Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Senior Oncology Account Manager, Milwaukee
$150K - $230K *
Join a team that's dedicated to advancing oncology care by promoting innovative products and building strong relationships with healthcare professionals. Leverage your expertise to drive brand value a...
1 week ago
Regional Sales Director - New Orleans
$180K - $215K *
Lead regional launch initiatives, driving sales performance and team success through strategic execution and strong customer engagement in a fast-paced environment...
1 week ago
Clinical Informatics Integrator
$110K - $130K *
Lead the charge in managing informatics projects from planning to delivery, ensuring timely decision-making and risk management. Collaborate with cross-functional teams to enhance health information e...
4 weeks ago
$120K - $145K *
Join a team that's transforming medicine by engaging with KOLs and healthcare professionals. Leverage your clinical expertise to communicate product benefits, support education, and drive strategic in...
Reposted 5 days ago
Senior Director, Strategic Accounts
$140K - $190K *
Empower our sales team by driving strategic growth in key accounts. Leverage your expertise in Enterprise SaaS to navigate complex sales in the Life Sciences sector, fostering partnerships and deliver...
2 weeks ago
$97K - $104K *
Join a team that's dedicated to enhancing patient care through effective leadership and innovative program development in a dynamic rehabilitation environment. Oversee clinical operations, manage staf...
2 weeks ago
Director, Global Regulatory Affairs - Cardiometabolic Disorders
$195K - $264K *
Drive global regulatory strategies for obesity and cardiometabolic disorders, ensuring alignment across teams and leading interactions with health authorities. Leverage scientific expertise to navigat...
Today
Associate Director, Central Monitoring
$164K - $247K *
Join a dynamic team to lead central monitoring efforts in clinical trials, driving data-driven insights and risk management strategies. Collaborate across functions to enhance monitoring efficiency an...
4 weeks ago
$146K - $225K *
Manage compliance for the Affirm Card program, ensuring regulatory adherence across marketing, onboarding, and servicing. Collaborate with cross-functional teams to navigate complex compliance challen...
4 weeks ago
$75K - $90K *
Unlock new business opportunities by developing strategic marketing and sales plans. Collaborate with executives to secure and grow employer accounts, driving revenue growth and expanding market share...
2 days ago
Clinical Lead - Senior Site Activation Lead
$116K *
Drive impactful site activation strategies, collaborating with cross-functional teams to ensure timely delivery of clinical projects while enhancing communication and mitigating risks throughout the p...
1 week ago
Enterprise Account Executive - Healthcare
$240K - $330K *
Pioneer growth in the healthcare sector by driving new business and cultivating strong client relationships. Utilize expert sales skills to oversee complex deals from prospecting to closing in a consu...
Reposted today
Clinical Trial Manager II, Dermatology & Rheumatology CRO, USA
$100K - $120K *
Engage with a dynamic CRO to oversee clinical monitoring and enhance site performance. Foster relationships, ensure compliance with regulations, and lead a team in delivering quality outcomes in clini...
Reposted 3 weeks ago
Sr. Director, Integrated Evidence Generation Lead
$175K - $210K *
Lead pioneering evidence generation initiatives to inform oncology product strategies and lifecycle management through cross-functional collaboration and data-driven decision-making...
Reposted 2 days ago
Senior Medical Director - Oncology
$254K - $382K *
Transform clinical research by leading strategic medical initiatives, ensuring operational excellence, and fostering collaboration across teams. Drive innovation and mentor future leaders while delive...
2 days ago
Manager, AI & Workflow Operations - Licensed (RN, NP, PA, or MD, RPh, PharmD)
$100K - $120K *
Transform healthcare delivery by leading operations for a growing telehealth practice. Collaborate with clinical teams to enhance patient care through innovative solutions and efficient workflows, ens...
1 week ago
$378K - $420K *
Transform pharmacovigilance by leading a dedicated team, enhancing systems, and ensuring compliance across clinical and commercial products while driving safety strategy and governance...
4 weeks ago
$138K - $172K *
Empower revenue teams as a Senior Business Systems Analyst, driving efficiency through Salesforce architecture, process design, and actionable data across GTM, Marketing, Sales, and Customer Success o...
Reposted 1 week ago
Senior Medical Science Liaison, Neuroscience - New England Region
$151K - $237K *
Partner with us to advance medical strategy as a Medical Science Liaison, engaging with KOLs and HCPs, interpreting scientific data, and fostering expert networks to improve patient outcomes in a dyna...
2 weeks ago
Nurse Practitioner-Peds Hospitalists-FT-1st Shift
$95K - $115K *
Empower patients through comprehensive nursing care, diagnostics, treatment, and health education while collaborating on quality improvement and educational initiatives supporting pediatric health out...
Reposted 2 days ago
Regional Health Physicist - South Central US
$110K - $151K *
Champion operational excellence by ensuring radiation safety and EHS compliance across cyclotron manufacturing and PET nuclear pharmacy facilities in the South Central US, while collaborating with cro...
1 week ago
$100K - $120K *
Join a team that's driving talent acquisition for commercial roles, enabling product launches and market expansion. Collaborate with leaders to build pipelines and deliver high-quality candidates in t...
2 weeks ago
Analyst/Senior Analyst, Business Operations & Strategy
$95K - $130K *
Tackle strategic business challenges by leveraging data insights to drive growth. Collaborate cross-functionally to enhance operational efficiency, support marketing initiatives, and influence product...
Yesterday
$120K - $150K *
Accelerate progress at the forefront of newborn health by leading strategic initiatives, managing multi-country programs, and driving impactful interventions to reduce neonatal mortality and stillbirt...
1 week ago
Director Global Safety- Global Periodic Aggregate Safety Reports
$191K - $258K *
Shape the future of global safety by leading the development and submission of periodic aggregate safety reports. Drive compliance and collaboration across teams while managing a diverse global team t...
3 days ago
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.