Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$80K - $95K *

Engage in a leadership role overseeing professional coding operations, ensuring compliance and quality control. Collaborate with medical staff to enhance documentation and coding accuracy while managi...

Hyannis, MARemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$91K - $120K *

Join our dynamic Care Management team to enhance patient outcomes through effective care coordination. Leverage your clinical expertise in a person-centered approach, collaborating with healthcare tea...

California, USRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$113K - $169K *

Partner with us to deliver comprehensive in-home assessments for patients with complex needs, ensuring quality care and optimal health outcomes through collaboration with an interdisciplinary team in...

San Bernardino, CARemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$97K - $193K *

Join a dynamic team as a Senior CRA, ensuring high-quality clinical studies through expert oversight, proactive monitoring, and strong partnerships with sites and sponsors. Your leadership will drive...

Kansas, USRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Elevate operational excellence by leading claims operations, ensuring compliance and efficiency while driving process improvements and team development. Collaborate across functions to meet client com...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Lead the charge in financial strategy and operational excellence, driving growth and sustainability for a mission-driven organization. Collaborate with leadership to implement innovative solutions and...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$150K - $180K *

Transform financial operations by leading accounting initiatives, ensuring compliance, crafting technical accounting policies, and preparing accurate financial statements in a dynamic environment. Man...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$252K - $315K *

Champion psychiatric practice excellence by developing standards and frameworks to enhance clinician support, patient outcomes, and operational quality. Collaborate with leadership to implement eviden...

New York, NYRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$70K - $126K *

Unlock potential by leveraging comprehensive datasets to drive impactful business decisions. Collaborate with stakeholders to analyze trends, develop solutions, and improve clinical outcomes while man...

Florida, USRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $130K *

Champion customer success by designing and optimizing scalable programs that enhance adoption of identity security solutions, ensuring impactful training and resources for customer-facing teams...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Drive clinical excellence by overseeing virtual nursing operations, enhancing patient care through technology, and supporting staff development in a dynamic healthcare environment...

Cleveland, OHRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$107K - $199K *

Elevate your career by strategizing and implementing complex tech solutions. Lead project teams, conduct research, and mentor peers while driving operational excellence and stakeholder satisfaction in...

Missouri, USRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $251K *

Pioneer innovative technology strategies and architectural solutions across Agile teams, driving AI-enabled engineering transformation and ensuring scalable, secure, and maintainable solutions for ent...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Join a team that's revolutionizing enterprise architecture strategy, leading cross-disciplinary teams to align technology and business objectives. Drive innovation while ensuring compliance and qualit...

Chattanooga, TNRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Transform healthcare by providing tele-neurohospital medicine services. Collaborate with a dedicated team to enhance patient care through innovative virtual solutions, ensuring quality support and pro...

Nashville, TNRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Deliver comprehensive case reviews and clinical guidance, ensuring regulatory compliance and optimal patient outcomes. Collaborate with healthcare teams across multiple states to enhance service quali...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Unlock potential by leading comprehensive financial analysis and planning initiatives. Drive insights through data modeling and reporting, supporting strategic decision-making across multiple business...

Columbus, OHRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Drive reputation management and consumer insights initiatives, enhancing brand trust and informing strategic decisions. Collaborate across teams to analyze data, identify trends, and improve consumer...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Join a team that's shaping the future of CRM solutions, driving technical leadership and product strategy within the Salesforce ecosystem. Collaborate with cross-functional teams to enhance client por...

Philadelphia, PARemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive client success by managing relationships, enhancing satisfaction, and identifying growth opportunities. Collaborate with internal teams to deliver exceptional service and exceed client expectati...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $195K *

Empower patients by providing in-home assessments and care management. Collaborate with a multidisciplinary team to enhance health outcomes and prevent hospitalizations, ensuring timely clinical inter...

Santa Clara, CARemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Champion enterprise data architecture by establishing standards and a unified data catalog. Collaborate across teams to define metrics and ensure data governance, driving alignment and clarity in a ha...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$97K - $193K *

Drive excellence in clinical research as a Senior CRA, ensuring quality and compliance throughout the study lifecycle. Collaborate with sites and teams to enhance patient safety and data integrity, in...

Durham, NCRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$93K - $110K *

Accelerate your career by leading teams that enhance revenue cycle operations and provide exceptional support to clinicians. Drive quality, efficiency, and continuous improvement in eligibility verifi...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$136K - $214K *

Lead the charge in optimizing revenue operations by managing a dynamic team, enhancing forecasting processes, and ensuring data integrity across systems. Collaborate closely with sales leadership to d...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.