Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$150K - $180K *

Elevate oncology operations by providing strategic leadership, enhancing patient care, and ensuring regulatory compliance. Collaborate with clinical leaders to drive efficiency, growth, and quality ou...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Elevate nursing leadership by driving workforce development, enhancing operational excellence, and fostering a culture of quality and service. Collaborate with nurse leaders to support onboarding, coa...

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Lead the charge in medical oversight, providing guidance and compliance support within healthcare settings. Collaborate with personnel to enhance patient outcomes and ensure adherence to policies and...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Transform patient safety and risk management by leading initiatives that enhance quality care and compliance across the region. Collaborate with healthcare leaders to drive improvements and ensure a s...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$103K - $134K *

Lead strategic compliance initiatives to ensure adherence to conflict of interest regulations. Oversee training, disclosure processes, and institutional policies while fostering transparency and integ...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in transforming nursing services by overseeing operations, enhancing patient care, and integrating interdisciplinary practices across multiple sites, ensuring compliance and quality im...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $100K *

Shape the future of surgical care by leading nursing practices, ensuring high standards, and enhancing patient outcomes in the operating room. Collaborate with a dedicated team to drive performance im...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $300K *

Transform operational excellence by leading multi-location legal operations, optimizing processes, and driving profitability. Collaborate with executives to enhance performance metrics and ensure seam...

Yesterday

  •   8 - 10 years exp.  •   Legal & Accounting

$80K - $95K *

Transform care coordination by leading strategic initiatives and overseeing case management services. Collaborate with senior leadership to ensure compliance, quality, and effective program developmen...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$272K - $336K *

Transform your career by leading clinical strategy in enzyme replacement therapies. Collaborate across teams and engage with experts to drive innovative solutions in neurology and rare disease drug de...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$206K - $350K *

Drive clinical excellence as you lead medical management functions, ensuring high-quality, cost-effective care. Collaborate with diverse teams to enhance member outcomes and compliance while fostering...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$266K - $340K *

Transform clinical development by leading innovative trials in immunology. Drive strategy, ensure patient safety, and collaborate with cross-functional teams to advance therapies for autoimmune diseas...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Lead the charge in advancing clinical revenue cycle management initiatives, ensuring accurate documentation and coding while driving performance improvements across diverse stakeholders to enhance rev...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Empower your career by joining a dynamic team focused on enhancing patient health outcomes through effective chronic care management and collaboration with multidisciplinary healthcare professionals...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Optimize patient care by overseeing medical services, supervising staff, and ensuring compliance with healthcare standards. Collaborate on quality improvement initiatives and manage emergency situatio...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Unlock your potential as a clinical leader, driving high-quality, patient-centered dental care while overseeing program goals, compliance, and workforce development in a dynamic healthcare environment...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Lead the advancement of high-quality, patient-centered dental care while overseeing clinical standards, quality improvement, and regulatory compliance. Collaborate with leaders to enhance operational...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$180K - $220K *

Transform behavioral health care by providing compassionate psychiatric evaluations, medication management, and support within a collaborative team. Engage with clients facing complex challenges in a...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$112K - $131K *

Drive compliance and quality initiatives as a leader in risk management, ensuring adherence to regulations while fostering a culture of safety and continuous improvement across the organization. Super...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Optimize patient care by leading nursing operations, ensuring quality standards, and fostering teamwork. Collaborate with management to enhance service delivery and support staff development for impro...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$133K - $180K *

Join a team that's redefining member experiences by architecting optimal journeys, bridging operational execution with strategic vision to enhance engagement and satisfaction across all touchpoints...

United StatesRemote

1 month ago

  •   11 - 15 years exp.  •   Healthcare

$69K - $114K *

Empower patient safety by leading initiatives that enhance compliance and risk management. Collaborate with diverse teams to foster a culture of safety and continuous improvement, ensuring optimal car...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$262K - $393K *

Join a team that's dedicated to optimizing clinical outcomes and quality performance through strategic non-acute utilization management. Collaborate with providers to enhance care delivery and drive v...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$82K - $107K *

Lead the charge in enhancing quality and compliance within healthcare operations. Oversee strategic initiatives, manage medical records, and ensure regulatory adherence while fostering a culture of co...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a dynamic team as a leader in patient care, driving operational excellence and empowering staff to enhance clinical outcomes while ensuring compliance and fiscal health in a fast-paced environmen...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.