Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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1
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$400K - $445K *

Join a team that's shaping the future of digital health by driving growth, expanding market access, and architecting commercial strategies that integrate innovative technologies for long-term success...

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Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$115K - $135K *

Transform clinical trial operations by leading a dynamic team to ensure seamless execution of device-based studies, from feasibility to close-out, while driving process improvements and fostering cros...

Boston, MARemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$99K - $182K *

Develop and lead a dynamic clinical support team, ensuring compliance with workflows and enhancing patient care through effective training, performance monitoring, and collaboration with nursing staff...

Fairhaven, MARemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$220K - $280K *

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Today

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$90K - $110K *

Engage with clients to showcase innovative healthcare solutions, driving sales success through impactful demonstrations and expert guidance. Collaborate with sales teams to address client needs and en...

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2 weeks ago

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$110K - $130K *

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Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $120K *

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Los Angeles, CARemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $130K *

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$96K - $144K *

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2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$248K - $461K *

Grow your career with us by providing strategic medical leadership for oncology agent development, coordinating clinical strategies, guiding trials, and collaborating with international experts to dri...

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Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$76K - $148K *

Play a key role in managing clinical trials, ensuring compliance and quality oversight of project deliverables while collaborating with cross-functional teams to meet timelines and budget goals...

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Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$81K - $129K *

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Wilmington, DERemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

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2 weeks ago

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$242K - $403K *

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1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$88K - $190K *

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2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$115K - $158K *

Elevate your career by driving strategic initiatives in Medicare and Medicaid. Collaborate with leaders to analyze challenges, develop insights, and implement solutions that foster sustainable growth...

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3 days ago

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$110K - $130K *

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2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

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Chicago, ILRemote

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$140K - $175K *

Drive operational excellence by leading strategic initiatives and managing a team to enhance Care Operations. Transform high-level strategies into scalable systems that improve care delivery and patie...

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2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$97K - $145K *

Join a team that's dedicated to ensuring accurate coding and compliance for clinical services, leveraging your expertise to enhance revenue cycle management and contribute to optimal healthcare outcom...

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Reposted 6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Collaborate in a high-growth, cross-functional role to transform ambiguous challenges into strategic outcomes, driving key initiatives that propel company growth and operational excellence...

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Reposted 1 month ago

  •   Less than 5 years exp.  •   Healthcare

$273K - $381K *

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5 days ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

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New York City, NYRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$83K - $112K *

Partner with us to navigate complex patient cases and ensure seamless access to care. Utilize critical thinking and communication skills to manage authorizations and appeals, collaborating with divers...

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Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

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RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.