AstraZeneca

Senior Director, Medical Evidence Strategy

AstraZeneca$243K — $365K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Doctoral degree (PhD/PharmD) or MSc/MPH in Epidemiology or Public Health with 10+ years of relevant experience.
  • Direct people management experience required.
  • Proven track record of strategic and tactical evidence planning.
  • Extensive hands-on experience in clinical/observational research and drug development.
  • Exceptional communication skills in English, with ability to work in multicultural environments.
  • In-depth knowledge of drug life cycle management and health care systems.
  • Expertise in Respiratory or Immunology therapeutic areas is a plus.

Responsibilities

  • Lead the development of Medical Evidence Strategy in collaboration with Medical Affairs Leads.
  • Identify evidence requirements and priorities based on clinical practice and disease knowledge.
  • Implement sustainability and health policy objectives within the medical strategy.
  • Develop and oversee brand-specific Medical Evidence tactical plans, ensuring timeliness and high scientific quality.
  • Serve as scientific lead for evidence studies, utilizing appropriate design and analytical methods.
  • Ensure adherence to governance procedures for medical studies as outlined by SOPs.
  • Communicate evidence effectively to senior leadership and external stakeholders.

Benefits

  • Qualified retirement program (401k plan).
  • Paid vacation and holidays.
  • Paid leaves.
  • Health benefits including medical, prescription drug, dental, and vision coverage.
Full Job Description
The BPM RIMedical Evidence Strategy Director role at AstraZeneca is a senior epidemiologist role combining strategy, science, and people management skills. They report to the Head of Medical Evidence Strategy and partner closely with the Head(s) of medical brands.

They drive Integrated Evidence Strategy plan, covering a portfolio from Ph3 projects to post launch marketed products. The scope includes different types of scientific studies, from real-world database observational to pragmatic clinical studies.

They are experts as independent scientific leads for the planning and execution of real-world studies, both primary and secondary, and consult on observational methods. They supervise, develop and coach their direct reports ensuring cohesive efficient ways-of-working within their team and with other key functions. They are responsible for their teams' evidence study delivery from scientific excellence to adherence to timeliness, budget, and compliance with Standard Operating Procedures.

Furthermore, this role is responsible for managing governance activities for medical evidence studies (Global and Local studies) to the highest quality standards. This may include chairing of the protocol Evidence Review Team as well as other activities defined by Standard Operating Procedures.

These responsibilities require an extensive experience within the pharmaceutical industry, with deep knowledge of medical evidence methodologies and significant experience of communicating impactful evidence. To excel in this role, you should bring deep expertise in the design, conduct and analysis of medical research, combined with strategic mindset and people-management skills. Exceptional communication skills when presenting evidence are essential.

TA Evidence Strategy leaders will be expected to have six core capabilities:

- Strategy & Business Acumen

- Evidence Strategy and Research Methodologies

- Decision Making and Matrix management

- Planning and Strategic Sourcing/Partnering

- Effective Communication including Publication

- People management

What You'll Do:
  • Medical Evidence Strategy Leadership:
    • To lead in a partnership with Medical Affairs Leads development of Medical Evidence Strategy, aligned with medical priorities in the TA (Therapeutic Area) and for specific assets.]
    • To identify evidence requirements/gaps and evidence priorities, based on good understanding of clinical practice, disease area and applicable methods.
    • To implement sustainability and health policy objectives
  • Study Delivery and Governance:
    • Responsibility for development and delivery of brand-specific Medical Evidence tactical plans on time&budget with high scientific quality and impact
    • Scientific Lead for evidence studies: Applying appropriate Study Design & Analytical methods to generate robust scientific evidence, based on all applicable research methodologies (ranging from pragmatic interventional studies and implementation science to observational studies based on secondary data and utilization of emerging technology and AI).
    • To lead governance procedures, as applicable, for review and approval of medical studies (defined by SOPs).
  • Impact and Communication:
    • To translate evidence into messaging driving decisions for clinicians, payers, regulators, and internal governance; communicate clearly to senior leadership.
  • Talent and Culture:
    • To lead, coach, and develop a high-performing team; foster a culture of scientific rigor, delivery excellence, and excellence in communicating evidence impact.
  • Cross-Functional Integration:
    • To drive collaboration across Medical, Health Economics/Payer Evidence, Medical/Biostatistics, Market Access, Clinical, and Commercial to deliver cohesive plans and impact.
  • Methodology and Standards:
    • To define and uphold scientific standards, methods, and quality systems for observational research, interventional studies, and evidence synthesis.
  • External Leadership:
    • To represent AZ in scientific forums and partnerships; shape external evidence standards through collaborations and publications.


Minimum Requirements:
  • Doctoral level degree (PhD/PharmD), or MSc/MPH in Epidemiology or Public Health with significant experience (10+ years for both PhD or MSc/MPH) of evidence strategy and generation primarily in pharma business, but also across CRO or academia.
  • Experience with direct people management
  • Proven record of setting strategic and tactical evidence plans
  • Extensive hands-on experience of clinical/observational research, drug development process and relevant guidelines (GCP/ICH)
  • Persuasive communicator in English, with a proven ability to work collaboratively in a multi-cultural environment
  • Ability to drive concise impactful messages from evidence studies
  • Knowledge of drug life cycle management
  • Respiratory* or Immunology* therapeutic and disease area knowledge
  • Broad knowledge of health care systems
  • Integrity and high ethical standards
  • Proven ability to interact widely and effectively across functions, regions and cultures


Desirable Skills:
  • Doctoral level degree in Epidemiology plus MD or PharmD with clinical experience
  • Extensive Pharma industry experience, preferably including experience from local Marketing Company
  • Extensive experience from leading and managing people in a global, matrix environment
  • Experience and proven ability of leading cross-functional teams in evidence generation strategy and delivery to support physician/payer/policy/patient needs
  • Experience with protocol review process and other types of evidence study governance
  • Expertise in Respiratory* or Immunology* disease area


The annual base pay for this position ranges from $ 243,586.40 - 365,379.60 USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered include a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Call to Action:

Step into a role where your leadership turns evidence into access-seize this opportunity to shape the future of payer strategy and patient outcomes today!

Date Posted
14-Jul-2026

Closing Date
27-Jul-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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