Explore $100K+ Jobs in Alabama

Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.

Where to Find Professional Jobs in Alabama

Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.

Industries and Roles

High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.

Find the Right Alabama Opportunity

Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.

Advance Your Career in Alabama

Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.

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$260K - $270K *

Unlock your potential as a Psychiatrist, providing advanced outpatient care via virtual platforms. Collaborate with multidisciplinary teams to deliver comprehensive treatment for diverse psychiatric c...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Business Services

$90K - $110K *

Unlock potential by enhancing urology patient evaluations and care. This role focuses on outpatient assessments, patient follow-ups, and adherence to safety standards, ensuring high-quality service in...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Champion patient care by managing breast cancer follow-ups, collaborating on treatment plans, and ensuring confidentiality. Provide timely diagnostics and support for high-risk patients while maintain...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$268K - $466K *

Champion early clinical development in a dynamic team. Lead clinical research physician role for first-in-human studies, ensuring compliance and collaboration across scientific and regulatory areas to...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $135K *

Join a team that shapes innovative medical strategies, driving excellence in healthcare content. Collaborate with experts, cultivate client relationships, and inspire teams to elevate project outcomes...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$225K - $281K *

Join a team that's pushing the boundaries of oncology research! This key role involves designing and leading clinical trials, ensuring data integrity, and collaborating with global experts to advance...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$225K - $281K *

Explore your career in clinical development as you design and lead innovative oncology studies, ensuring data integrity and compliance while collaborating with cross-functional teams and cultivating r...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$89K - $133K *

Empower success by leading healthcare technology implementations, optimizing workflows, and ensuring compliance. Collaborate across teams to guarantee smooth integrations and enhance system functional...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$85K - $100K *

Lead the charge in providing primary care under physician supervision, collaborating on medical protocols, and enhancing clinic operations while mentoring learners in a supportive teaching environment...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$250K - $300K *

Join a team that's dedicated to transforming mental health care through comprehensive assessments and treatments. Collaborate with professionals to provide person-centered care and make a meaningful i...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Lead the charge in providing comprehensive medical care to diverse patients, collaborating with a skilled healthcare team while ensuring compliance with standards and promoting wellness in a supportiv...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$250K - $300K *

Join a team that's dedicated to transforming mental health care through compassionate treatment and collaboration. As a key provider, you'll assess, treat, and support patients while fostering a posit...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Transform the clinical sales landscape by leading a regional team to drive utilization growth, enhance patient treatment metrics, and foster cross-functional collaboration for commercial success in in...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$222K - $356K *

Unlock your potential as a Senior Safety Physician, leading safety oversight for late-stage CNS clinical development. Collaborate with cross-functional teams to drive risk management and regulatory su...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$291K *

Engage with a dynamic team as a CRNA in a floating role, providing regional anesthesia across multiple facilities. Enjoy autonomy, diverse cases, and a supportive environment with competitive compensa...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Optimize reimbursement strategies and regulatory compliance by leading analysis, developing policies, and mentoring teams. Drive operational excellence and foster relationships with stakeholders to en...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a collaborative team dedicated to advancing radiation oncology through innovative technology and expert care. Contribute to patient safety and treatment quality while enjoying a fulfilling career...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$245K - $265K *

Optimize partnerships with Medical Experts to enhance neurology care. Drive strategic insights and educational initiatives while collaborating across teams to influence business decisions and improve...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$129K - $231K *

Reimagine drug discovery as you lead molecular pharmacology efforts in neuroscience. Collaborate across teams to develop strategies, interpret data, and advance innovative therapies for sleep-wake dis...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Lead the charge in providing comprehensive medical care to diverse patient populations, ensuring accurate diagnoses, effective treatments, and patient education while collaborating with healthcare tea...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $155K *

Empower patients by delivering compassionate, patient-centered palliative care through virtual consultations. Collaborate with a dynamic team to enhance quality of life for members with complex needs...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$250K - $300K *

Join a dynamic oral surgery practice offering broad surgical care and advanced technology. Collaborate with a supportive team, access mentorship, and explore a clear path to partnership while serving...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $300K *

Join a team that's dedicated to enhancing patient care through expert evaluation and treatment. Collaborate with medical professionals to improve quality and cost-effectiveness while participating in...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$250K - $300K *

Partner with us to enhance patient care by evaluating and treating complex cases in Colon and Rectal Surgery. Engage in academic programs and improve care quality while managing inpatient and outpatie...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Shape the future of healthcare revenue management by leading IDR processes, ensuring compliance, and driving data-informed improvements while mentoring a team of analysts to optimize workflows and enh...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Alabama?question toggle

    Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.

  • Which Alabama cities have high-paying professional jobs?question toggle

    Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.

  • Are the Alabama jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.

  • How can I find a $100K+ job in Alabama?question toggle

    Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.

  • Do Alabama jobs listed on Ladders require in-person work?question toggle

    Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.