Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Director Continuous Improvement
$120K - $150K *
Champion continuous improvement initiatives by optimizing processes and products across the organization. Lead cross-functional teams to enhance operational efficiency, quality, and customer experienc...
3 weeks ago
$131K - $209K *
Engage with teams to deliver comprehensive AI enablement programs, designing tailored learning paths and fostering a culture of proficiency across all departments. Collaborate closely with HR to integ...
Reposted yesterday
Senior/Staff Attack Engineer, Rapid Response
$230K - $275K *
Lead the charge in vulnerability research and exploitation techniques, transforming real-world threats into automated solutions. Collaborate with teams to enhance security measures and validate defens...
4 weeks ago
Full-Stack Engineer - AI-Native Solutions
$98K - $163K *
Shape the future of enterprise software by building secure, scalable applications. Collaborate with cross-functional teams to integrate AI capabilities and deliver innovative solutions that meet busin...
Yesterday
$85K - $125K *
Contribute to acquiring and managing data partnerships, collaborating with product teams to prioritize and improve dataset quality, while leveraging AI to enhance data processes and achieve business o...
Reposted 3 weeks ago
Lead Infrastructure Engineer - Hybrid Cloud & Automation Solutions
$130K - $155K *
Optimize and implement scalable, secure infrastructure solutions across Windows, Citrix, AWS, and Azure. Drive automation and collaborate with teams to design zero-trust architectures, enhancing infra...
4 weeks ago
Engineering Manager - Servicing & Fulfillment
$166K - $193K *
Lead and mentor a team of engineers while overseeing technical excellence and driving AI innovation in operational systems. Collaborate cross-functionally to deliver impactful features for post-purcha...
Reposted 2 days ago
$110K - $130K *
Transform your career by building and scaling innovative growth strategies that empower Sales teams to engage effectively with customers, leveraging data, AI, and automation for measurable impact...
5 days ago
$95K - $115K *
Shape the future of HR technology by leading system administration and enhancements. Collaborate across departments to optimize processes, improve data accuracy, and drive innovation in HR systems, en...
Yesterday
$110K - $130K *
Elevate your career by implementing and supporting AWS cloud solutions in a dynamic environment. Collaborate with experts to optimize performance and ensure secure, scalable infrastructure for federal...
1 week ago
$90K - $110K *
Transform customer experiences by driving technical excellence in post-sale support. Collaborate with teams to ensure seamless handoffs, empower account managers, and resolve escalations, all while en...
1 month ago
Director, Technical Products and Operations
$200K - $235K *
Drive product excellence by owning the lifecycle and security of high-performance client SaaS platforms hosted on AWS. Lead a dedicated team to optimize operations, ensure compliance, and deliver seam...
Reposted 2 weeks ago
Sr Paid Search Strategist (Enterprise)
$75K - $90K *
Transform your career by leading strategic SEM campaigns that enhance online visibility and drive conversions. Collaborate with innovative clients, analyze data, and optimize performance to exceed goa...
3 weeks ago
Senior Copywriter, Performance Marketing
$127K - $223K *
Transform the way we communicate life insurance through compelling copy that captures attention and drives action. Collaborate with teams to create impactful Direct Mail and social media content that...
Reposted yesterday
$119K - $149K *
Lead full-cycle recruiting for technical and analytical roles, partnering with teams to define success and build diverse talent pipelines. Utilize creative sourcing and data-driven insights to enhance...
1 week ago
Solutions Engineer | East Coast | Remote
$182K - $226K *
Innovate with a dynamic team to solve customer challenges and drive growth. Leverage your technical expertise in pre-sales to enhance customer engagement and deliver impactful solutions in a fast-pace...
5 days ago
$110K - $130K *
Join a team that empowers customers to achieve their business goals through strategic guidance and hands-on support, enhancing their experience with our DevSecOps platform and driving long-term succes...
2 weeks ago
Principal Software Engineer, Workload Orchestration (Distributed Compute))
$165K - $215K *
Architect innovative solutions to complex technical challenges, driving platform direction and enabling deep specialists. You'll tackle high-leverage problems that define our future capabilities and e...
1 week ago
$73K - $182K *
Innovate design concepts while leading and mentoring a dynamic team. Collaborate cross-functionally, present ideas to clients, and drive strategic insights for impactful brand development across multi...
2 weeks ago
$130K - $155K *
Lead the AI/ML product strategy across multiple business units, driving integration and data-centric solutions that enhance customer value and revenue growth through innovative workflows and collabora...
1 week ago
$80K - $95K *
Partner with us to enhance industrial automation projects, collaborating with a diverse team to improve efficiency and quality through PLC and HMI systems, while gaining valuable experience in IT/OT n...
1 week ago
$95K - $115K *
Champion healthcare solutions by managing integrations and providing expert support. Drive projects and improve processes as a Senior Interface Analyst in a dynamic and innovative environment, ensurin...
Reposted 1 week ago
Security Operations Engineer II
$84K - $124K *
Drive the evolution of Cyber Defense by engineering and automating security operations, enhancing incident response, and maintaining enterprise security platforms to ensure robust protection and swift...
2 weeks ago
Director, Clinical Data Analytics
$203K - $304K *
Lead and innovate clinical data analytics and visualization strategies, transforming multi-source trial data into actionable insights. Manage a high-performing team to enhance decision-making across N...
Yesterday
$110K - $130K *
Lead the charge in transforming client operations by identifying and accelerating AI-driven opportunities. Collaborate with stakeholders to frame business challenges, prototype solutions, and drive me...
Reposted 1 week ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.