Foresite Labs

Senior Staff Engineer, Bioinformatics

Foresite Labs$202K — $215K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Ph.D. in computational biology, computer science, statistics, genomics, or related field
  • 6+ years of professional experience in bioinformatics or closely related roles
  • Ability to distinguish biological signal from technical noise using various statistical, machine learning and deep learning methodologies
  • Proficiency in programming languages for scalable production multi-omic analyses
  • Experience developing reproducible workflows in cloud or HPC environments
  • Experience optimizing compute costs at scale (preferred)
  • Experience developing commercial products (preferred)

Responsibilities

  • Analyze large-scale multi-omic data to identify technical artifacts versus biological signals.
  • Design and implement innovative computational methods for improved signal detection.
  • Develop and maintain robust analysis pipelines for data processing.
  • Build and optimize reproducible workflows in cloud and HPC environments.
  • Identify and mitigate technical artifacts through thorough analysis.
  • Collaborate with wet-lab scientists to troubleshoot assay artifacts.
  • Communicate analytical findings effectively and support technical decision-making.

Benefits

  • Comprehensive health benefits package
  • Flexible work schedule
  • Professional development opportunities
  • Collaborative work environment
  • Access to cutting-edge technologies and resources
Full Job Description
Job Title: Senior Staff Engineer, Bioinformatics

Location: San Diego, CA

Job Type: Full-Time

Salary $202,000-$215,000

Position Overview

The SeniorStaff Engineer, Bioinformatics will develop, advance, and support large-scale analysis of multi-omic data, through application of existing and novel methods. They will be responsible for developing scalable pipelines for cloud and HPC environments. The ideal candidate combines strong expertise in data science and software development, along with the ability to work cross-functionally with wet-lab and commercial teams.

Key Responsibilities
  • Analyze large-scale multi-omic data to delineate technical artifacts from biological signals.
  • Design and implement novel computational methods to improve signal detection and reduce compute costs.
  • Develop and maintain robust analysis pipelines.
  • Build and optimize reproducible workflows in cloud and HPC environments with attention to cost and scalability.
  • Identify and resolve technical artifacts through cohort-level and assay-aware analysis.
  • Partner with wet-lab scientists to diagnose and address assay artifacts.
  • Communicate findings clearly and contribute to technical decision-making.

Qualifications

Education:
  • Ph.D. in computational biology, computer science, statistics, genomics, or related field


Required:
  • 6+ years of professional experience in bioinformatics or closely related roles.
  • Ability to distinguish biological signal from technical noise using a variety of statistical, machine learning and deep learning methodologies.
  • Proficiency in programming languages frequently used for both ad hoc and scalable production multi-omic analyses.
  • Experience developing reproducible workflows in cloud or HPC environments.

Preferred:
  • Experience optimizing compute costs at scale
  • Experience developing commercial products

About Foresite Labs

Foresite Labs is a venture capital firm that invests in early-stage healthcare and life sciences companies. The firm was founded in 2019 by Jim Tananbaum, a healthcare entrepreneur and investor. Foresite Labs is a subsidiary of Foresite Capital, a leading healthcare investment firm. The firm's portfolio includes companies in the areas of biotechnology, medical devices, digital health, and healthcare services. Foresite Labs provides funding, strategic guidance, and operational support to its portfolio companies. The firm is based in San Francisco, California.
Learn more about Foresite Labs
Industry
Founded
2019

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