The AWS HealthOmics Workflow Orchestration team owns the runtime engine that executes genomic workflows at massive scale. We manage the full lifecycle of workflow execution, including task queuing, scheduling to provisioned compute resources, container orchestration, and connectivity management, enabling biopharmaceutical companies and research institutions to process clinical diagnostic and R&D workloads on AWS. When a clinician orders a genomic test for cancer detection or hereditary disease screening, our infrastructure ensures those results are delivered accurately and on time.
We are seeking a Software Development Manager who is passionate about applying AWS compute infrastructure to solve real-world bioinformatics challenges. Our service has experienced triple-digit growth for multiple years, and we need leaders who can drive down execution time while scaling to meet rapidly increasing customer demand. If you thrive at the intersection of distributed systems, infrastructure at scale, and life sciences, and want to lead a team delivering technology that directly impacts patient care decisions, this is the place for you.
Key job responsibilities
As a Software Development Manager (SDM) in AWS HealthOmics, you'll lead a team of 12 software engineers building and operating the orchestration layer that powers genomic workflow execution across AWS compute infrastructure. You will own the systems that schedule bioinformatics tasks to EC2 resources, manage container lifecycles, and ensure workflow resiliency at scale, all while meeting the stringent security and compliance requirements of a HIPAA-eligible service handling sensitive patient genomic data.
You will drive the technical strategy for scaling our orchestration infrastructure, reducing workflow execution overhead, and extending batch and connectivity capabilities for enterprise customers. You'll partner closely with infrastructure, product, and science teams, and engage directly with customers to understand their workflows and translate their needs into large product improvements that deliver measurable impact. You should be comfortable leading through ambiguity, making data-driven architectural decisions, and balancing the competing demands of scaling infrastructure, operational health, and new feature delivery.
The ideal candidate has experience managing teams that build and operate distributed systems at scale, ideally involving compute orchestration, container management, or workflow scheduling. You bring clarity to ambiguous problems, foster a culture of operational rigor, and believe that proactive investment in reliability and developer productivity compounds over time. Experience in life sciences or bioinformatics is a plus, but a deep interest in the domain and a track record of delivering infrastructure services on AWS is what matters most.
BASIC QUALIFICATIONS
- 3+ years of engineering team management experience
- 7+ years of working directly within engineering teams experience
- 3+ years of designing or architecting (design patterns, reliability and scaling) of new and existing systems experience
- 8+ years of leading the definition and development of multi tier web services experience
- Knowledge of engineering practices and patterns for the full software/hardware/networks development life cycle, including coding standards, code reviews, source control management, build processes, testing, certification, and livesite operations
- Experience partnering with product or program management teams
PREFERRED QUALIFICATIONS
- Experience in communicating with users, other technical teams, and senior leadership to collect requirements, describe software product features, technical designs, and product strategy
- Experience in recruiting, hiring, mentoring/coaching and managing teams of Software Engineers to improve their skills, and make them more effective, product software engineers
- Experience with bioinformatics workflow languages and execution frameworks (e.g., Nextflow, WDL, CWL) and familiarity with production genomics pipeline orchestration, including containerized task execution, dataflow-driven scheduling, and reproducible workflow portability across compute environments.
The base salary range for this position is listed below. Your Amazon package will include sign-on payments and restricted stock units (RSUs). Final compensation will be determined based on factors including experience, qualifications, and location. Amazon also offers comprehensive benefits including health insurance (medical, dental, vision, prescription, Basic Life & AD&D insurance and option for Supplemental life plans, EAP, Mental Health Support, Medical Advice Line, Flexible Spending Accounts, Adoption and Surrogacy Reimbursement coverage), 401(k) matching, paid time off, and parental leave. Learn more about our benefits at https://amazon.jobs/en/benefits.
USA, WA, Seattle - 184,900.00 - 250,200.00 USD annually