AstraZeneca

Scientist

AstraZeneca$90K — $120K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Master's degree with a year of hands-on experience in antibody engineering or protein characterization
  • Bachelor's degree with 4+ years of relevant research experience
  • Expertise in protein purification and analytical methods (SEC, SDS-PAGE, HPLC, ELISA, BLI)
  • Proven experience in antibody expression, purification, and characterization
  • Knowledge of optimizing automation techniques and designing automated workflows

Responsibilities

  • Collaborate with diverse scientists to ensure timely progress on research projects
  • Execute high-throughput cloning, production, and purification of protein therapeutics using automation
  • Work with automation engineers to integrate robotics and analytics into production pipelines
  • Perform biochemical and biophysical profiling of antibodies and fragments
  • Solve process development problems and implement improvements

Benefits

  • Opportunity to work on cutting-edge biologics discovery
  • Collaborative team environment across multiple therapeutic areas
  • Focus on high-throughput techniques and automation
  • Access to advanced technologies and platforms in protein engineering
  • Potential to contribute to groundbreaking research that impacts patient care
Full Job Description
Summary of the Group

Biologics Engineering (BE) is responsible for the discovery and optimization of next generation biologics to create biological drug candidates for all key therapeutic areas such as oncology, respiratory and inflammation, cardiovascular, renal and metabolic diseases. We're constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for the development of in-house biologics discovery platforms and novel drug modalities to address unmet medical needs.

Main Duties & Responsibilities

We are seeking a skilled and highly motivated Scientist to enhance our High Throughput Production & Screening (HTPS) capabilities of biologics. The successful candidate will play a critical role in a dynamic group responsible for high-throughput cloning, expression & purification of antibody therapeutics on a microgram-to-milligram scale and be an advocate for utilizing various automation platforms. The selected individual will be a well-organized and a highly productive scientist that can design and execute experiments efficiently, as well as analyze, interpret and present data to multidisciplinary project teams

  • Collaborate and work with a diverse group of scientists across all therapeutic areas to ensure timely progress in research projects.


  • Execute high-throughput cloning, production and purification of protein therapeutics from mammalian expression systems using process automation and liquid handling robotics.


  • Collaborate with automation engineers to integrate liquid handling robotics and high-throughput analytics into production pipelines.


  • Biochemical, biophysical and functional profiling of antibodies and recombinant antibody fragments.


  • Ability to solve process development problems and implement improved procedures.


Education & Experience Requirements

  • Master's degree with hands-on experience in antibody engineering, cloning and expression, or protein characterization (e.g., UPLC, mass spectrometry) +1 YOE


  • Bachelor's degree with 4+ years of relevant industry or academic research experience


Required Skills

  • Expertise in protein purification techniques and in vitro analytical methods for protein characterization, including SEC, SDS-PAGE, HPLC, ELISA, and BLI.


  • Proven experience in the expression, purification, and comprehensive biochemical/biophysical characterization of various antibody formats (e.g., IgG, Fab, scFv, bispecifics).


  • Knowledge in optimizing and troubleshooting automation techniques, with hands-on experience designing automated workflows.


  • Ability to follow well established SOP's, effectively plan and organize work activities and prioritize task completion to meet project deadlines.


Desired Skills

  • Experience in tissue culture teftherchniques and protein characterization assays.


  • Experience working with multiple antibody formats, troubleshoot common downstream challenges such as low recovery, aggregation and purities.


  • Automation experience with liquid handlers, Green button Go and other platforms a plus.


  • Strong interpersonal and communication skills as well as the ability to work within teams.


  • Good written and verbal communication skills and effective presentation of complex scientific data to cross-functional and senior management.


Date Posted
28-may-2026

Closing Date
02-jun-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

Similar Jobs

More Jobs at AstraZeneca

More Pharmaceuticals & Biotech Jobs

Find similar Scientist jobs: