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Position title: Technologist

Duration: Fixed Term Contract - July 2027

Location: Toronto, ON

Main Responsibilities:

1.Detoxification and Purification of Diphtheria Toxin/Toxoid

• Primary operator for the validated cleaning, rinsing of process related equipment.
• Primary operator for the preparation, inspection and release of purification equipment for toxin/toxoid processing.
• Primary operator for the recovery of ammonium- sulphate precipitated toxin using crude filtration with a secondary operator.
• Primary operator for the dyalisis of toxin using membrane dyalisis for ammonium sulphate removal in cold room.
• Primary operator for the detoxification of the toxin with a secondary operator.
• Set-up, operate and monitor the complex ultra-filtration unit with a secondary operator.
• In-house testing and preparation of critical QO release tests.
• Set-up and perform critical sterile filtration of tpxin/toxoid with a secondary operator.
• Calibration of pH meters, conductivity meters, scales and balances.
• Perform environmental monitoring as required.
• Complete monitor and review TR results and BPRs.
• Primary operator for the entry of tests samples in LIMS/OASIS systems.
• Execution of Validation protocols for in-house testing procedures in conjunction with secondary technologist.

2. Purification of Tetanus Toxoid

• Primary operator for the validated cleaning, rinsing of process related equipment.
• Primary operator for the preparation, inspection and release of purification equipment for toxin/toxoid processing.
• Primary operator for the recovery of ammonium- sulphate precipitated toxin using crude filtration with a secondary operator.
• Primary loading, balancing and operation of centrifuges.
• Set-up, operate and monitor the complex ultra-filtration unit with a secondary operator.
• In-house testing and preparation of critical QC release tests.
• Calibration of pH meters, conductivity meters, scales and balances.
• Perform environmental monitoring as required.
• Review and verify work performed by others, provide assistance to other technologists for completion of processes. Complete, monitor and document TR results, document BPRs and prepare product for area release.
• Trouble shooting problems arising within processes. Strong understanding of ultra-filtration, dia-filtration, sterile filtration, equipment integrity and testing (including pre-testing).
• Entry of tests samples in LIMS/OASIS system.

3. Preparation of stock and bulk Tuberculin PPD

• Primary operator for the inspection and release of purification equipment for toxin/toxoid processing.
• Primary preparation of hazardous diluents, critical final filters and process related equipment for PPD production.
• Primary inspector for the process related equipment prior to use.
• Formulation and sampling of non-replaceable (dry powder can not be replaced) stock solution and final bulk in clean room with a secondary technologist.
• Complete, monitor and review TR results and BPRs.

4. Purification, clean room and toxin recovery area monitoring and tetsing

• Primary preparation of QO approved disinfectants for cleaning applications.
• Primary preparation of rooms (including clean rooms) for sampling and environmental monitoring.
• Prepare and sample EM as outlined by SOP. Monitor and perform EM as required per product, per week, per bi-week, per month.
• Entry of EM in Master.
• Recovery of the completed EM documents.
• Primary verification to routine facility EM schedules independent to the production requirements.
• Monitor refrigerators and incubators.
• Access FMS for facility status.

5. Documentation of activities and SPC data entry

• Concurrent BPR entry and checking of calculations.
• Data entry into SPC database for SPC trending.
• Organization of batch records.
• Monitoring of cleanroom, incubator and refrigerator logs.
• Information retrieval for inspections, validation etc.
• Review SOPs every three years and update. Create new SOP if needed.
• Documentation and tracking of reference samples.

6. SAP and EM Data Entry

• Data entry for SAP manufacturing processes and maintenance orders.
• Issuance and creation of process orders.
• Maintenance of material adjustment forms.
• Maintenance of inventory.
• Re-order of non-MRP items required for production activities.
• Use of e-shopping, NON conformance creation and addressing, FM work requests.
• EM data entry for MASTER EM system.

No employee has a proprietary right to an activity or group of activities.

Activities may be changed or reassigned to meet the needs of the operations.

About You

Education:

• Minimum three (3) years College Diploma and University degree (Biology, Chemistry, Physics and Laboratory related courses), plus a minimum of one 12-18 months of previous relevant work experience.
• Preferred four (4) years Bachelor's degree (Microbiology, Bio-chemistry), plus a minimum of 6-12 months of previous relevant work experience.

Skills and Knowledge:

1.Functional, technical or scientific

• Aseptic and Clean room Techniques.
• Protein purification.
• Quality operations.
• Mechanical & processing techniques.
• Chemistry/Microbiology.
• Computers.
• Mathematics, Statistical, Analytical/Deductive reasoning.

2.Supervisory, Managerial and Personal

• Coordinating.
• Organization.
• Verbal communication.
• Judgement/ Personal Empowerement.
• Written communication.
• Instructing.
• Teamwork.

Hours Of Work:

• Inclusive from Monday to Friday 8:00 AM - 4:00 PM.

This is subject to change at any time and it should not be construed as limiting the right of the company to make such a change to meet the requirements of the operation.

Mandatory Application Requirement: Your Workday application form must be complete, and a copy of your resume MUST be attached in the Workday application form, at the time you submit your Workday application, otherwise your application will not be considered for this position

This position is for a current vacant role that is now open for applications.

Pay rate - $48.02 per hour

AI Usage

"Artificial Intelligence" refers to any systems that use automated processes, including algorithms and machine learning, to analyze data and make predictions, inferences, decisions, or recommendations without direct human involvement. These systems may process personal information to identify patterns, improve services, or support decision-making. The Company may use Artificial Intelligence for purposes including, but not limited to, resume screening and hiring, scheduling interviews or meetings, conducting surveys, matching skills with potential job openings, interview scoring, ensuring compliance with regulations applicable to our industry, and activities related to performance evaluation. Information collected and processed by the Company's Artificial Intelligence systems may include the personal information detailed above and calendar availability. It excludes the information collected and processed for monitoring purposes. You should contact Human Resources if you have a question or concern regarding your personal information. You can also contact Canada's Privacy Officer via Sanofi's data subject request portal, Data Subject Rights Webform. The Data Subject Rights Webform can also be used to request access or correction of your personal information and file a complaint.

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