Flagship Pioneering

Machine Learning Research Engineer

Flagship Pioneering$120K — $192K *
Information Technology
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Masters degree or higher preferred in CS, ML, or AI, with flexibility for exceptional candidates
  • Strong foundation in machine learning, deep learning, and natural language processing (NLP)
  • Experience publishing in top ML/NLP conferences (NeurIPS, ICML, ACL, EMNLP) is advantageous
  • Proven track record of deploying LLM applications in production settings
  • Proficiency in Python and ML development tools for large-scale data handling
  • Self-motivated with the ability to thrive in uncertain, dynamic environments
  • Exceptional communication and presentation skills

Responsibilities

  • Design, develop, and deploy ML applications using large language models (LLMs) to solve wellbeing challenges
  • Collaborate with psychological experts to translate insights into computational frameworks
  • Advance techniques in context engineering, agentic AI, and learning from human feedback
  • Build scalable pipelines for data management, labeling, training, and deployment of LLM systems
  • Integrate ML solutions into real-world applications to achieve measurable outcomes
  • Communicate research findings to diverse multidisciplinary audiences

Benefits

  • Healthcare coverage
  • Annual incentive program
  • Retirement benefits
  • Broad range of additional benefits
Full Job Description
The Role

FL105 seeks a talented Machine Learning Research Engineer. The successful candidate will innovate, develop and apply machine learning (ML) methods to create foundational psychological tools. This position is ideal for someone with broad expertise in machine learning, reinforcement learning from human feedback, supervised fine tuning, and computational sciences who is looking to join a very dynamic and innovative environment and pioneer the next frontier of innovation, application, and human-ai interactions enabled by state-of-the-art models. A successful candidate should have a passion for building technologies that enable others to maximize their potential.

Working at FL105, you will have the opportunity to work with world-class scientists, engineers, and researchers who work on cutting-edge ai research and applications.

Key Responsibilities
  • Design, develop, and deploy ML-powered applications that leverage large language models (LLMs) to address complex challenges in wellbeing.
  • Collaborate with psychological experts and translate interdisciplinary insights into computational frameworks.
  • Help advance the state of the art in context engineering, agentic AI and learning from human feedback.
  • Build scalable pipelines for data collection, labeling, training, and deployment of LLM-based systems.
  • Support the integration of ML systems into real-world applications with measurable outcomes.
  • Communicate findings to a multi-disciplinary audience.

Professional Experience & Qualifications
  • Masters level (or above) experience in CS, ML, and AI is preferred, but can be relaxed for exceptional candidates.
  • Strong foundation in machine learning, deep learning, and natural language processing (NLP).
  • Publications at top ML / NLP venues such as NeurIPS, ICML, ACL and EMNLP are a bonus
  • Proven experience deploying LLM-powered applications in production environments, including expertise in frameworks like PyTorch, vLLM, and LangGraph.
  • Proficiency in Python and tools for ML development, large-scale data pipelines and pre-processing, and standard evaluation protocols.
  • Self-motivated and comfortable working in ambiguous, fast-moving environments with evolving goals.
  • Excellent communication and presentation skills.
  • Must be able to think independently and work collaboratively.
  • Experience in a previous startup is a plus.

The salary range for this role is $120,000 - $192,500. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. FL105 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL105's good faith estimate as of the date of publication and may be modified in the future.

About Flagship Pioneering

Flagship Pioneering is a life sciences innovation enterprise that conceives, creates, resources, and develops first-in-category life sciences companies. The firm operates through its Flagship Labs unit, which is a dedicated innovation foundry that invents and launches transformative companies. Flagship Pioneering has created over 100 scientific ventures, resulting in over $34 billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents. The firm's portfolio includes companies in the fields of therapeutics, health technologies, and sustainability. Flagship Pioneering was founded in 2000 and is headquartered in Cambridge, Massachusetts.
Learn more about Flagship Pioneering
Size
500 employees
Industry

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