Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.
Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.
High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.
Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.
Medical Strategy Associate Director
$191K - $238K *
Shape the future of oncology by leading medical strategy for prostate cancer projects. Collaborate with cross-functional teams to drive scientific communication and strategic initiatives, ensuring ali...
Yesterday
$80K - $85K *
Drive business performance through financial analysis and strategic insights. Collaborate with cross-functional teams to evaluate profitability, support budgeting, and identify opportunities for reven...
5 days ago
Director, Engineering (AI Patient Engagement Platform)
$180K - $230K *
Join a dynamic team as you lead engineering efforts to develop an AI Patient Engagement Agent, transforming clinical trials by automating patient interactions and enhancing operational efficiency for...
2 weeks ago
Medical Director -Pharmacy Appeals
$223K - $313K *
Shape the future of healthcare by leveraging your clinical expertise to review Medicare drug appeals, ensuring compliance and optimal value-based care through collaboration and analysis of complex cas...
6 days ago
$85K - $165K *
Champion safety in innovative nuclear fuel recycling by evaluating hazards, developing safety documents, and ensuring compliance with regulations. Collaborate in a dynamic team to enhance safety measu...
3 weeks ago
Account Specialist (Madison, WI)
$160K - $192K *
Join a dynamic team to drive commercial performance and enhance patient access through strong relationships with healthcare providers, executing strategic business plans in a pivotal role focused on i...
1 week ago
Regional Sales Director - Austin
$180K - $215K *
Drive regional success by leading launch execution and building high-performing teams. Foster customer relationships and ensure alignment with corporate goals in a fast-paced, entrepreneurial environm...
1 week ago
Applications Analyst- Epic Professional Billing
$67K - $111K *
Elevate your career by providing critical analysis and programming support for application software, ensuring a comprehensive and integrated information network that meets diverse customer needs and e...
2 days ago
$78K - $113K *
Innovate healthcare fraud prevention by leading complex investigations, evaluating medical necessity, and collaborating with regulatory agencies to ensure quality member care and safeguard plan assets...
Today
$78K - $113K *
Unlock potential by leading complex investigations into healthcare fraud, waste, and abuse. Collaborate with regulatory agencies and internal teams to ensure compliance and safeguard member care while...
Today
$110K - $165K *
Drive impactful clinical and technical research initiatives across global teams, ensuring project success from planning to execution. Collaborate with cross-functional partners to meet quality, budget...
Yesterday
Emergency Medicine - Physician -Grundy Center, IA
$210K - $250K *
Shape the future of rural healthcare by delivering comprehensive emergency care in a collaborative environment. Join a dedicated team at a critical access hospital, enhancing community health while en...
2 weeks ago
$201K - $251K *
Lead strategic forecasting initiatives to drive decision-making in oncology. Collaborate with cross-functional teams to develop long-term models and communicate insights that shape product and portfol...
2 weeks ago
Psychiatric Nurse Practitioner
$130K - $176K *
Join a team that fosters mental wellness by diagnosing and treating patients with diverse psychiatric conditions. As a key member, you'll develop tailored treatment plans and promote effective medicat...
1 month ago
Medical Monitor (US Board-Certified Gastroenterologist)
$210K - $250K *
Innovate with us to enhance patient safety in global clinical studies. As a key medical expert, you'll provide critical input, oversee trial safety, and collaborate with teams to ensure compliance and...
2 weeks ago
Clinical Consultant (Vue PACS)
$90K - $143K *
Unlock potential by serving as a clinical consultative partner, guiding healthcare customers through PACS solutions, ensuring successful implementation, and fostering strong relationships to drive cus...
Reposted yesterday
Senior Director, Head of Analytical Development
$250K - $275K *
Transform the future of drug development by leading Analytical Development for small molecules and oligonucleotides. Drive scientific strategy, build a high-performing team, and ensure regulatory read...
2 weeks ago
Associate General Counsel, Legal (US)
$200K - $398K *
Drive impactful legal strategies in a global clinical research environment, guiding senior leadership on complex regulatory and compliance matters while fostering innovation and risk management across...
3 weeks ago
$111K - $167K *
Join a team that's driving healthcare transformation by leading client integration initiatives. Collaborate across departments to ensure seamless transitions, operational readiness, and long-term succ...
Yesterday
Payer Engagement Lead - Regional Accounts
$214K - $234K *
Champion strategic payer engagement across regional markets, building relationships that enhance patient access to therapies. Connect national strategies with local execution for optimal outcomes in c...
Reposted 3 weeks ago
$160K - $190K *
Elevate healthcare solutions by transforming complex data needs into scalable systems. Collaborate with cross-functional teams to design and build data pipelines and insightful dashboards that enhance...
Reposted 2 weeks ago
Clinical Informatics & Ontology Lead
$120K - $145K *
Lead the design and governance of clinical ontologies and terminology services, ensuring data quality and alignment with product needs. Collaborate cross-functionally to enhance data normalization and...
Yesterday
VICE PRESIDENT, OPERATIONS (SOUTHEAST)
$180K - $220K *
Drive the future of healthcare operations by leading a $300M portfolio, fostering physician partnerships, and executing growth strategies while managing financial and operational performance for a dyn...
Reposted 1 week ago
Assistant Professor, Physician Assistant
$110K - $159K *
Join us to foster an innovative educational environment, providing leadership and mentorship while enhancing curriculum and teaching methodologies to ensure student success and engagement in learning...
3 weeks ago
Advanced-Practice Provider (FT/PT) | Emergency Medicine | Ames | PR2026-017
$90K - $110K *
Engage in dynamic emergency medicine as an Advanced-Practice Provider, collaborating with a dedicated team to enhance patient care and well-being in a supportive, multi-specialty clinic environment...
3 weeks ago
What types of $100,000+ jobs are available in Iowa?
Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.
Which Iowa cities have professional jobs paying $100,000 or more?
Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.
How can I find high-paying jobs in Iowa on Ladders?
Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.
Do Iowa job listings on Ladders include salary information?
Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.