Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Manager, AWS Full Stack AI Engineering
$124K - $280K *
Drive innovation by leading multidisciplinary teams in AWS Full Stack AI Engineering, shaping cloud-native solutions, and guiding strategic client conversations throughout the software development lif...
2 weeks ago
Senior Manager, AWS Full Stack AI Engineering
$124K - $280K *
Transform multidisciplinary teams by leading AWS full stack AI engineering projects, guiding technical delivery, and shaping cloud-native solutions to meet client needs across the software development...
2 weeks ago
$160K - $185K *
Join a team that's transforming customer experiences through innovative technical solutions. As a Solutions Architect, you'll bridge business needs with technology, guiding clients from discovery to d...
6 days ago
$110K - $130K *
Empower our revenue team by building and scaling GTM systems. Collaborate with sales, finance, and engineering to enhance Salesforce and optimize workflows, ensuring accurate forecasting and seamless...
3 days ago
$180K - $230K *
Transform the future of platform strategy by leading Dynata+ to drive growth, enhance customer success, and establish a robust ecosystem. Oversee product development, P&L management, and enterprise-wi...
4 days ago
Enterprise Account Executive, East
$250K - $300K *
Execute innovative strategies to acquire and expand client relationships, leveraging expertise in AI/ML solutions. Be a proactive networker, navigating complex sales cycles to foster business growth a...
Reposted 4 days ago
$156K - $241K *
Oversee the management of demo environments, ensuring seamless integration and maintenance across departments. Collaborate with teams to deliver scalable technical architectures and optimize enterpris...
2 weeks ago
$100K - $130K *
Drive the future of revenue accounting by ensuring accurate recognition and compliance with ASC 606. Collaborate cross-functionally to streamline processes, support complex deals, and maintain audit r...
1 week ago
Advertising Campaign Strategist
$80K - $95K *
Join a team that's dedicated to maximizing advertising impact for clients. As a strategic advisor, you'll manage campaigns, analyze performance, and collaborate cross-functionally to drive success and...
3 weeks ago
Director of SEC Reporting and Technical Accounting
$170K - $210K *
Shape the future of financial reporting by leading SEC compliance and technical accounting. Drive policy development, optimize processes, and collaborate with cross-functional teams to support growth...
1 week ago
$125K - $150K *
Champion integrated demand generation to create a predictable pipeline from key accounts. Collaborate with marketing and sales teams to architect campaigns, optimize media strategies, and measure perf...
2 weeks ago
Sr Advisor Recruiting Specialist
$100K - $120K *
Shape the future of talent acquisition by driving full life cycle recruitment for financial advisors. Collaborate with leadership and engage candidates to build a diverse talent pipeline while trackin...
2 weeks ago
$80K - $95K *
Help us drive client success by managing campaigns and relationships. You'll oversee a portfolio, lead strategy discussions, optimize Meta campaigns, and ensure client satisfaction through proactive c...
6 days ago
$110K - $130K *
Unlock new business opportunities and expand existing client relationships by leveraging your expertise in enterprise sales. Collaborate with teams to deliver tailored solutions and drive growth in a...
2 weeks ago
$150K - $180K *
Lead and grow a high-performing Guidewire practice, driving strategy and delivery excellence in digital transformations for insurance clients, while fostering client relationships and mentoring teams...
Reposted 2 days ago
Technology Support Analyst – End User Training
$83K - $109K *
Shape the future of employee technology adoption by enhancing training and support programs. Collaborate with cross-functional teams to empower users, improve productivity, and foster a culture of con...
2 days ago
Staff Software Engineer, Cloud Infrastructure
$212K - $265K *
Elevate your career by developing cutting-edge cloud infrastructure that powers seamless operations across teams. Collaborate with talented engineers to enhance reliability, scalability, and efficienc...
Reposted 2 weeks ago
Software Engineer - CeFi Integrations Team
$95K - $115K *
Accelerate development in a fast-paced environment by enhancing and building integrations on the CoinLedger platform, collaborating with a dedicated team to improve user experience and operational eff...
Reposted 3 weeks ago
$101K - $150K *
Analyze complex data sets to drive insights and recommendations, collaborating with technical teams to enhance analytical capabilities and support client objectives through innovative visualizations a...
Today
Senior Systems Simulation Engineer
$120K - $145K *
Join a team that's shaping the future of embedded systems and simulation technologies. Collaborate globally to tackle complex technical challenges, enhance product reliability, and support innovative...
Today
$135K - $160K *
Champion innovative solutions by advising top financial institutions on identity verification and fraud prevention. Collaborate cross-functionally to ensure seamless client experiences and drive produ...
2 weeks ago
Manager - Software Development Engineering S 4D
$80K - $100K *
Unlock potential by leading a dynamic team of developers to deliver high-quality software solutions, collaborating with stakeholders, and driving strategic project initiatives while fostering a cultur...
2 weeks ago
Platform Product Manager - Healthcare SaaS
$110K - $130K *
Empower cross-functional teams to innovate and enhance platform capabilities, ensuring alignment with client needs and regulatory standards. Drive product vision from inception to adoption, leveraging...
1 week ago
$105K - $130K *
Join a dynamic team to lead multiple client engagements, driving innovative solutions and strategic direction. Foster cross-functional collaboration in a fast-paced environment with a focus on deliver...
Reposted 2 weeks ago
Engagement Manager - LE Diversified Industries
$116K - $207K *
Lead and manage mid to large Workday deployments, resolving complex issues while enhancing methodologies. Guide teams, ensure project success, and support executive expectations through effective comm...
4 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.