Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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$151K - $241K *

Develop and optimize AI solutions for enhanced member experiences, integrating cutting-edge technologies and engineering practices. Collaborate with cross-functional teams to ensure reliable, scalable...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$194K - $259K *

Innovate data solutions by building robust models and pipelines, translating business needs into technical specifications, and mentoring junior engineers to enhance data engineering practices and code...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Manage compliance and lifecycle support for GxP laboratory equipment, ensuring validation and maintenance. Collaborate with teams to enhance operational efficiency and promote continuous improvement i...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $90K *

Advance quality assurance initiatives and optimize workflows in a remote healthcare contact center. Collaborate cross-functionally to enhance compliance, improve patient outcomes, and drive continuous...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$171K - $269K *

Lead the charge in defining and evolving data architecture and engineering standards for scalable, secure enterprise data platforms. Collaborate across teams to deliver reliable, actionable data produ...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Join a team that's redefining enterprise data management by leading cross-functional initiatives, ensuring data reliability, and driving strategic insights through advanced program management and tech...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $155K *

Unlock potential by designing and deploying enterprise-scale AI applications that enhance business processes through Generative and Agentic AI solutions. Collaborate with cross-functional teams to ope...

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $145K *

Join a dynamic team to design, develop, and maintain full-stack applications, leveraging Python, AWS, and Terraform. Lead projects from ideation to deployment while mentoring junior engineers and ensu...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Join a dynamic team to enhance application security across web apps, APIs, and cloud services. Collaborate with development squads to prioritize vulnerabilities and implement proactive remediation str...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Transform application security practices by enhancing web, API, and cloud service protections. Collaborate with development teams to remediate vulnerabilities and integrate security into CI/CD workflo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$115K - $165K *

Lead the charge in shaping software product strategy and lifecycle for analytics solutions. Collaborate across teams to enhance user experience and drive measurable outcomes, ensuring alignment with c...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Champion the management and execution of complex e-discovery projects, collaborating with legal teams to ensure successful outcomes. Oversee multiple projects while mentoring a team, maintaining quali...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$108K - $130K *

Innovate within the IT FinSight Delivery team by designing, developing, and testing software systems. Collaborate with stakeholders to solve complex business challenges and enhance data integration so...

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $135K *

Join a team that's driving strategic change by managing multiple customer programs. This role requires strong project governance, risk management, and the ability to coach junior team members in a dyn...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$115K - $145K *

Transform business operations by developing and deploying AI solutions that enhance product capabilities and customer experiences. Collaborate with cross-functional teams to integrate machine learning...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$70K - $115K *

Drive impactful data-driven decisions by transforming insights into actionable strategies. Collaborate with leadership to enhance warehouse operations through advanced analytics, reporting tools, and...

1 week ago

  •   Less than 5 years exp.  •   Transportation

$149K - $248K *

Shape the future of Navy readiness by leading advanced analytics and AI initiatives. Drive predictive modeling and machine learning solutions to optimize supply chains and enhance operational readines...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Engineer seamless integrations and automation across systems, enhancing operational efficiency and collaboration. Leverage your expertise in SaaS platforms and APIs to drive innovative solutions in a...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Transform the commercial landscape by building a scalable sales engine, driving strategic deals, and leading with innovation in a dynamic life sciences environment. Collaborate closely with leadership...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$87K - $195K *

Innovate with us to shape the future of AI-driven consulting. As a Senior Full-Stack Engineer, you'll collaborate closely with a dynamic team, owning key platform elements while delivering impactful f...

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$188K - $235K *

Grow your career with a hands-on leadership role in GTM analytics, driving data-driven decisions across Sales, Marketing, and Customer Success. Shape analytics products and insights to enhance pipelin...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$69K - $107K *

Champion client success by leveraging technical expertise to enhance platform value, optimize workflows, and drive measurable outcomes. Collaborate with cross-functional teams to deliver innovative so...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$166K - $279K *

Collaborate with cross-functional teams to drive technical success in prioritized opportunities, leveraging deep expertise in a specific product group to influence customer decisions and enhance Solut...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Lead the charge in transforming data accessibility for product teams and AI agents. Oversee a team of data engineers to build a robust platform that ensures secure, reliable data usage across the orga...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$91K - $202K *

Develop and validate quantitative models to enhance decision-making processes. Collaborate with stakeholders to assess model risks and ensure compliance through rigorous independent reviews and clear...

1 month ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.