Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$180K - $220K *

Advance your career by providing comprehensive primary care in a supportive, team-oriented rural clinic. Enjoy a diverse patient population and utilize innovative tools to enhance work-life balance wh...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$115K - $140K *

Join a team that's shaping compelling narratives across diverse marketing channels. You'll craft engaging copy for digital ads, emails, and more, collaborating closely with various departments to enha...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$265K - $300K *

Shape the future of neurodegenerative disease diagnostics by leading scientific strategy, driving research programs, and building expert networks to establish industry leadership in innovative solutio...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Business Services

$67K - $111K *

Elevate your career by providing critical analysis and programming support for application software, ensuring a comprehensive and integrated information network that meets diverse customer needs and e...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$73K - $100K *

Transform patient care by evaluating and treating diverse conditions in an outpatient setting. Collaborate with a dedicated team to enhance recovery and improve quality of life while enjoying a suppor...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$123K - $172K *

Build and maintain user-friendly administrative interfaces for enterprise customers, enhancing device security management. Collaborate with cross-functional teams to develop scalable solutions and con...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $200K *

Drive strategic growth and business development for National Accounts in Urology and Oncology, optimizing resources and leading negotiations to enhance healthcare outcomes through innovative diagnosti...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive innovative design solutions that elevate brand identity across diverse media. Collaborate with cross-functional teams to create impactful visual assets, ensuring consistency and clarity in commu...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Drive new business growth by owning the full sales cycle in the mid-market segment. Leverage your expertise in cybersecurity solutions to maximize revenue and collaborate cross-functionally to achieve...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $100K *

Unlock potential by managing complex claims with a focus on legal inquiries and resolutions. Collaborate with clients and experts to deliver innovative solutions while enjoying flexibility and profess...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$238K - $357K *

Transform growth strategies by leading AI initiatives, targeting key customers, and driving adoption through innovative partnerships and market insights. Collaborate across teams to enhance product of...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$174K - $374K *

Unlock potential by leading medical management initiatives remotely, supporting member needs and optimizing clinical services for optimal care. Leverage your expertise in Orthopedic Spine or Neurosurg...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $123K *

Champion the technical SEO landscape to enhance site performance, drive conversions, and establish authority across diverse audiences. Collaborate with engineering teams to implement solutions and opt...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$219K - $277K *

Elevate community oncology practices by driving growth and retention through strategic sales initiatives. Collaborate with cross-functional teams to enhance market presence and deliver tailored soluti...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$90K - $110K *

Transform workplace health by leading multiple occupational health clinics. Drive operational excellence, foster client relationships, and enhance team performance while ensuring exceptional patient c...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead the nursing department to ensure exceptional care, fostering a supportive environment while guiding clinical practices and team development. Drive continuous improvement and compliance with regul...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$149K - $202K *

Make your mark at the forefront of patient access marketing, leading strategies and initiatives to enhance the Bone portfolio experience. Collaborate cross-functionally to optimize access solutions an...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $114K *

Engage in leading the Nursing department, ensuring high-quality care and compliance with regulations. Collaborate with staff to foster a supportive environment, guiding clinical practices and promotin...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$125K - $150K *

Optimize reimbursement strategies and regulatory compliance by leading analysis, developing policies, and mentoring teams. Drive operational excellence and foster relationships with stakeholders to en...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Lead the charge in driving scalable revenue growth through integrated demand generation and digital marketing strategies. Collaborate with cross-functional teams to optimize marketing operations and e...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$133K - $237K *

Contribute to patient safety by overseeing medical product surveillance, analyzing data, and ensuring compliance with regulations. Collaborate on risk management and support clinical studies to enhanc...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Transform healthcare through innovative AI deployments. As a key technical expert, you'll develop and implement cutting-edge systems that enhance clinical workflows and optimize patient interactions...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$280K - $340K *

Transform regulatory strategy and operations across CMC and clinical activities, leading a high-performing team to ensure compliance and successful product approvals from development through post-appr...

United StatesRemote

3 weeks ago

  •   15+ years exp.  •   Information Technology

$349K - $396K *

Lead the charge in driving national growth strategies for enterprise employers, managing a top-performing sales team focused on Fortune 500 engagements, overseeing the acquisition lifecycle, and ensur...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $96K *

Empower homeowners by creating tailored Smart Security solutions. Engage with customers directly, providing expert installation and support while enjoying uncapped commission opportunities in a dynami...

2 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.