Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
More
1
caret down

$151K - $261K *

Elevate NGS diagnostic innovation by leading algorithm development to enhance clinical outcomes. Drive analytical validation, regulatory readiness, and algorithm performance in oncology, focusing on s...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $230K *

Elevate drug substance development by leading process innovation and CDMO partnerships. Drive projects from early development through commercialization, ensuring regulatory compliance and strategic al...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$175K - $230K *

Lead the charge in shaping AI products for a resilient global supply chain. Drive strategies, governance, and scalable AI delivery while partnering across teams to enhance data readiness and operation...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Enterprise Technology

$175K - $230K *

Lead the strategy and implementation of AI-driven products leveraging large language models to enhance supply chain efficiency. Collaborate with cross-functional teams to ensure data readiness and dri...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Enterprise Technology

$125K - $224K *

Contribute to groundbreaking research by enhancing atmospheric radiative transfer models, collaborating with a team of experts, and driving innovation in numerical methods within the scientific commun...

US-AnywhereRemote

1 week ago

  •   15+ years exp.  •   Aerospace & Defense

$171K - $214K *

Join a pioneering oncology research team to lead translational projects, integrating cutting-edge single-cell and spatial biology technologies to enhance drug discovery and clinical applications acros...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Accelerate progress at the forefront of clinical research by designing and conducting studies that enhance our understanding of new therapies, while collaborating with multidisciplinary teams and appl...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $135K *

Advance your career by leading complex AI and IT projects. This high-visibility role entails managing cross-functional teams and driving accountability across multiple workstreams, ensuring successful...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$234K - $271K *

Lead the charge in developing cutting-edge AI and image processing solutions for cardiac imaging, translating clinical needs into innovative algorithms while collaborating across functions to enhance...

US-AnywhereRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $170K *

Accelerate progress at leading innovative projects while driving business growth and team success through strategic leadership, client engagement, and operational excellence in the biomanufacturing se...

US-AnywhereRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$165K - $206K *

Lead the charge in transforming complex data into actionable insights, partnering with stakeholders to measure and optimize commercial strategies, and architecting large datasets to influence critical...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$173K - $277K *

Innovate within the AI Center of Excellence to architect and govern advanced AI solutions, shaping how AI is designed, deployed, and scaled across all engineering projects with a commitment to excelle...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$152K - $190K *

Join a team that's shaping the future of healthcare through innovative software solutions. As a technical leader, you'll drive the design and development of next-gen clinical data platforms while ment...

US-AnywhereRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Lead impactful client engagements by managing complex drug substance and product development programs. Drive success through cross-functional teamwork, strategic oversight, and proactive client relati...

US-AnywhereRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Advance pharmaceutical marketing analytics by leading insight delivery and measurement strategies. Oversee KPI frameworks, reporting processes, and data visualization to ensure compelling insights tha...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Join a team that's leading innovative Cost Improvement Projects in medical devices. You'll manage engineering efforts, ensuring compliance while driving change and collaboration across cross-functiona...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Contribute to advanced data management in clinical trials, overseeing data integrity and quality through collaboration with teams and external vendors. Lead initiatives in database development and ris...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$122K *

Champion project success by leading the global team in Oncology, ensuring adherence to budgets, timelines, and quality standards while fostering client relationships and supporting business developmen...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$145K - $165K *

Lead the charge in scientific communications for mid to large accounts, ensuring compelling scientific narratives and strategic growth through effective project management and team collaboration, whil...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$118K - $197K *

Shape the future of animal health by leading regulatory strategies for innovative veterinary products. Collaborate globally, engage with regulatory agencies, and drive project success through expert n...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$152K - $180K *

Shape the future of genomics by leading statistical genetics analyses that drive insights, support research programs, and facilitate impactful collaborations across teams. Leverage cutting-edge method...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $180K *

Elevate your career by leading strategic marketing initiatives that drive growth, enhance client engagement, and foster collaboration across teams. leverage your expertise in a dynamic role that shape...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$121K - $164K *

Unlock your potential by leading the design of innovative solutions that integrate scientific informatics with lab automation, ensuring high-performance and scalable architectures across diverse envir...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Drive your career with impactful contributions in computer-aided drug design that integrates chemistry, AI, and machine learning within a dynamic, cross-disciplinary team focused on rapid molecule syn...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$115K *

Manage federal project implementation, ensuring success in costs, schedules, and quality. Lead a team while fostering strong client relationships and improving project processes to enhance customer ex...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.