Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$156K - $220K *
Unlock your potential by leading the paid media strategy in a transformative role involving creative innovation and team development, driving growth through data-driven decisions across multiple chann...
Reposted 4 days ago
Integration Engineer- Boomi Platform
$100K - $140K *
Empower integration solutions by designing and maintaining critical connections across platforms, enhancing Quote-to-Cash processes and ensuring seamless data flow for thousands of merchants through i...
Yesterday
$199K - $230K *
Drive innovation by deploying and optimizing cloud infrastructure across federal environments. Leverage your expertise in AWS, Kubernetes, and automation tools to enhance platform scalability and secu...
1 week ago
$80K - $100K *
Optimize data-driven strategies to enhance customer engagement and retention. Collaborate with operations to implement scalable solutions in a dynamic startup environment, making a significant impact...
6 days ago
Senior IT Engineer, Automation
$142K - $161K *
Unlock potential by automating IT processes and workflows. In this senior role, you'll own and enhance automation systems, ensuring reliability and efficiency while collaborating with cross-functional...
4 days ago
Scientist II - Analytical Chemist
$80K - $95K *
Join a dynamic team to advance analytical chemistry methods and lead projects. Utilize your expertise in LC-MS for bioanalytical applications while mentoring junior scientists and driving innovation i...
4 days ago
Associate Demand Generation Manager
$110K - $130K *
Elevate our demand generation efforts by orchestrating targeted marketing strategies that engage key accounts in the Corporate Tech sector. Collaborate with leadership to drive pipeline growth and enh...
1 week ago
Sr Director, Analyst - Data Management and AI Readiness
$172K - $202K *
Lead the charge in delivering innovative insights and strategies for clients, leveraging in-depth market analysis and research expertise to address complex challenges and drive actionable results for...
Reposted 5 days ago
Project Manager (Data Projects)
$120K - $125K *
Transform data analytics initiatives by leading multiple projects, engaging stakeholders, and driving solutions from inception to delivery. Collaborate with technical teams to ensure alignment with mi...
1 week ago
$126K - $213K *
Engage with us to design, build, and maintain cutting-edge cloud infrastructure. You'll enhance our Kubernetes platform, drive GitOps practices, and empower developers through automation and infrastru...
Reposted 2 weeks ago
Director, Client Media Solutions
$100K - $140K *
Drive innovative media strategies for healthcare clients, leveraging audience insights and performance data. Collaborate with cross-functional teams to enhance planning processes and deliver impactful...
1 week ago
Software Engineering - Data Engineer (Python & Cloud Databases)
$84K - $132K *
Join a dynamic team to design and optimize high-performance databases, build Python ETL pipelines, and support AI initiatives, ensuring data integrity and efficiency for consumer-facing applications...
5 days ago
Lead Solutions Engineer, Strategic
$140K - $170K *
Shape the future of healthcare technology by leveraging your expertise to drive sales success. Collaborate with cross-functional teams to deliver tailored solutions, engage customers, and enhance prod...
2 weeks ago
$82K - $172K *
Design and implement innovative AI solutions, guiding pilot programs from conception to execution while collaborating across teams to enhance system capabilities and performance in a dynamic environme...
Reposted 2 weeks ago
$95K - $115K *
Transform traffic management by optimizing signal systems for efficient movement of people and goods. Collaborate with cross-functional teams to enhance product deployment and support, ensuring safety...
1 week ago
Business Analyst - MDM & Data Governance
$95K - $115K *
Unlock potential by bridging business and technical teams to define and implement master data management and governance solutions, ensuring data quality and compliance across the organization...
4 weeks ago
$140K - $160K *
Transform AI analytics by executing measurement frameworks and optimizing performance across voice and chat channels. Collaborate with cross-functional teams to deliver actionable insights and enhance...
3 weeks ago
$125K - $175K *
Elevate your career by leading innovative solar and energy storage projects. Drive technical excellence, mentor teams, and collaborate with stakeholders to shape sustainable energy solutions across No...
3 weeks ago
$80K - $95K *
Unlock potential by leading the design and optimization of enterprise workflows. Collaborate with cross-functional teams to enhance operational efficiency and drive data-driven decisions within a dyna...
3 weeks ago
Senior Data Engineer - Data Platform
$130K - $160K *
Champion the migration to a modern Databricks lakehouse, designing robust data pipelines and ensuring data quality. Collaborate with teams to enhance analytics capabilities and set technical standards...
2 weeks ago
$98K - $206K *
Unlock the potential of data engineering by automating cloud data ingestion and transformation processes. Utilize cutting-edge AWS services to ensure reliability and performance in a mission-driven en...
Reposted 2 weeks ago
$160K - $200K *
Drive innovation by designing and developing scalable backend services, collaborating closely with engineering teams to enhance platform performance and reliability while mentoring junior developers a...
3 weeks ago
Internal Audit - Technology Audit & Analytics Advisor - Hybrid
$102K - $170K *
Join a team that's transforming Internal Audit through data analytics and technology. Contribute to innovative audit techniques while collaborating with stakeholders to enhance audit effectiveness and...
Today
Spotfire Sales Executive - Energy
$110K - $130K *
Drive growth by managing end-to-end sales cycles in the Energy sector, enhancing customer relationships, and executing strategies to exceed targets while collaborating with cross-functional teams for...
5 days ago
Compliance Services Consultant
$110K - $130K *
Unlock potential by managing senior-level client relationships and navigating complex regulatory matters. Collaborate with compliance experts to deliver actionable solutions that enhance client operat...
2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.