Principal Scientist, Medicinal Chemistry
Bothell, WA 98012 In-Person
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Job Description
Job title: Principal Scientist, Medicinal Chemistry
Company: Immunome, Inc.
Location: Bothell, WA
About Us :
Immunome is a biotechnology company dedicated to developing first-in-class and best-in-class targeted cancer therapies. Our portfolio pursues each target with a modality appropriate to its biology, including immunotherapies, targeted effectors, radioligand therapies and antibody-drug conjugates (ADCs). We believe that pursuing underexplored targets with appropriate drug modalities leads to transformative therapies.
Position summary :
We are seeking a highly motivated and experienced Principal Scientist, Medicinal Chemistry to advance our portfolio of radioligand therapy (RLT) and antibody-drug conjugate (ADC) programs. The successful candidate will be a hands-on leader with expertise in Medicinal Chemistry and proven track record of leading discovery research programs. In this role, the successful candidate will lead efforts for design, synthesis and screening of molecules leading to the identification of novel linker-payloads for ADCs and ligands for targeted radioligand therapy. As a Principal Scientist, you will play a pivotal role in steering our research programs to develop first-in-class and best-in-class targeted cancer therapies.
Key Responsibilities:
Program Leadership: Lead Medicinal Chemistry for a RLT or ADC discovery research program.
Scientific Technical Expertise: Apply deep knowledge of medicinal chemistry principles to design and optimize small molecules for RLT and linker-payloads for ADCs.
Innovation: Drive innovation in the design and synthesis of novel ADC payloads, linker technologies, and ligands for RLT to maximize therapeutic potential.
Collaboration: Collaborate with cross-functional teams, including biology, pharmacology, and ADME/PK, to ensure seamless integration and communication across research and development efforts.
Innovative Research: Drive innovation in the design and synthesis of novel ADC payloads, linker technologies, and ligands for RLT to maximize therapeutic potential.
Intellectual Property: Contribute to the development of intellectual property through patent filings and publications in peer-reviewed journals.
Requirements
Qualifications :
• A Ph.D. in Synthetic Organic or Medicinal Chemistry with a minimum of eight years of experience in the pharmaceutical or biotechnology industry.
• Proven track record in the development of small molecule targeted radioligand therapy and/or linker-payloads for ADC drug candidates.
• Demonstrated ability to lead and inspire a diverse team of scientists.
• Ability to solve complex scientific problems and make data-driven decisions.
• Excellent communication skills and ability to collaborate effectively with cross-functional teams.
• A history of successful publications, patents, and contributions to the field.
• Strong problem-solving skills and a commitment to scientific excellence.
• Flexibility, adaptability, and a passion for innovation and research.
If you are an experienced and innovative medicinal chemist with a passion for leading teams and driving the development of novel therapeutics, we invite you to apply for the position of Principal Scientist, Medicinal Chemistry. Join us in our mission to make a meaningful impact on the lives of patients worldwide.
E/E/O
Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
Salary Description
$144,000 - $177,000
Company: Immunome, Inc.
Location: Bothell, WA
About Us :
Immunome is a biotechnology company dedicated to developing first-in-class and best-in-class targeted cancer therapies. Our portfolio pursues each target with a modality appropriate to its biology, including immunotherapies, targeted effectors, radioligand therapies and antibody-drug conjugates (ADCs). We believe that pursuing underexplored targets with appropriate drug modalities leads to transformative therapies.
Position summary :
We are seeking a highly motivated and experienced Principal Scientist, Medicinal Chemistry to advance our portfolio of radioligand therapy (RLT) and antibody-drug conjugate (ADC) programs. The successful candidate will be a hands-on leader with expertise in Medicinal Chemistry and proven track record of leading discovery research programs. In this role, the successful candidate will lead efforts for design, synthesis and screening of molecules leading to the identification of novel linker-payloads for ADCs and ligands for targeted radioligand therapy. As a Principal Scientist, you will play a pivotal role in steering our research programs to develop first-in-class and best-in-class targeted cancer therapies.
Key Responsibilities:
Program Leadership: Lead Medicinal Chemistry for a RLT or ADC discovery research program.
Scientific Technical Expertise: Apply deep knowledge of medicinal chemistry principles to design and optimize small molecules for RLT and linker-payloads for ADCs.
Innovation: Drive innovation in the design and synthesis of novel ADC payloads, linker technologies, and ligands for RLT to maximize therapeutic potential.
Collaboration: Collaborate with cross-functional teams, including biology, pharmacology, and ADME/PK, to ensure seamless integration and communication across research and development efforts.
Innovative Research: Drive innovation in the design and synthesis of novel ADC payloads, linker technologies, and ligands for RLT to maximize therapeutic potential.
Intellectual Property: Contribute to the development of intellectual property through patent filings and publications in peer-reviewed journals.
Requirements
Qualifications :
• A Ph.D. in Synthetic Organic or Medicinal Chemistry with a minimum of eight years of experience in the pharmaceutical or biotechnology industry.
• Proven track record in the development of small molecule targeted radioligand therapy and/or linker-payloads for ADC drug candidates.
• Demonstrated ability to lead and inspire a diverse team of scientists.
• Ability to solve complex scientific problems and make data-driven decisions.
• Excellent communication skills and ability to collaborate effectively with cross-functional teams.
• A history of successful publications, patents, and contributions to the field.
• Strong problem-solving skills and a commitment to scientific excellence.
• Flexibility, adaptability, and a passion for innovation and research.
If you are an experienced and innovative medicinal chemist with a passion for leading teams and driving the development of novel therapeutics, we invite you to apply for the position of Principal Scientist, Medicinal Chemistry. Join us in our mission to make a meaningful impact on the lives of patients worldwide.
E/E/O
Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
Salary Description
$144,000 - $177,000
About Immunome, Inc.
Learn More About Immunome, Inc.Immunome is a biotechnology company that develops next-generation cancer immunotherapies. The company's proprietary discovery engine identifies novel cancer targets and develops antibody-based therapies to treat cancer. Immunome's lead product candidate, IMM-BCP-01, is a first-in-class cancer immunotherapy that targets a novel cancer antigen. The company is headquartered in Philadelphia, Pennsylvania.
