Duties/Responsibilities:
70% conduct genomic analyses of pediatric cancer etiology and outcome at the direction of faculty members; this includes studies of germline genetic pleiotropy across pediatric cancers; post-GWAS analyses of data from the Admixture and Risk of Acute Leukemia (ADMIRAL) study; analysis of GWAS data for hepatoblastoma and Ewing sarcoma. Responsibilities include:
*Processing raw genomic data, conducting routine QC, report QC results to supervisors
*Independently obtain and match cases with publicly available control data
*Lead logistic regression and other multivariable regression analyses using appropriate statistical genetic software including R, Plink, and SNiPAR.
*Prepare manuscripts in collaboration with Epidemiology & Clinical Research faculty, figures, and written/oral reports for internal and external dissemination, including journal publications and conference presentations.
*Lead bioinformatics efforts on collaborative projects within Pediatric Epidemiology, serving as a liaison across laboratories and providing strategic and technical guidance to enhance the impact of shared research goals. Candidate will be expected to collaborate with other investigators to enhance current projects and develop unique line of inquiry.
*Provide intensive grant application support to faculty including technical sections, power calculations, figures, etc.

20% develop and document genomic analytic pipelines for use by Division students/trainees, including:

*Pipelines for analyzing microsatellite repeats in long-read whole genome sequencing
*Pipeline for integrative studies including expression, protein-level, and metabolome quantitative trait loci
*Pipelines for analysis of family-based genetic data including relatedness-disequilibrium regression and de novo mutation detection

10% obtain and manage external genomic datasets such as from the Database of Genotypes and Phenotypes at the direction of faculty; duties include:

*Maintaining IRB and other administrative approvals
*Tracking data users to ensure compliance
*Ensuring data erasure after study close.

Qualifications

Required Qualifications
Master's Degree in Epidemiology, Statistical Genetics, Population Genetics, Bioinformatics, or closely related field; at least three years of relevant post-bachelor's work and demonstrated skills in programming analyses of genome-scale data. Good interpersonal and communication skills (both oral and written) are also essential, as well as ability for setting priorities, multi-tasking, and working with several faculty researchers to meet numerous deadlines. Ability to provide datasets to collaborators and trainees, and to advise on analysis of these datasets.

Preferred Qualifications
Experience with analysis of human genomic data. Familiarity with cancer epidemiology, sources of cancer data, and especially pediatric cancer data. Ability to obtain and analyze data from disparate sources to conduct integrative analyses. Conversance in non-genomic data and ability to integrate nongenomic data into genomic analyses.

About the Department

Program/Unit Description
The Division of Epidemiology and Clinical Research has nearly a 30 year history of conducting epidemiologic research into the causes of childhood cancer, outcomes during treatment, and late effects among survivors. Currently three faculty work in this area, along with numerous graduate students and postdoctoral fellows. Data to be managed and analyzed include numerous genomewide variant array, whole exome, and whole genome datasets for multiple pediatric cancers. Division research and trainees are supported by multiple NIH and foundation grants, an NIH T32 training grant, and the generous philanthropy of the Children's Cancer Research Fund.

Pay and Benefits

Pay Range: $75,000 - $90,000 ; depending on education/qualifications/experience

Time Appointment: 100% Appointment

Position Type: Faculty and P&A Staff

Please visit the Office of Human Resources website for more information regarding benefit eligibility.

The University offers a comprehensive benefits package that includes:

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program
• Low-cost medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and employer-paid life insurance
• Employee wellbeing program
• Excellent retirement plans with employer contribution
• Public Service Loan Forgiveness (PSLF) opportunity
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost
• Employee Transit Pass with free or reduced rates in the Twin Cities metro area

While our salary ranges provide a framework, it is important to note that most of the
time, the initial pay may not reach the maximum of the range. This approach ensures
that compensation reflects the value and unique contributions of each candidate while
maintaining equity within our organization. As part of our commitment to fair and
equitable compensation, please be aware that the salary offered to incoming candidates
will be based on their individual credentials and experience.

How To Apply

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail [email protected] or call (612) 624-8647.