Position Overview
TheVice President, Global Commercial StrategyLead for Inflammation & Immunology (I&I) and Rare Disease is responsible for driving long-range commercial strategy, portfolio management, and commercial success across both pipeline and inline brands. This role serves as thesingle, authoritative commercial voice to R&D, Business Development, and US & International Commercial Regions,establishingclear commercial leadership to improve portfolio decision-making and trade-offs, ensure optimal launch and brand marketing strategies, and maximize global patient impact and enterprise value realization for our I&I and Rare Disease portfolio.
Reporting to the Global Commercial Strategy Lead, this leader shapes decisions on I&I and Rare Disease portfolio prioritization, lifecycle value optimization, and global marketing strategy. The position partners closely with R&D, Medical Affairs, Global Access & Value, and Regional Commercial teams to deliver breakthrough therapies addressing autoimmune, inflammatory, and rare diseases.
Success in this role requires a senior commercial strategist who combines scientific depth with decisive enterprise leadership. This leader must confidently engage in complex scientific and clinical discussions, synthesize insights across R&D, Access, and Commercial teams, and convert them into clear portfolio priorities and differentiated global strategies. With full accountability for value creation, the role requires strong P&L acumen and the ability to make disciplined tradeoffs that optimize lifecycle value, launch success, and longterm portfolio performance.
The I&I and Rare Disease portfoliorepresentssignificant strategic value to realizing Pfizer's vision to achieve leadership via breakthroughs in prioritized diseases and biological axes to generate highly differentiated, multi-indication mega-blockbusters. Today, the portfolio delivers more than $10B globally with 22 ongoing clinical studies underway to significantly expand our product portfolio over the next several years.
Role Responsibilities
1. Long-Range Strategic Planning & Portfolio Management
- Develop and execute comprehensive long-range commercial and marketing strategies for I&I and Rare Disease portfolios, encompassing pipeline assets from early development to in-line assets through commercial maturity.
- Serve as single, authoritative commercial voice to R&D, Commercial Regions, and Business Development strengthening commercial input from early development through launchvia participation in I&I Strategy Governance Team to influence clinical development plans and investment decisions.
- Lead development of business cases for new product launches and lifecycle management investments.
2. Launch Excellence & Commercialization Strategy
- Lead integrated global launch and marketing strategies coordinating cross-functional teams across R&D, Commercial Regions, Medical, Regulatory, Market Access, and Supply.
- Drive new product and indication launch readiness planning including market development activities, brand positioning, competitive assessments, and HCP/patient unmet need analysis.
- Own commercial asset lifecycle strategy for I&I and Rare Disease including implications of new indications and competitive dynamics
3. Commercial Excellence & Brand Strategy
- Raise the bar on marketing impact, quality, and brand performance byestablishingconsistently higher, impact-driven standards for strategic outputs and creative excellence
- Lead proactive market shaping in moments that matter,anticipatingand addressing threats with pre-emptive strategies.
- Steer Commercial prioritization of evidence generation strategies across lifecycle and Regions to enable sharper cross-functional decisions and portfolio value maximization.
4. Cross-Functional Leadership & Governance
- Provide global strategic direction for in-line assets while enabling regional adaptation and tactical alignment.
- Own global brand strategy, launch plans, lifecycle management, and core content packages
- Partner with Global Access & Value (GAV) teams to develop pricing, contracting, and market access strategies that maximize global value of our portfolio.
5. Organizational Leadership & Talent Development
- Build and lead high-performing Global Commercial Strategy organization of 50+ highly engaged colleagues.
- Embed culture of cross-functional collaboration ensuring coordinated internal and external stakeholder engagement.
- Develop future commercial leaders with the capability to operate across full span of commercial development, launch, and inline commercialization.
Qualifications & Experience
Education
- Bachelor's degree in Life Sciences, Business, Marketing, or related fieldrequired
- MBA or other advanced degree (PhD, MD, PharmD) strongly preferred
Professional Experience
- Minimum15+ yearsof successful, progressive marketing, commercial, and/or development experience in pharmaceutical or biotechnology industry
- Minimum 8-10 yearsin commercial leadership roles including Global/US/International marketing, commercial development/strategy
- Experience in both pipeline (pre-launch) and inline (post-launch) brand managementspanning early development through commercialization
Therapeutic Area & Functional Expertise
- Brand management experiencedeveloping product strategies, positioning programs, and go-to-market plans
- Product launch experienceincluding global launch planning and execution
- Portfolio management and strategic planningexpertiseacross multiple therapeutic areas and development stages
- Demonstrated ability to influence complex development decisions and engage deeply in scientific dialogue.
Leadership & Organizational Capabilities
- Second-line leadership experiencewith accountability for developing and managing senior leaders
- Demonstrated ability to lead cross-functional teams and influencing without direct authoritywhile managing complex stakeholder environments
- Track recordofbuilding and developing high-performing teams
Strategic & Business Acumen
- Strategic thinking and vision-settingcapabilities with ability to translate into executable plans
- Financial and business acumenincluding forecasting, business case development, and investment prioritization
- Understanding ofmarket access dynamics, payer strategies, and value demonstration
- Strong enterprise mindset, with proven P&L leadership capability and executive presence
Location
- New York, Collegeville, Cambridge; other global Pfizer Commercial locations considered on a case-by-case basis
Physical/Mental Requirements
- Comfort working in a fast-paced environment and making complex decisions quickly
- Ability to leverage AI models, synthesize and analyze complex data, and understand trends and mathematical calculations
- Ability to travel domestically and internationally as needed for congresses, sales meetings and customer interactions
Non-standard Work Schedule Travel or Environment Requirements
- Pending Pfizer policies, travel is required: Domestic or International travel of up to 25%
Other Job Details:
Last Day to Apply: May 31, 2026
Location: Selected Candidate must be onsite 2.5x weekly, travel to NYHQ & Cambridge on a regular basis.
The annual base salary for this position ranges from $313,100.00 to $521,900.00. In addition, this position is eligible for participation in Pfizers Global Performance Plan with a bonus target of 35.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of lifes moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Manufacturing
