Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$100K - $160K *

Join a team that's transforming healthcare with AI solutions. As an AI Solutions Engineer, you'll develop integrations and tools that enhance customer workflows, bridging the gap between clients and o...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Unlock potential by designing and building robust data pipelines for healthcare transactions. Collaborate with partners to ensure seamless integration and reliability of data systems, enhancing operat...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform data into actionable insights by mastering analytics across diverse domains. Collaborate with cross-functional teams to optimize reporting workflows and drive impactful solutions in a fast-p...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$175K - $185K *

Join a team that's redefining finance analytics by leading strategic forecasting and performance management. Drive impactful financial insights and methodologies while collaborating with leadership to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $125K *

Unlock potential by leveraging advanced analytics and consultative skills to drive client success in the Consumer Healthcare vitamins sector. Collaborate cross-functionally to deliver insights and fos...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Inspire data-driven decision-making as you lead analytics and predictive modeling efforts. Collaborate across teams to enhance patient engagement, forecast demand, and measure impact, driving strategi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in transforming complex revenue-cycle challenges into robust, production-ready AI models, ensuring statistical integrity and operational reliability while managing end-to-end data pipe...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Innovate data solutions by developing complex reports and analyses to support senior management and client needs. Collaborate with teams to enhance data literacy and provide technical guidance across...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$89K - $125K *

Partner with us to integrate new firms into our IT environment, managing Microsoft 365 migrations and Active Directory consolidations while collaborating with cross-functional teams to ensure seamless...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$107K - $152K *

Transform the future of AI at scale by designing and deploying LLM-powered systems to enhance content quality and safety. Collaborate with a dynamic ML team to tackle complex challenges and make a mea...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$154K - $185K *

Lead the charge in developing advanced AI systems and automation platforms. Own multi-agent architectures and backend services that optimize workflows across teams, driving operational efficiency and...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$230K - $322K *

Accelerate progress at shaping foundational models and user understanding while collaborating with cross-functional teams to drive impactful machine learning initiatives and mentor top talent in a dyn...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$146K - $229K *

Lead a dynamic analytics team to create trusted measures, ensure actionable insights, and foster partnerships for data integrity and impact measurement across business functions...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$145K - $175K *

Transform the AI landscape by building a robust platform for seamless AI tool deployment, enhancing collaboration across teams while ensuring data governance and security. Drive innovation in applicat...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$145K - $170K *

Join a team that's redefining product strategy through advanced analytics. Leverage your expertise to drive insights, enhance product performance, and collaborate with stakeholders to make impactful b...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$320K - $405K *

Transform the future of data center engineering by resolving on-site technical issues, collaborating with contractors, and ensuring project success through effective problem-solving and communication...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$145K - $160K *

Pioneer data-driven insights by collaborating with cross-functional teams to enhance business strategies. Leverage advanced analytics and visualization skills to drive operational improvements and sup...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $375K *

Champion the evolution of Code Archaeology by owning methodologies, assets, and technical leadership. Drive large-scale modernization efforts while shaping market perspectives and ensuring quality in...

2 weeks ago

  •   11 - 15 years exp.  •   Business Services

$100K - $120K *

Drive strategic enhancements in AI-powered support tools to optimize customer interactions, ensuring high-quality responses through collaboration, analysis, and continuous improvement for superior use...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$113K - $188K *

Optimize security administration and reporting processes while collaborating with cross-functional teams to enhance data insights and compliance metrics. Drive effective use of Workday tools and ensur...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$80K - $100K *

Unlock insights through quantitative analysis and research, shaping energy policy scenarios while collaborating with stakeholders to enhance philanthropic grantmaking efforts and present findings thro...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$174K - $234K *

Shape the future of advanced analytics and AI, driving data-driven solutions across commercial, medical, and clinical operations. Collaborate cross-functionally to deliver insights, enhance decision-m...

RemoteRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$73K - $212K *

Lead innovative AI solutions and manage client accounts, ensuring exceptional results. Inspire and develop teams while leveraging advanced analytics to drive business growth and foster strong client r...

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$200K - $250K *

Drive client growth by leveraging industry insights and technical expertise to craft customized solutions that meet the diverse needs of Fortune 500 companies while collaborating across teams to enhan...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Join a team that's driving innovative paid media strategies and leveraging AI to optimize performance across multiple platforms. You'll lead campaign execution, budget management, and testing to enhan...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.