Eli Lilly

Principal Biologist/Senior Principal Biologist, Immune Aging

Eli Lilly$71K — $187K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Master's degree in Immunology, Cell Biology, Molecular Biology, or related field with 3+ years industry research experience; or Bachelor's with 5+ years industry research experience.
  • Experience with immunoassays like ELISA, MSD, HTRF, and multi-color flow cytometry (FlowJo).
  • Strong foundational knowledge of cell and molecular biology concepts.
  • Hands-on experience isolating and culturing primary human immune cells and working with cell lines.
  • Competent in cellular and biochemical assays in 96- and 384-well formats.

Responsibilities

  • Execute primary human immune cell experiments under project lead's direction.
  • Design and conduct multiparameter flow cytometry and assays for target biology interrogation.
  • Deliver high-quality, decision-grade data while troubleshooting findings independently.
  • Communicate results effectively through written summaries and presentations, while maintaining experimental records.

Benefits

  • Eligible for a company-sponsored 401(k) and pension plan.
  • Includes vacation benefits and eligibility for medical, dental, vision, and prescription drug coverage.
  • Flexible benefit options for healthcare and dependent care spending.
  • Access to life insurance and death benefits, plus various well-being programs.
  • Participation in company bonus program based on performance.
Full Job Description
Lilly is building an exploratory research effort centered on immune aging, with active programs in T cell biology, cellular reprogramming, CAR-T applications, and the immune-stromal interactions that sustain chronic inflammation. We are hiring a Principal Biologist to serve as a hands-on technical driver of this work, executing experiments on programs designed by the project lead, generating decision-grade data, and contributing recognized bench expertise in primary human immune cell biology.

Key Responsibilities
  • Execute primary human immune cell experiments across multiple projects under the direction of the project lead, including isolation, culture, and functional characterization of T cells and other immune populations.
  • Design and run multiparameter flow cytometry and complementary molecular and cellular assays to interrogate target biology, including panel design, FACS sorting, multiplex cytokine quantification, Western blot, qRT-PCR, co-culture systems, and functional readouts of T cell activity and senescence.
  • Deliver decision-grade data through rigorous controls and pre-specified analysis plans; troubleshoot independently using evidence-based reasoning; and surface limitations and unexpected findings proactively.
  • Communicate results clearly through written summaries, presentation-quality figures, and team scientific reviews, while maintaining disciplined experimental records.


Basic Qualifications
  • Master's degree in Immunology, Cell Biology, Molecular Biology, or a closely related discipline, with 3+ years of industry research experience; or a Bachelor's degree with 5+ years of industry research experience.
  • Experience with immunoassays (ELISA, MSD, HTRF), multi-color flow cytometry (staining, acquisition, and analysis in FlowJo), and protein detection methods such as Western blotting.


Preferred Qualifications
  • Working knowledge of cell and molecular biology concepts and a strong grasp of underlying assay principles.
  • Hands-on experience with cell lines, whole blood, and isolation and culture of primary human immune cells.
  • Demonstrated ability to operate and troubleshoot independently, with consistent, reproducible execution and strong technical communication.
  • Experience with cellular and biochemical assays in 96- and 384-well formats.
  • Research experience with small molecules, biologics, and/or genetic medicine modalities.
  • Experience with lentiviral and retroviral systems.
  • Light computational competence for flow data analysis (FlowJo) and basic data wrangling; deep computational expertise is not required.


Additional Information

Current US work authorization is required.

Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$71,250 - $187,000

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly

About Eli Lilly

ICOS Corporation is a biotechnology company that engages in the discovery, development, and commercialization of therapeutic products. It is engaged in the commercialization of treatments for unmet medical conditions, such as benign prostatic hyperplasia, hypertension, pulmonary arterial hypertension, cancer, and inflammatory diseases. It is the developer of a treatment known as Cialis (tadalafil), a product for the treatment of erectile dysfunction through its joint venture with Eli Lilly and Company in North America and Europe. It is also engaged in contract manufacturing services for third parties. It is in a strategic alliance with Solvay Pharmaceuticals, Inc. ICOS Corporation was established in 1989, based in Bothell, Washington. It is currently operated by Eli Lilly and Company.

Eli Lilly Careers

Joining Eli Lilly offers an unparalleled opportunity to become part of a leading global team dedicated to creating a healthier future. As a company revered for its commitment to innovation and leadership in the pharmaceutical industry, Eli Lilly is where your professional journey can flourish. Work You’ll Do At Eli Lilly, we are passionate about transforming patient care and advancing medical innovation. Our team at Eli Lilly is at the forefront of developing groundbreaking solutions in healthcare. By joining us, you will collaborate with some of the brightest minds in the industry, using cutting-edge technology to make real-world impacts. Lead with Innovation and Leadership Eli Lilly stands out in the marketplace by integrating deep industry expertise with robust research and development efforts. We are looking for professionals who are eager to drive change and lead the way in developing therapeutic breakthroughs. Explore Job Opportunities and Growth Eli Lilly offers a variety of career paths, including full-time positions and internships, across multiple functions such as research, marketing, IT, and sales. Whether you are a seasoned professional or a recent graduate, Eli Lilly provides an environment that promotes career growth and learning opportunities. Our commitment to diversity and leadership training ensures that every employee can achieve their potential. Be Part of Our Team Our team at Eli Lilly is committed to excellence and driven by a mission to improve lives. Employees enjoy a supportive culture that values collaboration, creativity, and diversity. We believe that a diverse workforce fosters innovation and helps us better connect with the communities we serve. Benefits and Culture Eli Lilly is dedicated to supporting our employees, offering competitive benefits, wellness programs, and comprehensive health care. Our culture is built on a foundation of respect, integrity, and quality, making Eli Lilly not just a great place to work, but a community to grow with. Networking and Professional Development Eli Lilly encourages continuous professional development and networking. With access to various training programs and mentorship opportunities, employees can enhance their skills and advance their careers. Our leadership is committed to nurturing talent through effective training and development strategies. Join Our Team Discover the exciting job opportunities at Eli Lilly by exploring open positions that match your skills and interests. We are continuously hiring and looking for individuals who are passionate, innovative, and ready to contribute to our mission of making life better for people around the globe. Stay Connected Keep up to date with the latest at Eli Lilly by following our careers blog. Gain insights from industry leaders and get tips on everything from crafting the perfect resume to preparing for your interview. Eli Lilly is not just a company—it's a place where you can make a difference. Explore the positions available and find out how your talents can help change the world. SEARCH ELI LILLY JOBS Stay ahead in your career with Eli Lilly, where innovation, leadership, and a commitment to diversity and growth lead the way to future advancements.
Learn more about Eli Lilly
Size
35,000 employees
Market Cap
$344.2 billion
Industry
Net Income
$6.1 billion
Founded
1876
5 Year Trend
+5.9%
Revenue
$24.5 billion
NASDAQ

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