Tango Therapeutics

Vice President, Marketing & Sales

Tango Therapeutics$301K — $452K *
Pharmaceuticals & Biotech
15+ years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in a scientific or business discipline required; MBA or advanced degree preferred.
  • 20+ years of progressive commercial leadership in biopharmaceuticals, with experience in large pharma and biotech.
  • Deep expertise in the oncology market, particularly with oral and precision therapies.
  • Demonstrated enterprise mindset with knowledge of drug development and regulatory pathways.
  • Proven track record of cross-functional leadership in a matrixed environment.

Responsibilities

  • Act as a key voice in corporate strategy alignment for broad commercial goals.
  • Collaborate with Clinical Development and Regulatory Affairs for clinical trial and product profile alignment.
  • Build partnerships across Medical Affairs, Market Access, and Finance for cohesive product positioning.
  • Design and scale marketing and sales infrastructure for commercial readiness.
  • Lead development of disease awareness campaigns and brand positioning.
  • Direct creation of a data-driven omnichannel engagement model for oncologists.
  • Define optimal field force strategy for oncology sales and ensure launch readiness.

Benefits

  • Hybrid work model with flexibility in work location.
  • Opportunity to lead in a transitioning biotech environment.
  • Engagement with cutting-edge precision oncology assets.
  • Collaborative culture promoting cross-functional teamwork.
  • Access to a high-performing, entrepreneurial environment.
Full Job Description
Summary

As Tango transitions into a fully integrated, commercial-stage biopharmaceutical organization, the Vice President of Marketing and Sales will serve as a core pillar of the Commercial Leadership Team. Reporting to the Chief Commercialization Officer, this executive will be responsible for architecting the overarching commercial strategy, establishing our market presence, and driving the successful launch of our precision oncology assets, starting with our oral PRMT5 inhibitors.

The ideal candidate brings an enterprise mindset and a proven track record of successfully launching oral oncology therapies. By combining the rigorous, scaled commercial discipline of large, established pharmaceutical organizations with the agility and entrepreneurial spirit of a fast-paced biotech, this leader will build a high-impact, scientifically driven commercial organization. Success in this role requires exceptional cross-functional leadership, guiding overarching corporate strategy, and ensuring seamless integration across commercial, scientific, and operational domains.

Your Role:

Enterprise Leadership & Cross-Functional Strategy
  • Corporate Strategy Alignment: Act as a critical voice on the leadership team, ensuring that commercial strategies are deeply integrated with the company's broader corporate goals, financial planning, and long-term vision
  • Regulatory & Development Partnership: Collaborate closely with Clinical Development and Regulatory Affairs to inform clinical trial designs, shape Target Product Profiles (TPPs), and align on label negotiation strategies and post-approval lifecycle management
  • Cross-Functional Synergy: Build seamless, highly collaborative partnerships across Medical Affairs, Market Access, Finance, and Corporate Communications to ensure unified product positioning and a cohesive narrative across all stakeholder touchpoints
  • Commercial Architecture: Design and scale the foundational marketing and sales infrastructure from the ground up, transitioning the organization from clinical-stage to commercial readiness while maintaining a lean, high-performing culture

Marketing Strategy & Brand Leadership
  • Brand & Disease State Positioning: Lead the development of compelling disease awareness campaigns, scientific narratives, and pre-launch brand positioning that clearly communicate the value of our precision oncology assets
  • Omnichannel Strategy: Direct the creation of a robust, data-driven digital and non-personal engagement model tailored to the specific behaviors and preferences of medical oncologists and academic centers
  • Market Insight & Competitive Intelligence: Drive comprehensive market research initiatives to anticipate shifts in the oral oncology landscape, deeply understand patient journeys, and continuously refine commercial strategy based on real-time data

Sales Strategy & Execution
  • Field Force Architecture: Define the optimal field force sizing, territory alignment, and deployment strategy for a highly specialized oncology sales team
  • Launch Readiness: Drive the operational and strategic readiness of the sales organization, ensuring rigorous training and certification of the field team on the complex science behind biomarker-driven treatments
  • Customer Engagement: Cultivate and maintain executive-level relationships with Key Opinion Leaders (KOLs), academic oncology networks, and major community oncology practices to drive scientific share of voice


What you bring:
  • Bachelor's degree in a scientific or business discipline required; MBA or advanced scientific degree (PharmD, PhD) strongly preferred
  • 20+ years of progressive commercial leadership experience in the biopharmaceutical industry, with a mandatory blend of experience in large, established pharmaceutical organizations (best practices, scale, strategic rigor) and biotech environments (agility, foundational buildout, resource optimization)

Core Competencies
  • Oncology Expertise: Deep expertise in the oncology market is required, with a strong track record of launching and commercializing oral oncology and precision/biomarker-driven therapies
  • Enterprise Mindset: Demonstrated ability to think beyond the commercial function, understanding the complexities of drug development, regulatory pathways, and corporate finance to drive holistic company success
  • Cross-Functional Leadership: Proven experience successfully partnering with R&D, Regulatory, and Medical Affairs in a highly matrixed, science-first environment
  • Culture & Team Building: Exceptional track record of attracting, developing, and retaining top-tier commercial talent while fostering a collaborative, patient-centric, and performance-driven culture


#LI-Hybrid

Salary range

$301,600-$452,400 USD

About Tango Therapeutics

Tango Therapeutics is a biotechnology company that develops targeted cancer therapies. The company's approach is based on a deep understanding of the genetic drivers of cancer, and it uses this knowledge to develop drugs that can selectively target cancer cells. Tango Therapeutics was founded in 2017 and is headquartered in Cambridge, Massachusetts. The company has partnerships with a number of other biotech and pharmaceutical companies, and it has received funding from a variety of sources, including venture capital firms and government agencies.
Learn more about Tango Therapeutics
Size
51 employees
Market Cap
$617.3 million
Industry
Founded
2017
NASDAQ

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