Merck & Co, Inc

Principal Scientist, Materials Science

Merck & Co, Inc$156K — $247K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's or Master's in relevant field with 12+ years industrial experience, or PhD with 8+ years industrial experience.
  • Expertise in materials science or physical chemistry with characterization techniques.
  • Experience leading cross-functional teams effectively.
  • Demonstrated commitment to mentoring scientists and fostering growth.
  • Strong publication record and verbal/written communication skills.
  • Self-motivated problem solver with a creative mindset.

Responsibilities

  • Conduct physicochemical characterization of pharmaceutical materials.
  • Collaborate on scientific challenges involving crystallization and polymorph selection.
  • Assess drug-excipient compatibility to ensure product effectiveness.
  • Characterize amorphous solid dispersions and evaluate stability.
  • Build and maintain relationships with internal and external scientific communities.
  • Promote a culture of scientific excellence and compliance mindset within teams.

Benefits

  • Comprehensive medical, dental, and vision insurance for employees and their families.
  • Retirement benefits including a 401(k) plan.
  • Paid holidays, vacation, sick, and compassionate leave.
  • Opportunities for annual bonus and long-term incentives.
Full Job Description
Job Description

The Materials & Biophysical Characterization (MBC) group within Analytical Research & Development is seeking a highly motivated and technically focused individual interested in positively impacting our Company's pipeline from discovery through development and commercial launch. This position is for a Pharmaceutical Materials Scientist to be a key member of a team responsible for the physicochemical characterization of pharmaceutical materials including small molecule active pharmaceutical ingredients (API), chemical intermediates, peptides, novel excipients, drug-product intermediates, and drug products.

The candidate will utilize their expertise in physical organic chemistry or materials science as a member of cross-functional teams to tackle scientific challenges related to crystallization, polymorph and salt-selection, drug-excipient compatibility, characterization of amorphous solid dispersions, and physical stability API and drug products. Additional expectations include building a strong network internally and across the external academic and regulatory community. Furthermore, the selected candidate will advance a culture of scientific excellence, a compliance mindset, and collaboration with partners and stakeholders across our company's network such as Discovery Chemistry, Process & Analytical Chemistry, Chemical Engineering and Formulations Sciences.

Education Requirements

Bachelors or Masters degree in Materials Science and Engineering, Chemistry, Chemical Engineering, Pharmaceutical Sciences or related discipline, with a minimum of 12 years relevant industrial experience (non-academic).

OR

PhD in Materials Science and Engineering, Chemistry, Chemical Engineering, Pharmaceutical Sciences or related discipline with a minimum of 8 years relevant industrial experience (non-academic).

Experience and Skills

Required
  • Expertise in materials science or physical chemistry with experience in materials characterization techniques such as X-ray diffraction, thermal analysis, electron microscopy, vibrational spectroscopy, particle size analysis or powder property characterization.
  • Demonstrated experience leading cross-functional teams
  • Commitment to mentoring scientists
  • Strong academic record including publications in peer reviewed journals and presentations at scientific meetings
  • Self-motivated, creative and energetic scientist willing to continually learn and solve complex problems.
  • Strong written and verbal communications


Preferred
  • Expertise with at least one of the following:
  • Active pharmaceutical ingredient (API) polymorph screening and crystallization
  • Chemometric analysis of spectroscopic data
  • Amorphous solid dispersion characterization
  • Modified release dosage form development and characterization.
  • Rheological characterization of complex fluids or suspensions
  • Late-stage product development and regulatory documentation / filing.

