Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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$81K - $102K *

Unlock potential by analyzing market insights and coordinating engagements with external partners to inform policy decisions and enhance community relations across the district. Drive strategic initia...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$119K - $180K *

Lead the development of innovative web platforms, collaborating with cross-functional teams to enhance content management systems. Drive technical decisions and foster a culture of growth while ensuri...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$155K - $220K *

Drive innovation in actuarial functions by leveraging AI and advanced analytics. Lead high-impact initiatives that transform insights into actionable business strategies, enhancing decision-making and...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$77K - $108K *

Innovate high-performance AI network fabrics for accelerated computing. Engage with clients to deliver tailored solutions, ensuring optimal configurations for GPU clusters and data-center infrastructu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$202K - $289K *

Champion growth in environmental services by leading business development, managing complex projects, and fostering client relationships in the power industry. Leverage your expertise to navigate regu...

United StatesRemote

2 weeks ago

  •   15+ years exp.  •   Technical Services

$110K - $130K *

Lead the charge in transforming product vision into market success by leveraging customer insights, strategic positioning, and cross-functional collaboration to drive impactful go-to-market strategies...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $105K *

Transform global operations by supporting Power Automate workflows, enhancing collaboration with regional teams, and driving continuous improvement in automation processes to optimize efficiency and e...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Unlock potential by developing real-time automation solutions across manufacturing and enterprise levels. Collaborate with a dynamic team to enhance operational efficiency and mentor peers while tackl...

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Transform the future of automation solutions by engineering real-time controls and information systems across manufacturing environments. Collaborate with a dynamic team to enhance operational efficie...

Philadelphia, PARemote

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$250K - $275K *

Transform the future of drug development by leading Analytical Development for small molecules and oligonucleotides. Drive scientific strategy, build a high-performing team, and ensure regulatory read...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Deliver impactful AI strategies while leading diverse teams and collaborating with executives. Drive client growth and innovation by leveraging your expertise in life sciences and technology transform...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Business Services

$85K - $100K *

Champion compliance excellence by reviewing retail communications to ensure adherence to regulations and firm policies. Collaborate with teams to maintain high standards and support organizational goa...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Champion new business growth by leveraging your consultative sales expertise to build relationships with utility and public sector clients, driving revenue and delivering tailored solutions that meet...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $120K *

Empower Public Safety agencies by driving sales and fostering relationships across a multi-state territory. Manage the sales cycle through consultative partnerships, ensuring pipeline growth and reven...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$75K - $158K *

Champion operational excellence by managing the Avantra platform for SAP, ensuring secure, efficient monitoring and automation across diverse environments while collaborating with cross-functional tea...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$165K - $215K *

Engage with innovative AI/ML teams to drive customer success in leveraging AI. You'll cultivate client relationships, manage adoption, and ensure measurable impacts through tailored solutions and stra...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Join a team that's shaping commercial strategy by transforming complex data into actionable insights. Collaborate with cross-functional leaders to identify growth opportunities and drive strategic ini...

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $120K *

Shape the future of social and behavioral research by leveraging advanced statistical methods and collaborating with multidisciplinary teams to analyze complex data and support impactful NIH-funded pr...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Advance healthcare solutions by building executive relationships and driving enterprise sales. Lead the sales lifecycle, develop strategic accounts, and leverage modern tools to optimize revenue growt...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$105K - $130K *

Lead the charge in executing automation projects across North America, focusing on facility layout and equipment installation while ensuring safety and operational excellence through collaboration and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Food & Beverages

$90K - $110K *

Grow your career with a dynamic team focused on generating new business in the public sector. Utilize a consultative sales approach to build relationships and deliver tailored solutions, driving reven...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$150K - $160K *

Champion cloud and application security by enhancing AWS practices, collaborating with cross-functional teams, and driving continuous improvement to ensure secure and compliant environments...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Partner with us to enhance clinical IT solutions as an Epic Analyst II, providing critical support, training, and implementation for Epic EHR systems. Collaborate with teams to optimize workflows and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Elevate manufacturing processes by optimizing operations, conducting trials, and leading engineering initiatives. Collaborate across teams to enhance safety, quality, and efficiency while driving cont...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$150K - $180K *

Optimize clinical program analytics by leveraging pharmacy expertise to enhance data integrity, design evaluation frameworks, and ensure compliance with healthcare standards, while mentoring analysts...

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.