Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$80K - $99K *

Join a team that's shaping the future of medical education by providing strategic leadership and operational management for regional education initiatives, enhancing partnerships, and ensuring high-qu...

Kingston, ONRemote

4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Contribute to the success of multiple clinical research sites by leading operations, ensuring compliance with regulations, and fostering team development to enhance patient care and operational excell...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$174K - $374K *

Lead the charge in clinical oversight and mentorship, driving innovative medical solutions across diverse programs. Collaborate with cross-functional teams to ensure evidence-based decision-making and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Transform pharmacovigilance processes by leading compliance and quality initiatives, ensuring adherence to regulations while enhancing patient safety and product excellence across generics and biosimi...

Lehi, UTRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $160K *

Manage the delivery strategy for a critical telehealth product, ensuring alignment with VA goals. Collaborate with stakeholders and lead cross-functional teams to enhance virtual care for Veterans, dr...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Inspire data-driven decision-making as you lead analytics and predictive modeling efforts. Collaborate across teams to enhance patient engagement, forecast demand, and measure impact, driving strategi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Transform the communications landscape by building a dynamic team that drives brand relevance through strategic earned media, influencer relations, and corporate communications, ensuring a consumer-fi...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$97K - $193K *

Transform clinical research by managing site activities and ensuring compliance throughout the study lifecycle. Collaborate with teams to enhance patient safety and quality while supporting regulatory...

Durham, NCRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$67K - $134K *

Partner with us to enhance workplace wellness by developing and implementing strategies that improve employee health. This role involves client engagement, program design, and collaboration with inter...

Baltimore, MDRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Join a team that delivers high-quality telehealth psychotherapy to older adults. You'll design personalized treatment plans within a supportive environment, enjoy flexible hours, and benefit from dedi...

Florida, USRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$78K - $113K *

Join us to lead the Professional Coding Operations team, ensuring accurate coding practices and compliance. Collaborate with stakeholders, mentor staff, and drive improvements in coding efficiency and...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $110K *

Advance client partnerships by managing strategic initiatives, driving engagement, and optimizing healthcare solutions. Collaborate with internal teams to enhance service delivery and achieve clinical...

Missouri, USRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$203K - $245K *

Unlock potential by leading a national team of Thought Leader Liaisons to enhance KOL engagement and advocacy in oncology. Drive strategic initiatives, foster collaboration, and ensure compliance whil...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$210K - $275K *

Transform regulatory affairs in oncology by leading strategic submission initiatives and cross-functional collaborations, ensuring compliance and quality for impactful development programs. Drive regu...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $172K *

Join a team that's redefining healthcare innovation by collaborating with professionals to foster scientific knowledge, enhance patient outcomes, and drive product development initiatives through enga...

Texas, USRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive the charge in clinical research by managing site activities, ensuring compliance, and fostering relationships with site staff to support study objectives. Elevate patient safety and data integri...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Join a team that's pivotal in ensuring the integrity of clinical research. This role involves monitoring trial sites, ensuring compliance with regulations, and collaborating with teams to enhance clin...

Connecticut, USRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Drive growth in digital therapeutics by engaging medical practices, guiding them from initial interest to consistent orders. Collaborate with sales and clinical teams to shape the onboarding process a...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Shape complex, cross-functional programs that drive enterprise transformation, focusing on Customer Data Platform implementation and AI initiatives. Collaborate with diverse teams to ensure strategic...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $237K *

Join a team that fosters financial leadership and strategic excellence by providing key support to market leaders, ensuring transparent reporting, and driving business success through collaboration an...

New York, NYRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Transform client relationships by engaging with C-suite executives to drive strategic account growth. Collaborate on tailored solutions and industry insights, ensuring alignment with client goals and...

Mississauga, ONRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$100K - $120K *

Drive excellence in clinical operations by providing strategic oversight and support to enhance quality care in senior living communities. Collaborate with leadership to optimize resources, ensure com...

Brentwood, TNRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Elevate operational efficiency by leading shared service improvements and cross-functional collaboration to enhance patient and provider experiences while driving team performance and process excellen...

North Carolina, USRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Pioneer innovative strategies as a Medical Science Liaison, engaging with key opinion leaders and driving platform adoption. Collaborate across teams to translate clinical needs into actionable insigh...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Join a dynamic team to enhance Epic HB Claims applications, driving innovative solutions and optimizing workflows. Collaborate with stakeholders to ensure successful implementation and provide expert...

San Antonio, TXRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.