AbbVie

Senior Scientist I - Cell Line Development

AbbVie$100K — $130K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in a scientific field with 10+ years of experience; Master's with 8+ years; or PhD with 0-2 years.
  • Strong background in cell biology and molecular biology, particularly in mammalian cell culture.
  • Experience with CHO cell culture and optimization is highly desirable.
  • Familiarity with regulatory filing and documentation standards preferred.
  • Experience with modern technologies like omics, CRISPR, NGS, systems biology, AI, ML, and modeling methods is a plus.
  • Demonstrated ability to design and execute experiments with data interpretation.
  • Proven record of teamwork and adaptability in diverse environments.

Responsibilities

  • Develop, characterize, and optimize CHO production cell lines for pipeline progression.
  • Apply cell line development strategies to advance robust clones with desirable productivity.
  • Implement advanced technologies to improve cell line development workflows.
  • Conduct independent laboratory research, troubleshooting experiments and methods as needed.
  • Communicate scientific ideas effectively to varied audiences.
  • Author and review technical reports, and contribute to project teams.
  • Collaborate with cross-functional teams to support project timelines and deliverables.
  • Manage multiple projects in a dynamic team environment.

Benefits

  • Comprehensive benefits package including paid time off (vacation, holidays, sick days).
  • Medical, dental, and vision insurance available.
  • 401(k) plan with company matching for eligible employees.
  • Participation in short-term incentive programs.
Full Job Description
We are seeking a highly motivated senior scientist to join our multidisciplinary team focused on developing robust production cell lines to enable AbbVie's clinical and commercial biologics pipeline. In this lab-based position, the senior scientist will contribute to the development, characterization, and optimization of mammalian host and production cell lines, with a strong emphasis on CHO-based cell line development to support enhanced recombinant protein productivity, improved product quality, and streamlined process efficiency. The successful candidate will play a key role in advancing the Biologics pipeline through cell line development, clone characterization, and collaboration with cross-functional teams. Experience with modern technologies such as CRISPR-Cas9, Cas-Clover, NGS, omics, bioinformatics, systems biology, artificial intelligence (AI), machine learning (ML), high-throughput automation, and digitalization for cell line and process optimization is highly desirable. Responsibilities: 3 Develop, characterize, and optimize CHO host and production cell lines to support pipeline progression and improve process performance. 3 Apply cell line development strategies to identify, evaluate, and advance robust clones with desirable productivity and product quality attributes. 3 Support implementation of advanced technologies to accelerate cell line development workflows and improve decision-making. 3 Conduct laboratory research independently, including troubleshooting of experiments, methods, and equipment as needed. 3 Apply creative and analytical thinking to solve complex scientific problems and communicate ideas effectively to diverse audiences. 3 Author and review technical reports; present data to the team and leadership; review literature; and contribute scientific insights to project teams. 3 Serve as the CLD representative on cross-functional teams and collaborate closely with cell line development, cell culture, analytical, purification, bioinformatics, and other functional colleagues to support project timelines and deliverables. 3 Manage multiple projects across therapeutic programs in a dynamic and fast-paced team environment. 3 Contribute to continuous improvement of cell line development platforms, workflows, and technologies. Qualifications 3 Bachelor's degree in a scientific field with at least 10 years of related work experience; Master's degree in a scientific field with at least 8 years of related work experience; or PhD in a scientific field with 0-2 years of related work experience. 3 Strong background in cell biology, molecular biology, and cell line development, with extensive experience in mammalian cell culture and aseptic technique. 3 Experience with CHO cell culture, clone screening, stability assessment, productivity characterization, and/or cell line optimization is highly desirable. 3 Working knowledge of regulatory filing expectations, documentation standards, and support for submission-ready cell line development packages is preferred. 3 Experience with omics, genetic engineering, flow cytometry, fluorescence-activated cell sorting (FACS), next-generation sequencing, bioinformatics, systems biology, machine learning (ML), artificial intelligence (AI), and/or modeling methods is a plus, but not the primary focus. 3 Demonstrated ability to independently design and execute experiments, interpret data, and identify appropriate follow-up strategies. 3 Proven track record of teamwork, adaptability, innovation, initiative, and integrity; global mindset to thrive in a diverse culture and environment. 3 Ability to work effectively with diverse internal and external collaborators. 3 Ability to multitask and deliver within timelines in a dynamic, fast-paced setting. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 3 The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. 3 We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. 3 This job is eligible to participate in our short-term incentive programs. Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

About AbbVie

AbbVie develops pharmaceuticals and medical devices. They provide products and services to therapeutic areas including immunology, oncology, neuroscience, eye care, virology, women's health, and gastroenterology.

AbbVie Careers

Joining AbbVie means becoming part of a global team dedicated to making a remarkable impact on patients' lives. At AbbVie, our employees are united in the pursuit of groundbreaking innovation and are committed to transforming the future of healthcare with leading-edge science.

Work You’ll Do

At AbbVie, you’ll collaborate with some of the brightest minds in the industry to solve challenging problems that have a high impact on society. Our culture fosters growth and embraces leadership and diversity training, ensuring that every team member can thrive.

Explore Job Opportunities

AbbVie offers a wide range of job opportunities and career paths, providing a platform where professionals can propel their careers forward. From research and development to marketing and sales, the potential to make a significant impact is limitless.

Internship Programs

Kickstart your career with an AbbVie internship. Our programs provide invaluable industry experience and a chance to develop essential skills in a real-world setting. Interns at AbbVie are considered integral members of the team and are given tasks that are both challenging and rewarding.

Professional Growth and Development

We believe in nurturing our team's professional growth through comprehensive training programs, leadership development opportunities, and continuous learning. Our commitment to your career growth is reflected in our robust offerings that enhance your skills and knowledge.

Benefits and Culture

AbbVie is dedicated to supporting our employees' well-being both inside and outside of work. Our benefits package includes health, financial, and social benefits that are designed to support the diverse needs of our employees. Our inclusive culture encourages collaboration and innovation, fostering a workplace where all can excel.

Hiring Process

Our hiring process is designed to ensure a match that will be beneficial both for the company and for your career aspirations. From resume submission to interview, each step is an opportunity to showcase your skills and fit with the AbbVie team.

Networking and Career Advancement

At AbbVie, networking doesn’t just enhance your career; it propels it. We encourage our employees to engage internally and externally to build relationships that foster personal and professional growth.

Join Our Team

Search open positions that match your skills and interests. We are looking for passionate, curious, and innovative team players who are ready to make a difference.

Stay Connected

Keep up to date with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here.

Job Alert Emails

Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding opportunities that await at AbbVie.

Explore AbbVie Jobs

Whether you’re seeking to advance your career in a dynamic and empowering environment, or looking for a place where you can innovate, lead, and contribute to something bigger, AbbVie is the place for you. Join us in our mission to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow.
Learn more about AbbVie
Size
50,000 employees
Market Cap
$288.5 billion
Industry
Net Income
$4.6 billion
Founded
2013
5 Year Trend
+17%
Revenue
$45.8 billion
NASDAQ

Similar Jobs

More Jobs at AbbVie

More Pharmaceuticals & Biotech Jobs

Find similar Senior Scientist I - Cell Line Development jobs: