Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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$120K - $170K *

Help us develop innovative thermal solutions for data centers by simulating system performance and guiding design. Collaborate with cross-functional teams to evaluate emerging technologies and enhance...

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$100K - $150K *

Join a team that's dedicated to enhancing clinical support through technical expertise and customer training. Drive product demonstrations and ensure customer satisfaction while collaborating with sal...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$120K - $145K *

Elevate security standards by leading bug bounty programs, conducting audits, and enhancing software supply chain security. Collaborate across teams to build innovative tools that protect users and en...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Drive impactful marketing strategies by transforming complex data into actionable insights, collaborating with senior stakeholders, and leading analytical projects from start to finish, all while fost...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate your career by building strategic partnerships in the AI ecosystem. Collaborate with customers to tackle complex AI training challenges and shape innovative solutions, driving growth for a pio...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Drive analytical excellence by auditing freight contracts and invoices, ensuring compliance and accuracy. Collaborate with teams to enhance audit processes and mentor junior analysts, contributing to...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Unlock your potential by providing advanced process engineering support for GMP manufacturing operations. Lead technical investigations, scale-up activities, and operational improvements while collabo...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$86K - $143K *

Unlock your potential by driving quantitative analyses and model development to enhance decision-making. Collaborate with stakeholders to refine models and deliver insightful analytics in a dynamic fi...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$161K - $190K *

Transform the digital commerce experience by owning a high-velocity experimentation roadmap. Collaborate across teams to enhance customer journeys, improve conversion rates, and establish a robust exp...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$69K - $99K *

Lead the charge in engineering design for electric utility distribution projects, overseeing construction sketches, cost estimates, and project scoping while collaborating with teams to ensure complia...

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$100K - $110K *

Drive innovation by performing advanced pipe stress analysis using various software tools. Collaborate with teams to ensure compliance with engineering standards while enhancing processes and resolvin...

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$100K - $110K *

Engineer innovative piping solutions by performing pipe stress analysis using advanced software. Collaborate with teams to ensure compliance with engineering standards while enhancing processes and ma...

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$130K - $160K *

Advance AI engineering by designing LLM-powered systems and optimizing data retrieval architectures. Collaborate with cross-functional teams to enhance CoreStory's narrative intelligence platform with...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$116K - $229K *

Drive innovative supply chain solutions by leveraging data science to optimize processes, enhance decision-making, and deliver impactful analytical models that transform client operations and improve...

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$116K - $229K *

Innovate analytical solutions to optimize supply chains, leveraging data science and modeling techniques. Collaborate with stakeholders to enhance decision-making and drive efficiency across operation...

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$108K - $125K *

Champion innovative solutions as a Full Stack Engineer, delivering impactful features and enhancing systems across projects. Collaborate, design, and optimize applications with a focus on performance...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Elevate our search capabilities by architecting high-scale solutions, leading multi-quarter transformations, and ensuring operational excellence across a global cloud infrastructure while mentoring em...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$145K - $185K *

Join a team that's driving marketing excellence by owning and scaling our marketing operations. You'll lead cross-functional projects, optimize tech stacks, and ensure data integrity to enhance pipeli...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $115K *

Lead the charge in transforming complex business needs into impactful analytic products. Collaborate with stakeholders to design, develop, and maintain reusable semantic models that enhance decision-m...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$200K - $215K *

Drive the design and deployment of innovative data and AI solutions, leveraging expertise in LLMs, agentic AI, and cloud technologies to enhance business value and ensure compliance with industry stan...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Champion exceptional research outcomes by guiding clients through complex projects. Leverage your expertise in methodology and analysis to deliver actionable insights, while collaborating with cross-f...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Lead solar resource assessments and performance analytics for utility-scale projects. Engage with clients, optimize energy yield, and enhance methodologies while ensuring operational excellence in sol...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$82K - $128K *

Shape data-driven strategies by developing and automating analytics solutions. Collaborate with cross-functional teams to enhance reporting capabilities and optimize operational performance in a dynam...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $210K *

Join a dynamic team to lead AI platform strategy and operations, ensuring seamless access and governance while driving enterprise-wide adoption and continuous improvement of innovative AI solutions...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$137K - $235K *

Empower patients by leading safety assessments and analyses for innovative products. Collaborate with cross-functional teams to ensure regulatory compliance and drive safety strategies, while mentorin...

Reposted 5 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.