Member of Technical Staff, Small Molecule DiscoveryThe roleYou will be Latch's authority on small molecule drug discovery and development, from hit to IND. You will own the small molecule benchmarks on our roadmap and decide what correct work looks like across medicinal chemistry, DMPK, safety, and translation.
This is a new function at Latch. You will define what it needs as much as you will execute it.
What you will do- Author and ship the small molecule benchmarks on our roadmap: SmallMolecule-Development-TxBench, SmallMolecule-Translation-TxBench, and the SmallMolecule-TxBench-Long flagship.
- Be the scientific authority at Latch for all things small molecule. Before Latch makes a claim about a small molecule program, you are the final reviewer.
- Potentially collaborate on and run drug programs in the wet lab, guiding discovery and development workflows. We are considering running agent-directed drug programs in a real lab.
- Work with CROs to run experiments and gather data that inform the design of our benchmarks and agents.
- Build a function beyond yourself: advisors, partners, and a hiring plan.
What we look for- You have spent years working hands-on on small molecule programs, in medicinal chemistry, DMPK, or translation, and have carried programs through real decisions.
- You have strong, defensible opinions about what correct work looks like in your field.
- You want to build a function, not fill a seat.
The interviewOne interview will be a detailed discussion of a small molecule program you know well: the chemical series, its liabilities, and how they were solved or why they were not.
LocationThis is a full-time, in-person position at our waterfront office in China Basin, San Francisco. The team works from the office five days a week. The role is not hybrid or remote.
Compensation and benefits- Total compensation ranges from $250,000 to $400,000, depending on experience.
- We believe in long-term incentive plans and provide equity and 401(k) contributions.
- Benefits include a Blue Shield Platinum health plan with 100% of premiums covered, no deductible, and no out-of-pocket costs.
- Daily meals, including lunch and dinner, are provided. Travel and accommodations for scientific conferences and other professional networking trips are included.