#AR&D

Required Skills:
Analytical Chemistry, Analytical Method Development, Assay Development, Bioanalytical Analysis, Chemical Engineering, Chemical Technology, Chromatographic Techniques, Clinical Judgment, Cross-Functional Teamwork, Crystallizations, Dosage Forms, Liquid Chromatography (LC), Materials Science, Mentoring Staff, Method Validation, Thermal Analysis

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

The salary range for this role is
$156,900.00 - $247,000.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:
Regular

Relocation:
Domestic

VISA Sponsorship:
Yes

Travel Requirements:
10%

Flexible Work Arrangements:
Not Applicable

Shift:
Not Indicated

Valid Driving License:
No

Hazardous Material(s):
n/a

Job Posting End Date:
07/25/2026
*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

About Merck & Co, Inc

Schering-Plough Corporation is a major U.S.-based manufacturer of pharmaceuticals. It operates in three segments: Prescription Pharmaceuticals, Animal Health, and Consumer Health Care. Schering-Plough develops products targeting on allergy, cancer, hepatitis, cardiovascular, central nervous system, respiratory system, and more.  It was founded in 1851 by Ernst Christian Friedrich Schering as Schering AG in Germany. Schering-Plough manufactured several pharmaceutical drugs, the most well-known of which were the allergy drugs Claritin and Clarinex, an anti-cholesterol drug Vytorin, and a brain tumor drug Temodar. It also developed drugs targeting on central nervous system and the respiratory system. Schering Plough also owned and operated the major foot care brand name Dr. Scholl's and the skin care line Coppertone. These also became a part of the new company. Schering-Plough was a full member of the European Federation of Pharmaceutical Industries and Associations (EFPIA), a membership which is also maintained by the new Merck.

Merck & Co, Inc Careers

Join the visionary team at Merck & Co, Inc, a global leader in healthcare dedicated to advancing the world of medicine. As part of our professional community, you'll find dynamic job opportunities that foster innovation and leadership across various fields. Merck & Co, Inc is not just a company; it's a place where you can make a difference.

Work You’ll Do

At Merck & Co, Inc, we are committed to improving global health through groundbreaking research and innovative healthcare solutions. Our team is at the forefront of developing new therapies and vaccines that significantly impact public health worldwide. By joining us, you will collaborate with some of the brightest minds in the industry, using your skills to contribute to projects that save and improve lives around the globe.

Explore Career Paths

Whether you're seeking an internship, a graduate opportunity, or a professional position, Merck & Co, Inc offers a range of career paths in environments that promote rapid professional growth and development. Explore job opportunities in research, digital transformation, manufacturing, and more, all while benefiting from a culture that supports diversity and inclusion.

Innovate and Lead

Merck & Co, Inc is an ideal environment for those who lead with curiosity and the drive to innovate. Our leadership is committed to fostering a culture where inventive thinking and collaboration are encouraged, making it a perfect place for professionals who seek to make an impact through their work.

Develop Your Skills

With Merck & Co, Inc, you are not just getting a job; you're gaining access to unparalleled career development opportunities. Enhance your skills through diverse training programs, workshops, and continuous learning courses designed to help you grow at every stage of your career.

Benefits and Culture

We understand that our employees are our greatest asset, which is why we offer competitive benefits designed to support the health and well-being of you and your family. From comprehensive health care coverage and retirement plans to flexible working conditions and wellness programs, our benefits package is designed to meet the diverse needs of our team members.

Join Our Team

Ready to advance your career at Merck & Co, Inc? Search open positions that match your skills and interests. We are continuously hiring and looking for passionate, creative, and solution-driven team players. Prepare your resume, sharpen your interview skills, and become part of a company that's dedicated to making a difference.

Stay Connected

Keep up to date with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Engage with us through our careers blog and by participating in networking events and employment fairs. Subscribe to receive personalized job alerts and the latest news tailored to your preferences. Discover the exciting and rewarding opportunities that await at Merck & Co, Inc. Join us in our mission to improve health and wellness around the world.
Learn more about Merck & Co, Inc
Size
68,000 employees
Market Cap
$282.6 billion
Industry
Net Income
$7 billion
Founded
1668
5 Year Trend
+4.1%
Revenue
$47.9 billion
NASDAQ

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