Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$200K *

Transform the landscape of life sciences partnerships by driving co-developed deals. Leverage your extensive network and expertise to source, pitch, and close high-value agreements that enhance patien...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$100K - $120K *

Empower a dedicated team to enhance the quality of life for residents in an assisted living community. Lead operations, ensure compliance, and foster a supportive environment while driving excellence...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Accelerate commercial growth by defining strategies for product families, collaborating across teams to translate market insights into actionable plans that drive revenue, profitability, and customer...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Healthcare

$100K - $122K *

Take ownership of financial planning and analysis for G&A expenses, driving insights and reporting for senior leadership. Collaborate with teams to enhance budgeting, forecasting, and variance analysi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Unlock your potential by analyzing Medicaid data to enhance program performance, quality, and access. Collaborate with diverse teams to develop insights that drive impactful decisions in healthcare an...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$180K - $215K *

Elevate regional sales performance by leading a high-impact team, executing strategic launches, and fostering key customer relationships in a dynamic, fast-paced environment. Drive accountability and...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $144K *

Optimize our data platform by owning end-to-end data engineering projects, leveraging AI coding agents, and ensuring data quality. Collaborate with cross-functional teams to deliver reliable, maintain...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Shape the future of surgical care by coordinating clinical operations for multiple service lines, ensuring readiness and collaboration among teams to deliver safe, efficient, and high-quality patient...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$96K - $144K *

Lead the charge in delivering exceptional customer service and technical support at assigned medical equipment sites, ensuring compliance with contracts and fostering strong client relationships throu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Optimize patient care by ensuring accurate medication dispensing and compliance. Collaborate with healthcare teams to provide clinical guidance and maintain high standards in a dynamic pharmacy enviro...

Today

  •   Less than 5 years exp.  •   Healthcare

$68K - $93K *

Join a team that's dedicated to driving sales in the pet health sector. You'll build relationships with veterinary practices, leverage digital tools, and execute strategies to maximize sales performan...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$143K *

Join a team that's redefining virtual healthcare by delivering high-quality, patient-centered care. As a key member, you'll provide comprehensive virtual medical services, collaborate with stakeholder...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$95K - $105K *

Collaborate with us to manage federal government contracts, ensuring compliance and effective execution throughout the contracting lifecycle. Support proposal development, contract administration, and...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Staffing

$110K - $130K *

Champion client success by managing key relationships and driving strategic initiatives. Lead cross-functional teams to deliver high-quality work while ensuring financial performance and growth for as...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Optimize regulatory compliance and legal operations in healthcare. Collaborate with cross-functional teams to ensure adherence to industry standards while driving efficiency and effectiveness in legal...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$81K - $122K *

Join a dynamic team to support M&A activities through financial analysis, market research, and transaction coordination. Develop expertise in valuation concepts and contribute to deal documentation an...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$113K - $197K *

Drive automation and AI initiatives in claims operations, enhancing efficiency and accuracy. Lead a team to optimize workflows, manage vendor performance, and ensure compliance while delivering measur...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$250K - $300K *

Champion a dynamic Emergency Medicine team, overseeing clinical and administrative functions while enhancing patient care in a collaborative environment. Drive excellence in a community-focused settin...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Unlock your potential as you empower deployment and automation solutions in high-security environments. Leverage your expertise in DevOps and platform engineering to ensure robust operations across fe...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a dedicated team as a Clinical Pharmacist, ensuring safe and effective medication therapy while collaborating with healthcare professionals to enhance patient outcomes and streamline pharmacy ope...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive the success of insurance prior authorization processes by leading a team of specialists. Ensure timely approvals and minimize payment denials through effective management, communication, and pro...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$88K - $105K *

Join a team that's dedicated to delivering exceptional client service and operational excellence. As a Program Manager, you'll oversee program execution, account management, and financial oversight wh...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive customer support excellence by managing a frontline team to ensure timely resolutions, operational efficiency, and a culture of continuous improvement, paving the way for stellar service in heal...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$70K - $180K *

Drive impactful healthcare technology solutions through data-driven strategies, optimize customer engagements with compelling insights, and foster long-term partnerships for strategic growth...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $200K *

Lead the development of a robust risk and control framework, ensuring effective identification and management of risks in fiduciary and regulated financial services. Collaborate with stakeholders to e...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.