Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$80K - $95K *

Reimagine project delivery by overseeing capital initiatives, ensuring alignment with standards while managing budgets, schedules, and stakeholder communication for successful outcomes in healthcare c...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$134K - $230K *

Pioneer a transformative training and quality organization, leading a diverse team to enhance utilization management operations across a vast healthcare network, ensuring high standards and continuous...

Charlotte, NCRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $190K *

Elevate healthcare solutions by transforming complex data needs into scalable systems. Collaborate with cross-functional teams to design and build data pipelines and insightful dashboards that enhance...

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Reposted 1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$67K - $111K *

Deliver compassionate, expert behavioral health care throughout members' journeys, ensuring clinical excellence in a fast-paced, 24/7 environment as a trusted clinical partner in diverse cases and sup...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$134K - $249K *

Champion pharmacy excellence by leading strategic initiatives and operational oversight for a pharmacy benefit management program. Drive quality, compliance, and innovation while collaborating with cr...

Indiana, USRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Transform ERP management by leading governance and strategy for Oracle Cloud and UKG across health systems. Collaborate cross-functionally to enhance efficiencies and optimize processes, driving align...

Los Angeles, CARemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$123K - $205K *

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Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Join a dynamic team to oversee clinical research activities, ensuring compliance with regulatory standards and driving site performance. Collaborate with stakeholders to enhance patient safety and dat...

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5 days ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Engage with healthcare services and technology leaders to drive new business growth. Leverage a robust support system to build relationships, execute territory plans, and expand existing accounts whil...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$274K - $371K *

Elevate patient care through innovative clinical strategies in obesity and cardiometabolic development. Collaborate across teams to design and implement late-phase studies, ensuring alignment with glo...

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Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$272K - $340K *

Join a team that's driving CMC strategy and execution for innovative therapies. Lead cross-functional efforts in drug and device development, ensuring compliance and operational excellence from clinic...

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1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$280K - $305K *

Join a team that's redefining musculoskeletal (MSK) care by designing innovative, scalable solutions to improve patient outcomes and delivering high-quality, empathetic care to diverse populations wit...

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4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by leading pharmacy operations, enhancing client engagement, and driving continuous improvement initiatives. Oversee a team of clinical professionals to ensure high-quality pharmacy s...

Nashville, TNRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $200K *

Drive strategic medical initiatives in Rare Neurology, collaborating with cross-functional teams to enhance patient outcomes. Leverage your expertise to shape launch strategies and foster relationship...

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1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $195K *

Drive change management initiatives that enhance employee engagement and operational efficiency. Collaborate across teams to ensure successful adoption of technology and policy changes, while providin...

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2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$275K - $350K *

Lead the charge in transforming operations by integrating AI and technology to enhance member and clinician experiences, ensuring efficient care delivery and operational excellence across a distribute...

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3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that's defining and driving enterprise data governance for a federal agency. Collaborate with stakeholders to establish data quality frameworks and compliance protocols, ensuring best prac...

Washington, DCRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $160K *

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1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's redefining healthcare integration by leading innovative solutions in Epic BMDI. Leverage your expertise to enhance clinical workflows, ensure data integrity, and drive project succe...

Chicago, ILRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Unlock potential by leading integration efforts in healthcare technology. Collaborate with cross-functional teams to enhance clinical workflows and ensure seamless data exchange, while maintaining hig...

Chicago, ILRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$78K - $206K *

Unlock potential by leading clinical performance improvement projects for Medicare Provider Collaboration groups. Collaborate with teams to enhance population health outcomes, focusing on Stars qualit...

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1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$73K - $100K *

Transform website content management by executing timely updates across multiple product groups in AEM. Collaborate with teams to ensure accuracy and adherence to standards while enhancing user experi...

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3 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $112K *

Empower health transformation by leading a dynamic nursing team, driving operational excellence, and enhancing patient care through innovative practices and data-driven insights. Collaborate with inte...

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2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$114K - $187K *

Champion clinical laboratory operations by managing complex projects, ensuring timely study starts, and collaborating with cross-functional teams to deliver impactful results in precision medicine...

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2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join our team to drive sales across a defined portfolio, engaging healthcare organizations with our innovative solutions. Own the sales cycle from prospecting to closing while collaborating with inter...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.