Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$110K - $130K *

Unlock potential by joining a dynamic team of Solution Consultants, delivering expert guidance on Atlassian products to help clients maximize their investments and achieve strategic outcomes in the Pu...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$210K - $256K *

Transform industry practices by leading large-scale AI and data initiatives, driving business growth and operational excellence within Consumer Products, Retail, and Logistics sectors...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Information Technology

$210K - $256K *

Lead the charge in driving strategic growth and transformation initiatives, leveraging AI and data expertise to elevate Consumer Products, Retail, and Logistics clients through tailored, impactful sol...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Information Technology

$120K - $145K *

Champion innovative database solutions by proactively optimizing performance and guiding clients on cloud strategies. Collaborate with teams to enhance mission-critical systems and ensure seamless ser...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$225K - $265K *

Elevate your career by transforming business workflows into efficient, automated systems. Collaborate with cross-functional teams to implement AI solutions that enhance productivity and drive measurab...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Accelerate your career by designing and optimizing secure, scalable cloud infrastructure. Collaborate with cross-functional teams to enhance operational efficiency and ensure high availability for glo...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

$140K - $187K *

Innovate the future of AI security by designing and implementing robust defenses against adversarial threats, ensuring the integrity of AI systems while fostering innovation and collaboration across c...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$62K - $100K *

Drive SaaS conversion initiatives by collaborating with teams to assess risks, readiness, and opportunities. Engage with customers to facilitate migrations and ensure effective communication throughou...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$99K - $110K *

Accelerate progress at winning new enterprise customers by leveraging your expertise in complex SaaS solutions. Drive revenue growth and build executive relationships while navigating intricate sales...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Media

$80K - $95K *

Transform customer data integration by configuring and validating mappings between third-party systems and applications. Collaborate with teams to ensure seamless onboarding and ongoing support, enhan...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Elevate audio ML research by designing workflows that automate experiments, enhance reproducibility, and optimize GPU resources. Collaborate with researchers to streamline processes and deliver impact...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Consumer Technology

$95K - $177K *

Join us to design and implement scalable data solutions that empower analytics and AI-driven insights. Collaborate with cross-functional teams to ensure high-quality data governance and support operat...

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Shape the future of laboratory operations by providing technical guidance, ensuring compliance with quality standards, and leading innovative projects to enhance testing protocols and methodologies wh...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of customer success by driving AI adoption through tailored solutions. Collaborate with enterprise teams to unlock high-impact use cases, ensuring measurable business value and operat...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$127K - $223K *

Analyze channel performance and drive data-driven decisions by building models, validating vendor claims, and proactively answering business questions to enhance offline and direct mail strategies...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$184K - $314K *

Elevate executive recruiting by leading VP-level searches, advising C-suite leaders, and shaping talent strategies. Drive high-impact hiring decisions while managing multiple confidential searches in...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Unlock potential by designing and optimizing cloud-based data platforms, ensuring scalability and performance across relational, NoSQL, and vector databases while collaborating with AI and engineering...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$113K - $170K *

Lead the charge in transforming customer integrations by driving technical discovery, scoping complex implementations, and ensuring successful onboarding for high-stakes accounts. Collaborate closely...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $92K *

Join our team to enhance healthcare quality through precise coding audits, mentoring coders, and driving process improvements. Your expertise will help shape compliance and accuracy in outpatient serv...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Transform the future of digital engagement by leading Adobe Target implementations. Collaborate across teams to develop personalized strategies that enhance user experiences and drive measurable busin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Transform the energy & utilities landscape by leading OT and infrastructure workstreams throughout the private equity investment lifecycle, driving diligence, integration, and value creation for criti...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$96K - $130K *

Join a dynamic team to shape innovative fundraising tools that empower progressive campaigns and nonprofits. Leverage modern technologies to enhance election readiness and compliance, while mentoring...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$99K - $139K *

Join a dynamic team to develop and maintain innovative web applications, enhancing user experience and security. Collaborate with stakeholders to gather requirements, create documentation, and ensure...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Drive regulatory strategy across major programs, leading high-impact submissions and authority engagement. Collaborate with cross-functional teams to optimize clinical development and ensure complianc...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $130K *

Unlock potential by leading complex data engineering initiatives, enhancing platform reliability, and mentoring junior engineers. Collaborate across teams to design and implement scalable solutions wh...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.