migration while collaborating closely with users to solve real market problems in a dynamic healthcare environ...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$230K - $280K *

Lead a high-performing team to enhance Solutions Consulting, drive cross-functional collaboration and ensure the success of strategic accounts through innovative, accountable deal execution and contin...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$152K - $179K *

Develop and implement security solutions to protect corporate infrastructure, user devices, and applications. Collaborate with IT and engineering teams to identify risks and enhance security measures...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$84K - $87K *

Join us as a Data Operations Engineer, where you'll develop and manage data systems for healthcare claims processing. Collaborate with teams to ensure data accuracy and optimize ETL/ELT pipelines whil...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$74K - $102K *

Explore and enhance HR systems by supporting configuration, maintenance, and improvements. Collaborate with stakeholders to resolve issues and drive system enhancements in a dynamic environment focuse...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$124K - $197K *

Drive excellence by overseeing 340b pharmacy services in a community health center, ensuring quality care for diverse patient populations while managing a dedicated team and optimizing pharmacy operat...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$250K - $280K *

Shape the future of our enterprise sales segment by driving growth and account success. Take ownership of new logo acquisitions, deepen existing client relationships, and establish best practices for...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Champion the delivery of exceptional nursing services by overseeing operations, managing staff, and ensuring compliance with regulations while fostering a collaborative environment to enhance patient...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to delivering exceptional nursing services while overseeing operations and ensuring compliance with regulations. Collaborate with clinical staff to enhance patient care an...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $150K *

Drive reputation management and consumer insights initiatives, enhancing brand trust and informing strategic decisions. Collaborate across teams to analyze data, identify trends, and improve consumer...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$129K - $185K *

Innovate global medical strategies for the Companion Animal Pain portfolio, driving growth and customer value through scientific engagement, KOL collaboration, and effective market implementation acro...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$103K - $128K *

Join us to lead product strategy and development, driving innovation and performance in healthcare solutions. Collaborate cross-functionally to align business needs with customer expectations and ensu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$112K - $193K *

Transform pharmacy operations by enhancing consumer experiences, mentoring staff, and ensuring compliance. Lead financial growth while promoting quality health services and building strong community r...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$149K - $206K *

Empower your career by delivering exceptional virtual care as you evaluate and treat diverse patient needs, ensuring optimal outcomes through collaboration and quality measures in a dynamic team envir...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$73K - $115K *

Grow your career with a dynamic team focused on optimizing provider operations. Lead credentialing initiatives, implement AI solutions, and enhance workflows while ensuring compliance and operational...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.