Roche

Sr. Data Expert, Data Engineer (Clinical & Multimodal Data Integration)

Roche$119K — $222K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • PhD in Bioinformatics, Data Science or related field with 2+ years experience, or Master's with 3-6 years, or Bachelor's with 5+ years.
  • Hands-on experience with clinical data and scientific modalities like sequencing or imaging.
  • Proficient in Python (Pandas) and SQL; experienced with scientific data formats such as FASTQ and DICOM.
  • Familiar with workflow orchestration tools like Airflow or Snakemake and version control with Git.
  • Strong emphasis on data quality and experience with multidisciplinary teams.

Responsibilities

  • Lead integration and harmonization of multimodal scientific datasets using industry standards.
  • Own the end-to-end delivery of high-quality analysis-ready datasets.
  • Develop scalable workflows for data ingestion and quality control across diverse sources.
  • Collaborate with computational scientists to translate scientific needs into data solutions.
  • Implement validation frameworks to enhance data quality and discoverability.
  • Support AI initiatives by preparing metadata-rich datasets for analysis.

Benefits

  • Health, dental, and vision insurance.
  • Retirement plan options with company matching.
  • Paid time off and parental leave.
  • Continuing education and professional development opportunities.
Full Job Description

The Opportunity:
We are seeking a Sr. Data Expert, Data Engineer to lead the integration and delivery of clinically anchored, multimodal scientific datasets spanning clinical, sequencing, imaging, proteomics, and other emerging data modalities.
In this role, you will:

  • Lead the integration and harmonization of clinical and multimodal scientific datasets, applying industry data standards and metadata frameworks to improve interoperability and scientific usability.

  • Own end-to-end data delivery by designing, validating, documenting, and delivering high-quality, analysis-ready datasets that support research, AI/ML, and computational biology initiatives.

  • Develop scalable data workflows that automate data ingestion, quality control, transformation, and metadata management across diverse scientific data sources.

  • Partner with computational scientists, bioinformaticians, and data engineers to understand scientific requirements and translate them into scalable, reusable data solutions.

  • Drive data quality and continuous improvement by implementing validation frameworks, metadata standards, and AI-assisted data curation practices that improve data discoverability and reuse.

  • Support emerging AI and foundation model initiatives by preparing interoperable, metadata-rich datasets optimized for downstream analytics and machine learning applications.


Who You Are:

  • You have a PhD with 2+ years, a Master's degree with 3 6 years, or a Bachelor's degree with 5+ years of experience in Bioinformatics, Data Science, Biomedical Engineering, Computer Science, Clinical Sciences, or a related discipline, with experience working with clinical, biomedical, or scientific datasets.

  • You have hands-on experience integrating clinical data with one or more scientific modalities, including sequencing, imaging, proteomics, or other omics datasets, and understand clinical data models and longitudinal patient data.

  • You are proficient in Python (Pandas), SQL, and scientific data processing, with experience working with scientific data formats such as FASTQ, BAM/CRAM, VCF, DICOM, AnnData, or Parquet, and familiarity with cloud data platforms (AWS or GCP).

  • You have experience developing or supporting automated data pipelines using workflow orchestration tools such as Airflow, Nextflow, Snakemake, or Prefect, and are comfortable using Git for collaborative software development.

  • You are a collaborative problem solver with a strong focus on data quality, metadata management, and scientific reproducibility, and enjoy partnering with multidisciplinary teams to deliver scalable data solutions.

Preferred Qualifications:

  • Experience with clinical data standards such as CDISC (SDTM/ADaM), OMOP, or FHIR.

  • Experience integrating multimodal datasets (e.g., clinical + genomics, imaging + transcriptomics, or multi-omics).

  • Familiarity with biomedical ontologies, controlled vocabularies, FAIR data principles, and metadata standards.

  • Experience preparing scientific datasets for AI/ML workflows or foundation model development.

  • Experience supporting translational research, biomarker discovery, or drug discovery programs.

Onsite presence, on our South San Francisco campus, is expected for at least 3 days a week.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of California is $119,800 - $222,400. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

#LI-JD1

#ComputationCoE

About Roche

Roche Holding AG is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has bearer shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the largest pharmaceutical company in the world, and the leading provider of cancer treatments globally. The company also produces a range of diagnostic tests for medical professionals and patients. Roche was one of the first companies to bring targeted treatments to patients. In 2019, Roche had over 100,000 employees worldwide, and generated revenue of CHF 61.5 billion.
Learn more about Roche
Size
100,920 employees
Industry
NASDAQ

Similar Jobs

More Jobs at Roche

More Pharmaceuticals & Biotech Jobs

Find similar Sr. Data Expert, Data Engineer (Clinical & Multimodal Data Integration) jobs: