Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$131K - $205K *
Engage in the design and evaluation of electric power generation projects. Provide technical support and owner’s engineering services, focusing on thermal power systems. Collaborate on project develop...
3 weeks ago
AI Platform Analyst (St. Louis)
$71K - $106K *
Join a dynamic team as you support AI platform operations, ensuring quality and performance across custom applications. Collaborate with stakeholders to enhance user experience and drive continuous im...
Reposted 1 week ago
Senior Tooling and Automation Engineer
$120K - $160K *
Empower our Managed Services tooling ecosystem by designing integrations and automations. You'll lead the configuration of Jira Service Management, optimize alerting, and ensure seamless connectivity...
1 week ago
$95K - $105K *
Unlock potential by providing financial analysis and operational support for a complex government contract. Collaborate with leadership and teams to ensure effective budgeting, reporting, and subcontr...
Yesterday
$74K - $102K *
Explore and enhance HR systems by supporting configuration, maintenance, and improvements. Collaborate with stakeholders to resolve issues and drive system enhancements in a dynamic environment focuse...
4 weeks ago
$67K - $99K *
Develop and manage payroll processes, ensuring compliance and accuracy in timekeeping and payroll operations. Collaborate with HR and internal partners to enhance reporting systems and support employe...
Today
$61K - $98K *
Transform the landscape of risk management by overseeing collections and funding returns, analyzing transaction patterns, and collaborating with teams to resolve complex cases while driving process im...
2 weeks ago
$102K - $138K *
Lead the charge in delivering actionable insights through advanced analytics, supporting employer group partners with healthcare claims and utilization data. Collaborate across teams to enhance report...
2 weeks ago
$110K - $130K *
Drive operational excellence by enhancing reliability and performance of a SaaS platform. Collaborate with development teams to implement automation, incident management, and observability practices...
3 weeks ago
Account Executive, Government & Public Sector
$105K - $140K *
Transform your career by leading government sales efforts in a high-growth environment. Leverage your expertise to build relationships, create pipelines, and drive revenue for a cutting-edge product i...
2 weeks ago
Community Engagement Manager, Data Centers (Montana & Utah)
$265K - $295K *
Engage communities as a trusted partner, fostering relationships and collaboration throughout the lifecycle of infrastructure projects. Shape local engagement strategies, ensuring transparency and mut...
2 weeks ago
$75K - $90K *
Elevate your career by driving B2B demand generation through new client acquisition and account growth. Build strong relationships with key stakeholders while leveraging AI to enhance your sales strat...
3 weeks ago
Senior Enterprise Sales Director
$110K - $120K *
Drive revenue growth by leading high-performing sales teams and executing strategic sales initiatives. This role combines leadership with deep expertise in performance marketing to achieve ambitious b...
1 week ago
Director, Integrated Marketing
$130K - $160K *
Join a dynamic team to drive integrated marketing strategies that enhance brand visibility and support business growth through innovative campaigns, digital activation, and thought leadership across m...
2 weeks ago
IT Administrator, Business Applications
$115K - $151K *
Administer and enhance collaboration platforms, ensuring seamless integration and automation across teams. Collaborate with cross-functional departments to optimize workflows and improve operational e...
1 week ago
$126K - $137K *
Drive the evolution of a critical Vehicle Integration System, leveraging cloud software and embedded systems. Collaborate with cross-functional teams to enhance vehicle capabilities, ensuring seamless...
2 weeks ago
Associate Director, Paid Social
$96K - $135K *
Elevate your career as a strategic leader in paid social, driving growth through innovative strategies and high-performing teams. Leverage your expertise to optimize complex campaigns and foster colla...
1 week ago
$110K - $140K *
Unlock potential by owning executive-level client relationships, driving integrated strategies, and leading action-oriented touchpoints that translate insights into measurable outcomes while championi...
Reposted 4 weeks ago
$80K - $110K *
Transform your career by developing innovative software solutions in a collaborative Agile environment. Engage in all phases of the software development lifecycle while enhancing cybersecurity and ide...
Reposted 5 days ago
Senior Manager, Data Engineering
$146K - $229K *
Unlock potential by leading a high-accountability engineering team to architect and deliver innovative data products, enabling analytics and AI while fostering a culture of quality and collaboration a...
Today
Data & AI Technology Sales Director
$136K - $237K *
Accelerate growth by driving new sales opportunities in complex environments. Leverage deep expertise in data solutions and cloud technologies to build relationships with key clients and lead strategi...
3 weeks ago
Senior Product Manager, Integrations & Platform
$175K - $190K *
Innovate the deployment process by leading two squads to ensure seamless integration and self-service capabilities for customers, driving measurable outcomes and enhancing product effectiveness in a d...
2 weeks ago
$85K - $125K *
Unlock your potential as an AI-first Software Engineer, driving innovation in mobile marketplace experiences. Collaborate with cross-functional teams to enhance product quality and efficiency while le...
3 weeks ago
Privacy, Risk, and AI Consultant
$105K - $148K *
Lead assessments and develop strategies for cybersecurity, privacy, and AI risk. Collaborate with clients to enhance their security programs, ensuring compliance with regulations and frameworks while...
Today
Enterprise Architect - Automation & Integration Platforms
$150K - $170K *
Lead the charge in defining and overseeing enterprise automation architecture, ensuring scalable, secure solutions across platforms like ServiceNow and Microsoft. Collaborate cross-functionally to ali...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.