Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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$100K - $300K *

The Research Engineer at Skild AI will develop scalable robotic systems to achieve general-purpose robotic intelligence. This role involves implementing state-of-the-art machine learning and robotics...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$215K - $315K *

Lead the charge in building secure, compliant infrastructure for our DaaS platform. Drive engineering excellence while collaborating with cross-functional teams to meet the needs of regulated customer...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$166K - $298K *

Pioneer innovative ML models for our small business lending program, transforming complex data into actionable insights. Collaborate with Credit and Product teams to enhance underwriting processes and...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Innovate at the intersection of healthcare and technology. In this role, engineer ML pipelines, enhance data reliability, and ensure production stability for healthcare information systems, impacting...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Empower data-driven decisions by designing and implementing scalable data pipelines using AWS services and Apache Spark, ensuring data quality and integration across diverse sources for analytics and...

2 days ago

  •   Less than 5 years exp.  •   Staffing

$140K - $170K *

Lead the charge in integrating AI capabilities across enterprise platforms, enhancing digital services for Veterans. Collaborate with teams to implement innovative solutions while ensuring security an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$134K - $168K *

Join a team that's transforming operational data into reliable customer experiences. As a Senior Machine Learning Engineer, you'll lead the development of innovative machine learning solutions, enhanc...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$70K - $118K *

Join a dynamic team to deliver impactful data analysis and reporting solutions, enhancing operational efficiency and decision-making through the Microsoft Power Platform and hands-on analytical suppor...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$320K - $405K *

Design and oversee the electrical architecture for cutting-edge data centers, ensuring robust power distribution and integration of advanced technologies. Collaborate with partners to enhance prefabri...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $150K *

Drive customer success by leading enterprise engagements and deploying AI solutions. Collaborate with cross-functional teams to ensure operational impact and long-term partnerships, enhancing efficien...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$175K - $210K *

Join us to lead the development of cutting-edge Operational AI solutions, collaborating with Global 2000 engineering teams. Drive technical integrity from architecture to production, ensuring impactfu...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Empower clients by designing and delivering scalable data solutions using Databricks. Collaborate with stakeholders to optimize data pipelines and enhance analytics capabilities, ensuring effective da...

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$83K - $103K *

Unlock potential by leading trade compliance initiatives, mentoring junior analysts, and collaborating across global teams to enhance import/export processes and ensure adherence to U.S. Customs regul...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$136K - $160K *

Elevate operations through AI-driven automation to enhance incident management, streamline ticket resolution, and optimize service health with self-healing observability, all while collaborating acros...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$139K - $151K *

Lead Finance analytics engineering and automation, transforming requirements into scalable data solutions. Collaborate with cross-functional teams to enhance data usability, reliability, and decision...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$180K - $240K *

The Technical Strategy & Execution Lead will oversee the execution of client, research, and product initiatives, transforming abstract ideas into actionable roadmaps. This role requires leading high-s...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Information Technology

$118K - $219K *

Shape the future of healthcare analytics by leading product strategy and execution. Collaborate with cross-functional teams to deliver impactful insights that empower clinicians and drive operational...

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$150K - $180K *

Innovate cutting-edge AI financial solutions by architecting and deploying advanced chat interfaces and reporting systems. Collaborate with elite engineers to enhance investment workflows for global c...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$127K - $159K *

Lead a dynamic Data Engineering team to develop innovative data solutions, supporting essential healthcare operations. Drive operational effectiveness, compliance, and collaboration while enhancing da...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Explore innovative AI solutions to enhance scientific workflows in Therapeutics Development. Collaborate across teams to design, implement, and evaluate AI-driven applications that support regulatory...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive impactful data strategies and analytics by leading a high-performing team, optimizing decision-making, and enhancing operational efficiency across the organization. Collaborate with stakeholders...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$160K - $200K *

Lead the technical direction for AI agent quality, defining metrics and evaluation systems. Collaborate with cross-functional teams to enhance agent performance and ensure quality in production enviro...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Empower decision-making by utilizing data-driven insights to enhance operations, supporting growth through statistical modeling and AI techniques while maintaining compliance in a complex regulatory e...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $155K *

Lead and mentor a team of data engineers to design, develop, and maintain scalable data pipelines and warehouses, collaborating with stakeholders to deliver key metrics and establish data strategy acr...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Transportation

$150K - $180K *

Help us drive the future of automation by owning AI agents that onboard applications and ensure self-healing workflows. You'll enhance existing systems, prioritize security, and collaborate across tea...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.