Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Average Salary: $106,884
Senior Regulatory Affairs Manager, Chemistry Manufacturing and Controls
$106K - $159K *
Transform regulatory strategies by providing CMC expertise to support product development and compliance in a dynamic pharmaceutical environment, ensuring quality and adherence to global standards thr...
2 weeks ago
Clinical Applications Specialist, Invasive Cardiology
$92K - $138K *
Help us enhance clinical education by delivering expert training and support to healthcare professionals. Drive product adoption and optimize user competencies while fostering strong relationships wit...
2 weeks ago
Clinical Application Specialist - General Imaging (NYC)
$110K - $165K *
Elevate your career by driving clinical education and training for GI Ultrasound. Collaborate with sales and customers to enhance technical competencies, optimize workflows, and improve patient care t...
2 weeks ago
$65K - $98K *
Champion growth in Alzheimer’s imaging sales by identifying leads, enhancing team efficiency, and collaborating with outside sales to drive referrals and expand market access for innovative healthcare...
2 weeks ago
Contrast Media Clinical Sales Specialist
$97K - $146K *
Partner with us to provide clinical support for contrast media, delivering education and product expertise to healthcare professionals while collaborating with internal teams to enhance patient care a...
2 weeks ago
Senior Director, Nonprofit and Arts & Cultural Customer Success
$150K - $204K *
Unlock potential by leading transformative customer success strategies for nonprofit and arts organizations. Drive retention, growth, and innovation through AI-enabled solutions while collaborating ac...
2 weeks ago
$101K - $132K *
Elevate your career by driving strategic partnerships with leading cloud providers. Collaborate across teams to enhance revenue growth and client satisfaction while managing key partner relationships...
2 weeks ago
Director, Portfolio Manager - Project Finance and Infrastructure
$93K - $217K *
Lead the charge in managing a complex project finance portfolio, partnering with clients and internal teams to ensure robust underwriting and risk management strategies in renewable energy and infrast...
Reposted 2 weeks ago
Commercial Portfolio Manager III-1
$95K - $115K *
Champion growth by managing a $100MM+ commercial portfolio, enhancing customer relationships, and mitigating risks while ensuring credit quality and compliance with established policies...
2 weeks ago
IT Business Analyst – Apptio TBM
$73K - $110K *
Lead impactful projects to enhance Apptio TBM solutions, driving cost transparency, benchmarking, and strategic planning through collaboration with IT and business partners in a fully remote environme...
Reposted 2 weeks ago
$95K - $115K *
Drive client success as a key Account Manager, managing relationships across diverse industries. Oversee project lifecycles, enhance client experiences, and help shape the client services function fro...
2 weeks ago
$200K - $230K *
Strategize and lead comprehensive marketing initiatives to drive customer acquisition, enhance brand presence, and support revenue growth across diverse business segments. Oversee a high-performing te...
2 weeks ago
Specialty Development Executive - Southeast Territory
$130K - $140K *
Empower healthcare providers by promoting innovative colorectal cancer screening solutions, delivering exceptional support and education while strategically expanding product adoption across a designa...
Reposted 2 weeks ago
$80K - $100K *
Accelerate business growth by owning the full sales cycle and expanding strategic partnerships with enterprise retailers. Leverage insights to consistently exceed revenue targets and drive impactful s...
Reposted 2 weeks ago
$150K - $200K *
Advance partner success by optimizing enablement strategies and driving revenue growth through data-driven insights and strategic program management in a collaborative environment...
2 weeks ago
$130K - $160K *
Lead the end-to-end customer onboarding process, managing cross-functional teams to ensure timely delivery and value realization. Collaborate with customers to provide expert guidance and drive succes...
2 weeks ago
Sr. Specialist Program Management
$95K - $115K *
Lead the charge in managing complex missile propulsion programs, driving execution from inception to completion. Collaborate with teams to achieve business objectives while ensuring technical performa...
2 weeks ago
(DoW SkillBridge), Supervisor, Operations Management
$80K - $95K *
Join a dynamic team as you oversee production activities, ensuring goals are met while prioritizing schedules and quality. Collaborate with team members to enhance efficiency and drive continuous impr...
2 weeks ago
Senior Director, Clinical Operations
$270K - $280K *
Join a team that's driving clinical excellence by overseeing trial execution, managing timelines, budgets, and CROs. Collaborate with stakeholders to ensure compliance and quality while mentoring team...
2 weeks ago
$110K - $130K *
Lead the accounting function, ensuring compliance and accuracy in financial reporting. Partner with the CFO to build scalable processes and controls, supporting growth in a multinational industrial en...
2 weeks ago
$100K - $140K *
Take ownership of building intelligent, cloud-native solutions that streamline radiology workflows. Collaborate with cross-functional teams to deliver reliable software, ensuring quality and security...
2 weeks ago
Director, Strategic Sales - South Central
$150K - $180K *
Join us to drive strategic sales growth across key verticals in the South Central U.S. Lead complex enterprise sales cycles, engage with C-suite stakeholders, and develop a robust pipeline to achieve...
2 weeks ago
$170K - $210K *
Engage in client development and system architecture while leading a team to enhance client satisfaction. Collaborate on solutions, mentor staff, and drive growth through effective communication and s...
2 weeks ago
Transportation Adjuster (Michigan)
$75K - $95K *
Unlock potential by navigating complex transportation claims with expertise, ensuring resolution while collaborating with clients, attorneys, and medical providers to uphold regulatory standards in a...
Reposted 2 weeks ago
Sr Field Application Engineer (TOLA)
$160K - $250K *
Transform customer experiences by leading technical sales solutions for wireless routers and managed services. Collaborate with partners and clients across diverse industries, ensuring optimal connect...
2 weeks ago
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.