What Will You Do?The OverviewThe Product Manager will own the clinical endpoints our platform enables for trial sponsors-the full menu of measurements we can collect or deliver in support of proving a cardiovascular drug is safe and effective.
You will decide what we measure and how we prove it holds up: the data we collect from medical devices and wearable sensors, the digital biomarkers we build on top of that data, the lab-based biomarkers, ePRO/eCOA measures, and other assessments that can serve as endpoints in a cardiovascular trial.
The Specifics- Own the full menu of clinical endpoints our platform offers sponsors-digital measures, lab-based biomarkers, ePRO/eCOA, and beyond. Decide what we build, what we buy, and what we partner for, anchored in real sponsor and therapeutic-area need.
- Maintain a clear, prioritized endpoint roadmap, sequencing investments by clinical impact, sponsor demand, and feasibility.
- Track the evolving endpoint landscape-new digital biomarkers, novel sensors, and shifting regulatory expectations-and translate it into where we place our bets.
- Define what data we collect and from which medical devices and wearable sensors, weighing signal fidelity, patient burden, and fitness for the question at hand.
- Evaluate and select sensor and device partners, setting the bar for data quality, interoperability, and regulatory readiness.
- Define the raw data we capture and retain so that today's collection supports tomorrow's biomarkers and endpoints, not just the trial in front of us.
- Partner with Data Science and Clinical to turn raw device and sensor signals into meaningful digital biomarkers, owning the use case, the target population, and the measure's intended claim
- Write clear requirements for new biomarkers and guide them from concept through prototype, pilot, and trial-ready measure.
- Curate the wider endpoint set alongside digital biomarkers-lab-based biomarkers, ePRO/eCOA, and other functional assessments
- Own the fit-for-purpose case for each endpoint, working with Clinical, Data Science, and Regulatory through verification, analytical validation, and clinical validation (e.g., the DiMe V3 framework).
- Stay close to the regulatory bar for endpoints-FDA and EMA expectations, biomarker qualification pathways, and ePRO/eCOA standards-and build the evidence so our endpoints stand up to sponsor and agency scrutiny.
- Translate dense scientific and regulatory requirements into clear, buildable specs for the teams developing and delivering each measure.
- Work with the Chief Medical Officer (CMO) and Clinical to ensure every endpoint reflects clinical reality and answers a real question for cardiovascular trials.
- Partner closely with the Product Manager for AI, Real-World Data & Advanced Analytics so the endpoints you define and the platform they build fit together cleanly-shared data, no duplicated effort, clear ownership.
- Engage directly with trial sponsors to understand their endpoint needs and bring that voice back into the roadmap.
- Collaborate with Quality and Regulatory to ensure data collection and endpoint delivery meet the standards expected in regulated trial environments (e.g., HIPAA, 21 CFR Part 11, GxP).
Who You Are?- 8+ years in product management, clinical science, or endpoint/measurement roles in Digital Health, MedTech, or Life Sciences
- Deep familiarity with clinical trial endpoints across modalities-digital measures, wearable and sensor data, lab-based biomarkers, and ePRO/eCOA
- Hands-on experience taking a measure or biomarker from concept through fit-for-purpose validation
- Working knowledge of the regulatory bar for endpoints (FDA/EMA, biomarker qualification, validation frameworks such as DiMe V3)
- Excellent communication skills, with a knack for turning scientific and regulatory rigor into clear product decisions
Why You'll Love Working Here- Meaningful Compensation: Competitive salary, performance bonus, and equity so you can share in what we build.
- Great Health Coverage: Medical, dental, and vision plans with multiple options and strong company contributions.
- Flexible Spending Perks: HSA, FSA, commuter benefits, and a $1,200 annual Lifestyle Spending Account to support wellness, commuting, family needs, and more.
- Time to Recharge: Generous paid time off, sick leave, and company holidays.
- Family-First Benefits: Paid parental leave, caregiver leave, and support for growing families.
- Security & Peace of Mind: Company-paid life insurance and short- and long-term disability coverage.
- Plan for the Future: 401(k) plan to help you build long-term financial security.
- Care When You Need It: Easy access to telehealth and optional supplemental coverage for life's unexpected moments.
Starting Salary is at $159,000.00 (Exact Compensation may vary based on skills, experience, and location)
